Compile Data Set for Download or QSAR
Report error Found 53 Enz. Inhib. hit(s) with all data for entry = 785
TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290450(2{[4-(4-Cyanonaphthalen)isoquinolin-6-yl]thio}-2-m...)
Affinity DataIC50: 8nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290480(US10100016, Compound 45B)
Affinity DataIC50: 10nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290470(US10100016, Compound 43A)
Affinity DataIC50: 11nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290481(3-[4-(4-Cyanonaphthalen-1-yl)isoquinolin-6-yl]-2,2...)
Affinity DataIC50: 12nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290489(3-[4-(4-Cyanophenyl)thieno[2,3-c]pyridin-2-yl]-2,2...)
Affinity DataIC50: 12nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290479(3-[4-(4-Cyanonaphthalen-1-yl)isoquinolin-6-yl]-2-m...)
Affinity DataIC50: 15nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290448(2{[4-(4-Cyanophenyl)isoquinolin-6-yl]thio-2-methyl...)
Affinity DataIC50: 15nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290490(1-{[4-(4-cyanonaphthalen-1-yl)isoquinolin-6-yl]thi...)
Affinity DataIC50: 18nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290487(3-[4-(4-Cyanonaphthalen-1-yl)thieno[2,3-c]pyridin-...)
Affinity DataIC50: 18nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290488(2-{[4-(2-Chloro-4-cyanophenyl)isoquinolin-6-yl]thi...)
Affinity DataIC50: 18nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290515(3-[4-(4-Cyanophenyl)isoquinolin-6-yl]-2,2-dimethyl...)
Affinity DataIC50: 19nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290467(2{[4-(5-Cyanonaphthalen-1-yl)isoquinolin-6-yl]thio...)
Affinity DataIC50: 19nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290477(3-[4-(4-Cyanonaphthalen-1-yl)isoquinolin-6-yl]buty...)
Affinity DataIC50: 24nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290468(3-[4-(4-Cyanonaphthalen-1-yl)thieno[2,3-c]pyridin-...)
Affinity DataIC50: 24nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290457(3-[4-[(4-Cyanonaphthalen-1-yl)thieno[2,3-c]pyridin...)
Affinity DataIC50: 35nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290599(3-[7-(4-Cyanonaphthalen-1-yl)thieno[3,2-c]pyridine...)
Affinity DataIC50: 37nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290472(US10100016, Compound 43B)
Affinity DataIC50: 37nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290474(US10100016, Compound 44A)
Affinity DataIC50: 38nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290447(3-[7-(4-Cyanophenyl)thieno[3,2-c]pyridin-2-yl]-2,2...)
Affinity DataIC50: 42nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290484(US10100016, Compound 46B)
Affinity DataIC50: 51nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290485(2-{[4-(3-Chloro-4-cyanophenyl)isoquinolin-6-yl]thi...)
Affinity DataIC50: 55nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290462(2{[4-(4-Cyano-2-fluorophenyl)isoquinolin-6-yl]thio...)
Affinity DataIC50: 57nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290469(2-{[4-(8-Cyano-2,3-dihydro-1,4-benzodioxan-5-yl)is...)
Affinity DataIC50: 62nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290471(2-{[4-(4-Cyano-7-fluoronaphthalen-1-yl)isoquinolin...)
Affinity DataIC50: 71nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290439(3-[7-(4-Cyanonaphthalen-1-yl)thieno[3,2-c]pyridin-...)
Affinity DataIC50: 87nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290483(2-{[4-(4-Cyanonaphthalen-1-yl)isoquinolin-6-yl]thi...)
Affinity DataIC50: 100nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290431(RDEA3170 | US10100016, Verinurad (RDEA3170) | CAS ...)
Affinity DataIC50: 113nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290491(2-[4-(4-Cyanonaphthalen-1-yl)isoquinolin-6-yl]-2-m...)
Affinity DataIC50: 116nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290494(2-({1-[(2,6-dichlorophenyl)methyl]-3-methyl-1H-ind...)
Affinity DataIC50: 119nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290465(2{[4-(4-Cyanonaphthalen-1-yl)-8-fluoroisoquinolin-...)
Affinity DataIC50: 127nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290449(3-[7-(4-Cyanonaphthalen-1-yl)thieno[3,2-c]pyridin-...)
Affinity DataIC50: 139nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290482(US10100016, Compound 46A)
Affinity DataIC50: 148nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290444(3-[4-(4-Cyanophenyl)isoquinolin-6-yl]propionic Aci...)
Affinity DataIC50: 161nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290473(3-[4-(4-Cyanophenyl)isoquinolin-6-yl]butyric Acid ...)
Affinity DataIC50: 189nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290461(3-[4-(4-Cyanonaphthalen-1-yl)-1-benzothiophen-2-yl...)
Affinity DataIC50: 209nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290452(2{[4-(4-Cyanophenyl)isoquinolin-6-yl]oxy}-2-methyl...)
Affinity DataIC50: 214nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290492(3-{3-[(2, 6-dichlorophenyl)methyl]-1-methylimidazo...)
Affinity DataIC50: 289nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290446(2-[4-(4-Cyanonaphthalen-1-yl)isoquinolin-6-yl]acet...)
Affinity DataIC50: 327nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290475((2E)-3-[4-(4-Cyanonaphthalen-1-yl)isoquinolin-6-yl...)
Affinity DataIC50: 385nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290455(3-{4-[(2,6-Dichlorophenyl)methyl]-1-benzothiophene...)
Affinity DataIC50: 542nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290478(US10100016, Compound 45A)
Affinity DataIC50: 580nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290466(3-[4-(4-Cyanonaphthalen-1-yl)thieno[2,3-c]pyridin-...)
Affinity DataIC50: 934nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290493(2-{[4-(4-Cyanonaphthalen-1-yl)phthalazin-6-yl]thio...)
Affinity DataIC50: 971nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290597(2-{[5-(4-Cyanophenyl)imidazo[1,2-a]pyridin-6-yl]th...)
Affinity DataIC50: 1.73E+3nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290476(US10100016, Compound 44B)
Affinity DataIC50: 1.86E+3nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290451(3-{7-[(2,6-Dichlorophenyl)methyl]-1-benzothiophene...)
Affinity DataIC50: 2.41E+3nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290440(4-(4-cyanophenyl)isoquinoline-6-carboxylic Acid |...)
Affinity DataIC50: 2.53E+3nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290458(US10100016, Compound 7B)
Affinity DataIC50: 2.69E+3nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290600(7-(4-Cyanonaphthalen-1-yl)thieno[3,2-c]pyridin-2-f...)
Affinity DataIC50: 2.86E+3nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetSolute carrier family 22 member 12(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM290443(2-[7-(4-Cyanonaphthalen-1-yl)thieno[3,2-c]pyridin-...)
Affinity DataIC50: 3.42E+3nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

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