Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50008349
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50072595((Biphenyl-3-yl-difluoro-methyl)-phosphonium | CHEM...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory activity against PTP1B as a model Protein tyrosine transferase (PTP) using fluorescein diphosphate as substrate at Km concentration (20 uM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50072597((Difluoro-naphthalen-2-yl-methyl)-phosphonium | CH...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibitory activity against PTP1B as a model Protein tyrosine transferase (PTP) using fluorescein diphosphate as substrate at Km concentration (20 uM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50072590(Sodium; biphenyl-3-yl-difluoro-methanesulfonate | ...)
Affinity DataIC50: 1.15E+5nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate as substrate at Km concentration (20 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50072598(CHEMBL109646 | difluoro(naphthalen-2-yl)methanesul...)
Affinity DataIC50: 1.75E+5nMAssay Description:Inhibitory activity against PTP1B as a model Protein tyrosine transferase (PTP) using fluorescein diphosphate as substrate at Km concentration (20 uM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50072593(5-(Biphenyl-3-yl-difluoro-methyl)-1-sodium-1H-tetr...)
Affinity DataIC50: 1.95E+5nMAssay Description:Inhibitory activity against PTP1B as a model Protein tyrosine transferase (PTP) using fluorescein diphosphate as substrate at Km concentration (20 uM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50072592(1-Sodium-5-(difluoro-naphthalen-2-yl-methyl)-1H-te...)
Affinity DataIC50: 2.30E+5nMAssay Description:Inhibitory activity against PTP1B as a model Protein tyrosine transferase (PTP) using fluorescein diphosphate as substrate at Km concentration (20 uM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50072591(2-(Biphenyl-3-yloxy)-2-fluoro-malonic acid | CHEMB...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibitory activity against PTP1B as a model Protein tyrosine transferase (PTP) using fluorescein diphosphate as substrate at Km concentration (20 uM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50072596(2-Fluoro-2-(naphthalen-2-yloxy)-malonic acid | CHE...)
Affinity DataIC50: 3.20E+5nMAssay Description:Inhibitory activity against PTP1B as a model Protein tyrosine transferase (PTP) using fluorescein diphosphate as substrate at Km concentration (20 uM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50072594(Sodium; biphenyl-3-yl-difluoro-acetate | CHEMBL114...)
Affinity DataIC50: 4.35E+5nMAssay Description:Inhibitory activity against PTP1B as a model Protein tyrosine transferase (PTP) using fluorescein diphosphate as substrate at Km concentration (20 uM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50072589(Sodium; difluoro-naphthalen-2-yl-acetate | CHEMBL1...)
Affinity DataIC50: 6.40E+5nMAssay Description:Inhibitory activity against PTP1B as a model Protein tyrosine transferase (PTP) using fluorescein diphosphate as substrate at Km concentration (20 uM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50072590(Sodium; biphenyl-3-yl-difluoro-methanesulfonate | ...)
Affinity DataKi:  4.90E+4nMAssay Description:Binding affinity against Protein tyrosine phosphatase-1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50072593(5-(Biphenyl-3-yl-difluoro-methyl)-1-sodium-1H-tetr...)
Affinity DataKi:  9.80E+4nMAssay Description:Binding affinity against Protein tyrosine phosphatase-1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed