Compile Data Set for Download or QSAR
Report error Found 2116 Enz. Inhib. hit(s) with all data for entry = 1300
LigandPNGBDBM305704(US10144734, Example 722 | 2-chloro-N-((3S,4S)-1-(5...)
Affinity DataIC50: 2nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305705(US10144734, Example 723 | 2-chloro-N-((3S,4S)-1-(5...)
Affinity DataIC50: 3nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305757(US10144734, Example 775 | 3-chloro-N-(1-(5-(3- cya...)
Affinity DataIC50: 3nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305759(US10144734, Example 777 | 3-chloro-N-(1-(5-(3- cya...)
Affinity DataIC50: 3nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305765(US10144734, Example 783 | 2-chloro-N-(1-(5-(3- cya...)
Affinity DataIC50: 3nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305468(US10144734, Example 485 | US10172845, Example 485 ...)
Affinity DataIC50: 3.70nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305672(US10144734, Example 690 | US10172845, Example 690 ...)
Affinity DataIC50: 3.70nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305707(US10144734, Example 725 | N-((3S,4S)-1-(5-(3-cyano...)
Affinity DataIC50: 4nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305724(US10144734, Example 742 | 4-(6-(4-(3-fluorobenzyl)...)
Affinity DataIC50: 4nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305752(US10144734, Example 770 | US10172845, Example 770 ...)
Affinity DataIC50: 4nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305355(US10144734, Example 371 | US10172845, Example 371 ...)
Affinity DataIC50: 4.20nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305346(US11648243, Example 362 | US10144734, Example 362 ...)
Affinity DataIC50: 4.40nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305687(US10144734, Example 705 | US10172845, Example 705 ...)
Affinity DataIC50: 4.60nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305171(4-(6-(3-(3,5- difluorophenoxy)azetidin- 1-yl)pyrid...)
Affinity DataIC50: 5nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305670(US10144734, Example 688 | US10172845, Example 688 ...)
Affinity DataIC50: 5nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305712(US10144734, Example 730 | N-((3S,4S)-3-amino-1-(5-...)
Affinity DataIC50: 5nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305713(US10144734, Example 731 | N-((3S,4S)-3-amino-1-(5-...)
Affinity DataIC50: 5nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305776(US10144734, Example 794 | 2-chloro-N-(1-(5-(3- cya...)
Affinity DataIC50: 5nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305778(US10144734, Example 796 | 3-chloro-N-(1-(5-(3- cya...)
Affinity DataIC50: 5nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305789(US10144734, Example 807 | US10172845, Example 807 ...)
Affinity DataIC50: 5nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305662(US10144734, Example 680 | US10172845, Example 680 ...)
Affinity DataIC50: 5.20nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305071(US10144734, Example 87 | US10172845, Example 87 | ...)
Affinity DataIC50: 5.30nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM315710(US10172845, Example 363 | US10441581, Example 363 ...)
Affinity DataIC50: 5.5nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305470(US10144734, Example 487 | US10172845, Example 487 ...)
Affinity DataIC50: 5.5nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305367(US10144734, Example 384 | US10172845, Example 384 ...)
Affinity DataIC50: 5.70nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305152(4-(6-(3-(3- fluorophenoxy)azetidin- 1-yl)pyridin-3...)
Affinity DataIC50: 5.80nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305368(US10144734, Example 385 | US10172845, Example 385 ...)
Affinity DataIC50: 5.80nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305579(US10144734, Example 597 | US10172845, Example 597 ...)
Affinity DataIC50: 6nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305675(US10144734, Example 693 | US10172845, Example 693 ...)
Affinity DataIC50: 6nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305693(US10144734, Example 711 | 2-chloro-N-((3S,4S)-1-(5...)
Affinity DataIC50: 6nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305738(US10144734, Example 756 | 6-ethoxy-4-(6-(4-(3- flu...)
Affinity DataIC50: 6nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305790(US10144734, Example 808 | (S)-N-(4-benzyl-1-(5-(3-...)
Affinity DataIC50: 6nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305795(US10144734, Example 813 | (R)-N-(4-benzyl-1-(5-(3-...)
Affinity DataIC50: 6nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305285(US11648243, Example 301 | US10144734, Example 301 ...)
Affinity DataIC50: 6.10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305680(US10144734, Example 698 | US10172845, Example 698 ...)
Affinity DataIC50: 6.10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305683(US10144734, Example 701 | US10172845, Example 701 ...)
Affinity DataIC50: 6.10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305417(3-chloro-N-(1-(5-(3- cyano-6- methoxypyrazolo[1,5-...)
Affinity DataIC50: 6.20nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305029(US10144734, Example 45 | US10172845, Example 45 | ...)
Affinity DataIC50: 6.30nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM305638(US10144734, Example 656 | US10172845, Example 656 ...)
Affinity DataIC50: 6.30nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305376(US10144734, Example 393 | US10172845, Example 393 ...)
Affinity DataIC50: 6.40nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305511(US10144734, Example 528 | US10172845, Example 528 ...)
Affinity DataIC50: 6.40nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305633(US10144734, Example 651 | US10172845, Example 651 ...)
Affinity DataIC50: 6.5nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM305302(US11648243, Example 318 | US10144734, Example 318 ...)
Affinity DataIC50: 6.60nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM305318(US11648243, Example 334 | US10144734, Example 334 ...)
Affinity DataIC50: 6.60nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM305026(US10144734, Example 42 | US10172845, