Compile Data Set for Download or QSAR
Report error Found 1162 Enz. Inhib. hit(s) with all data for entry = 635
LigandPNGBDBM284360(US10023570, Example 370 | 4-(6-(4-(5-cyclopropyl- ...)
Affinity DataIC50: 2.5nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
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Date in BDB:
1/10/2019
Entry Details
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LigandPNGBDBM284117(US10023570, Example 127 | US10174027, Example 127)
Affinity DataIC50: 2.70nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
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Date in BDB:
1/10/2019
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LigandPNGBDBM284119(US10023570, Example 129 | N-benzyl-4-(5-(3-cyano-6...)
Affinity DataIC50: 2.90nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
Entry Details
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LigandPNGBDBM283931(US10023570, Example 4 | US10174027, Example 4)
Affinity DataIC50: 3.10nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
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Date in BDB:
1/10/2019
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LigandPNGBDBM284552(US10023570, Example 567 | US10174027, Example 567)
Affinity DataIC50: 3.10nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
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Date in BDB:
1/10/2019
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LigandPNGBDBM283981(US10023570, Example 8 | (S)-4-(6-(4-(3- hydroxy-3-...)
Affinity DataIC50: 3.60nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
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Date in BDB:
1/10/2019
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LigandPNGBDBM284088(US10023570, Example 98 | 4-(5-(3-cyano-6-(1-methyl...)
Affinity DataIC50: 3.60nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
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LigandPNGBDBM284013(US10023570, Example 23 | US10174027, Example 23)
Affinity DataIC50: 3.80nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
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LigandPNGBDBM283980(US10023570, Example 7 | (R)-4-(6-(4-(3- hydroxy-3-...)
Affinity DataIC50: 3.90nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
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LigandPNGBDBM284350(US10023570, Example 360 | 4-(6-(4-(2-(5- fluoropyr...)
Affinity DataIC50: 3.90nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
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LigandPNGBDBM284174(US10023570, Example 184 | US10174028, Example 184)
Affinity DataIC50: 4nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
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LigandPNGBDBM284226(US10023570, Example 236 | 1-(5-(3-cyano-6-(1- meth...)
Affinity DataIC50: 4nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
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Date in BDB:
1/10/2019
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LigandPNGBDBM284355(US10023570, Example 365 | 4-(6-(4-(2-(4- cyanophen...)
Affinity DataIC50: 4nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
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LigandPNGBDBM284705(US10023570, Example 740 | US10174027, Example 740)
Affinity DataIC50: 4nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
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LigandPNGBDBM284041(US10023570, Example 51 | 4-(6-(4-(2,6- difluoroben...)
Affinity DataIC50: 4.10nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
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LigandPNGBDBM284555(US10023570, Example 570 | US10174027, Example 570)
Affinity DataIC50: 4.20nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
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LigandPNGBDBM284123(US10023570, Example 133 | 4-(5-(3-cyano-6-(1-methy...)
Affinity DataIC50: 4.30nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
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LigandPNGBDBM283987(US10023570, Example 14 | (R)-6-(1-methyl-1H- pyraz...)
Affinity DataIC50: 4.40nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
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LigandPNGBDBM284043(US10023570, Example 53 | US10174027, Example 53)
Affinity DataIC50: 4.40nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
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LigandPNGBDBM284059(US10023570, Example 69 | 4-(6-(4-benzoylpiperazin-...)
Affinity DataIC50: 4.40nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
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LigandPNGBDBM284068(US10023570, Example 78 | 6-(1-methyl-1H-pyrazol-4-...)
Affinity DataIC50: 4.40nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
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LigandPNGBDBM284472(US10023570, Example 482 | US10174027, Example 482)
Affinity DataIC50: 4.40nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
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LigandPNGBDBM284548(US10023570, Example 563 | US10174027, Example 563)
Affinity DataIC50: 4.40nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
Entry Details
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LigandPNGBDBM283983(US10023570, Example 10 | 4-(6-(4-(2-(2- fluorophen...)
