Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 1236
TargetEpidermal growth factor receptor [T790M,L858R](Human)
Jiangsu Medolution

US Patent
LigandPNGBDBM149404(US8975249, I-4 | CO-1686 | Rociletinib | AVL-301 |...)
Affinity DataKd:  1.40nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor [T790M,L858R](Human)
Jiangsu Medolution

US Patent
LigandPNGBDBM313221(N-[3-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-(tr...)
Affinity DataKd:  0.540nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Jiangsu Medolution

US Patent
LigandPNGBDBM313222(N-[3-[[2-[4-(4-ethylpiperazin-1-yl)anilino]-5-(tri...)
Affinity DataKd:  0.0370nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Jiangsu Medolution

US Patent
LigandPNGBDBM313223(N-[3-[[2-[4-(4-ethylpiperazin-1-yl)-2-methoxy-anil...)
Affinity DataKd:  0.280nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor(Human)
Jiangsu Medolution

US Patent
LigandPNGBDBM50383274(CHEMBL1229592 | US9670213, WZ4002 | US10167264, WZ...)
Affinity DataKd:  46nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Jiangsu Medolution

US Patent
LigandPNGBDBM50383274(CHEMBL1229592 | US9670213, WZ4002 | US10167264, WZ...)
Affinity DataKd:  12nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Jiangsu Medolution

US Patent
LigandPNGBDBM313221(N-[3-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-(tr...)
Affinity DataKd:  84nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Jiangsu Medolution

US Patent
LigandPNGBDBM313221(N-[3-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-(tr...)
Affinity DataKd:  26nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor(Human)
Jiangsu Medolution

US Patent
LigandPNGBDBM313222(N-[3-[[2-[4-(4-ethylpiperazin-1-yl)anilino]-5-(tri...)
Affinity DataKd:  15nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Jiangsu Medolution

US Patent
LigandPNGBDBM313222(N-[3-[[2-[4-(4-ethylpiperazin-1-yl)anilino]-5-(tri...)
Affinity DataKd:  4nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
Go to US Patent