Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 1172
TargetCalcitonin gene-related peptide 1(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM311886(US10166226, Example 1 | N-[(2R)-1-[4-(1H-imidazol-...)
Affinity DataKi:  0.0500nMAssay Description:Human CGRP receptors (consisting of CRLR and RAMP1) expressed in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2019
Entry Details
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TargetCalcitonin gene-related peptide 1(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM312053(US10166226, Example 9 | 5-{1'-[(2R)-3-(7-methyl-1H...)
Affinity DataKi:  0.0500nMAssay Description:Human CGRP receptors (consisting of CRLR and RAMP1) expressed in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2019
Entry Details
Go to US Patent

TargetCalcitonin gene-related peptide 1(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM312050(US10166226, Example 6 | ethyl 5-{1'-[(2R)-3-(7-met...)
Affinity DataKi:  0.0630nMAssay Description:Human CGRP receptors (consisting of CRLR and RAMP1) expressed in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2019
Entry Details
Go to US Patent

TargetCalcitonin gene-related peptide 1(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM311913(US10166226, Example 2 | N-[(2R)-1-[4-(4-methyl-1H-...)
Affinity DataKi:  0.0790nMAssay Description:Human CGRP receptors (consisting of CRLR and RAMP1) expressed in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2019
Entry Details
Go to US Patent

TargetCalcitonin gene-related peptide 1(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM312002(US10166226, Example 4 | N-{(2R)-3-(7-methyl-1H-ind...)
Affinity DataKi:  0.100nMAssay Description:Human CGRP receptors (consisting of CRLR and RAMP1) expressed in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2019
Entry Details
Go to US Patent

TargetCalcitonin gene-related peptide 1(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM312052(US10166226, Example 8 | N-{(2R)-3-(7-methyl-1H-ind...)
Affinity DataKi:  0.100nMAssay Description:Human CGRP receptors (consisting of CRLR and RAMP1) expressed in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2019
Entry Details
Go to US Patent

TargetCalcitonin gene-related peptide 1(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM312049(US10166226, Example 5 | 4-(7-fluoro-2-oxo-1,2-dihy...)
Affinity DataKi:  0.126nMAssay Description:Human CGRP receptors (consisting of CRLR and RAMP1) expressed in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2019
Entry Details
Go to US Patent

TargetCalcitonin gene-related peptide 1(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM311965(US10166226, Example 3 | N-{(2R)-3-(7-methyl-1H-ind...)
Affinity DataKi:  0.158nMAssay Description:Human CGRP receptors (consisting of CRLR and RAMP1) expressed in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2019
Entry Details
Go to US Patent

TargetCalcitonin gene-related peptide 1(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM312051(US10166226, Example 7 | N-{(2R)-3-(7-methyl-1H-ind...)
Affinity DataKi:  0.158nMAssay Description:Human CGRP receptors (consisting of CRLR and RAMP1) expressed in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2019
Entry Details
Go to US Patent