Affinity DataIC50: 4.5nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
Entry Details
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LigandPNGBDBM284129(US10023570, Example 139 | US10174027, Example 139)
Affinity DataIC50: 4.5nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
Entry Details
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LigandPNGBDBM284232(US10023570, Example 242 | US10174027, Example 242)
Affinity DataIC50: 4.5nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
Entry Details
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LigandPNGBDBM284464(US10023570, Example 474 | US10174027, Example 474)
Affinity DataIC50: 4.5nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
Entry Details
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LigandPNGBDBM284476(US10023570, Example 489 | US10174027, Example 489)
Affinity DataIC50: 4.5nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
Entry Details
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LigandPNGBDBM283978(US10023570, Example 5 | 6-(1-methyl-1H- pyrazol-4-...)
Affinity DataIC50: 4.60nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
Entry Details
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LigandPNGBDBM284431(US10023570, Example 441 | 4-(6-(4-(2,6- difluorobe...)
Affinity DataIC50: 4.70nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
Entry Details
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LigandPNGBDBM284072(US10023570, Example 82 | US10174027, Example 82)
Affinity DataIC50: 4.80nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
Entry Details
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LigandPNGBDBM283979(US10023570, Example 6 | (S)-4-(6-(4-(2- hydroxy-2-...)
Affinity DataIC50: 4.90nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
Entry Details
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LigandPNGBDBM284441(US10023570, Example 451 | 4-(6-(4-(2- methoxybenzy...)
Affinity DataIC50: 4.90nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
Entry Details
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LigandPNGBDBM284629(US10023570, Example 664 | US10174027, Example 664)
Affinity DataIC50: 4.90nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
Entry Details
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LigandPNGBDBM284015(US10023570, Example 25 | 6-(1-methyl-1H-pyrazol-4-...)
Affinity DataIC50: 5nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
Entry Details
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LigandPNGBDBM284189(US10023570, Example 199 | US10174028, Example 199)
Affinity DataIC50: 5.10nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
Entry Details
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LigandPNGBDBM284348(US10023570, Example 358 | 6-(1-methyl-1H-pyrazol- ...)
Affinity DataIC50: 5.10nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
Entry Details
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LigandPNGBDBM284526(US10023570, Example 540 | 4-(6-(2,9- diazaspiro[5....)
Affinity DataIC50: 5.10nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
Entry Details
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LigandPNGBDBM284080(US10023570, Example 90 | 4-(6-(4- (isobutylsulfony...)
Affinity DataIC50: 5.20nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
Entry Details
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LigandPNGBDBM284527(US10023570, Example 541 | 4-(6-(1,8- diazaspiro[4....)
Affinity DataIC50: 5.20nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
Entry Details
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LigandPNGBDBM284567(US10023570, Example 586 | US10174027, Example 586)
Affinity DataIC50: 5.20nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
Entry Details
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LigandPNGBDBM283982(US10023570, Example 9 | (R)-4-(6-(4-(2- hydroxy-3-...)
Affinity DataIC50: 5.30nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
Entry Details
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LigandPNGBDBM284077(BDBM320540 | US10023570, Example 87)
Affinity DataIC50: 5.30nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
Entry Details
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LigandPNGBDBM284128(US10023570, Example 138 | US10174027, Example 138)
Affinity DataIC50: 5.40nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
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LigandPNGBDBM284379(US10023570, Example 389 | 4-(6-(4-(3- ethylpyrroli...)
Affinity DataIC50: 5.40nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
Entry Details
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LigandPNGBDBM284051(US10023570, Example 61 | (S)-6-(1-methyl-1H-pyrazo...)
Affinity DataIC50: 5.5nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
Entry Details
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LigandPNGBDBM284124(US10023570, Example 134 | 4-(5-(3-cyano-6-(1-methy...)
Affinity DataIC50: 5.5nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
Entry Details
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LigandPNGBDBM284374(US10023570, Example 384 | 4-(6-(4-(6,6-dimethyl- 3...)
Affinity DataIC50: 5.5nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
Entry Details
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LigandPNGBDBM284440(US10023570, Example 450 | 4-(6-(4-(3- methoxybenzy...)
Affinity DataIC50: 5.5nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
Entry Details
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LigandPNGBDBM284081(US10023570, Example 91 | 6-(1-methyl-1H-pyrazol-4-...)
Affinity DataIC50: 5.60nMpH: 7.4Assay Description:Compounds of General Formula I were screened for their ability to inhibit wild type and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2019
Entry Details
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