Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50008396
TargetBeta-3 adrenergic receptor(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073045((4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethyl...)
Affinity DataEC50:  60nMAssay Description:Binding affinity towards human Beta-3 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073049(6-(4-{2-[(S)-2-Hydroxy-3-(2-oxo-2,3-dihydro-1H-ben...)
Affinity DataEC50:  30nMAssay Description:Binding affinity towards human Beta-3 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50072375(L-757793 | 4-(3-Hexyl-ureido)-N-{4-[2-((R)-2-hydro...)
Affinity DataEC50:  6.30nMAssay Description:Binding affinity towards human Beta-3 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50070132(N-(4-{2-[(S)-2-Hydroxy-3-(4-hydroxy-phenoxy)-propy...)
Affinity DataEC50:  6.30nMAssay Description:Binding affinity towards human Beta-3 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50070156((S)-4-(3-hexylureido)-N-(4-(2-(1-hydroxy-2-(4-hydr...)
Affinity DataEC50:  0.430nMAssay Description:Binding affinity towards human Beta-3 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073052(5-{2-[(R)-2-(6-Amino-pyridin-3-yl)-2-hydroxy-ethyl...)
Affinity DataEC50:  300nMAssay Description:Binding affinity towards human Beta-3 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073053((2-{2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethylamin...)
Affinity DataEC50:  0.0600nMAssay Description:Binding affinity towards human Beta-3 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073048(2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperi...)
Affinity DataIC50: 0.470nMAssay Description:The compound was tested for the binding affinity against Neuropeptide Y receptor type 5 in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Rat)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50065468(2-(4-Chloro-phenoxymethyl)-4-(3-piperidin-1-yl-pro...)
Affinity DataIC50: 1.70nMAssay Description:The compound was tested for the binding affinity against Neuropeptide Y receptor type 1 in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Rat)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073051(N-[5-(3,4-Dimethoxy-phenyl)-1H-pyrazol-3-yl]-2-(1,...)
Affinity DataIC50: 2.30nMAssay Description:The compound was tested for the binding affinity against Neuropeptide Y receptor type 5 in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Rat)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073055(2-Methyl-4-pyrrolidin-1-yl-6-[(E)-2-(3-trifluorome...)
Affinity DataIC50: 4.10nMAssay Description:The compound was tested for the binding affinity against Neuropeptide Y receptor type 5 in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Rat)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073047(N-[5-(3,4-Dimethoxy-phenyl)-1H-pyrazol-3-yl]-2-nap...)
Affinity DataIC50: 8.30nMAssay Description:The compound was tested for the binding affinity against Neuropeptide Y receptor type 5 in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073054(1-[4-Ethyl-1-(3-methoxymethoxy-phenyl)-cyclohexyl]...)
Affinity DataIC50: 39nMAssay Description:The compound was tested for the binding affinity against Neuropeptide Y receptor type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Rat)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073048(2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperi...)
Affinity DataIC50: 5.00E+3nMAssay Description:The compound was tested for the binding affinity against Neuropeptide Y receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Rat)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073048(2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperi...)
Affinity DataIC50: 5.00E+3nMAssay Description:The compound was tested for the binding affinity against Neuropeptide Y receptor type 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Rat)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073048(2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperi...)
Affinity DataIC50: 5.00E+3nMAssay Description:The compound was tested for the binding affinity against NPY1 (Neuropeptide Y receptor type 1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Mouse)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073050((S)-1-(3-Amino-pentanoyl)-2,3-dihydro-1H-indole-2-...)
Affinity DataKi:  7nMAssay Description:Binding affinity in Cholecystokinin type A receptor binding assay (iv) in miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073046(N-(5-{(R)-2-[(R)-2-(3-Chloro-phenyl)-1-(4-difluoro...)
Affinity DataKi:  9nMAssay Description:Binding affinity towards human Beta-3 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed