Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 1027
TargetBile acid receptor(Human)
Enanta Pharmaceuticals

US Patent
LigandPNGBDBM21674(Chenodeoxycholic Acid | CDCA | (4R)-4-[(1S,2S,5R,7...)
Affinity DataEC50: >1.00E+3nMAssay Description:Determination of a ligand mediated Gal4 promoter driven transactivation to quantify ligand binding mediated activation of FXR. FXR Reporter Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
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PDB3D3D Structure (crystal)
TargetBile acid receptor(Human)
Enanta Pharmaceuticals

US Patent
LigandPNGBDBM303496(US10138228, Example 1)
Affinity DataEC50:  550nMAssay Description:Determination of a ligand mediated Gal4 promoter driven transactivation to quantify ligand binding mediated activation of FXR. FXR Reporter Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
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TargetBile acid receptor(Human)
Enanta Pharmaceuticals

US Patent
LigandPNGBDBM303497(US10138228, Example 2)
Affinity DataEC50:  5.50E+3nMAssay Description:Determination of a ligand mediated Gal4 promoter driven transactivation to quantify ligand binding mediated activation of FXR. FXR Reporter Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent

TargetBile acid receptor(Human)
Enanta Pharmaceuticals

US Patent
LigandPNGBDBM303498(US10138228, Example 3)
Affinity DataEC50: <100nMAssay Description:Determination of a ligand mediated Gal4 promoter driven transactivation to quantify ligand binding mediated activation of FXR. FXR Reporter Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent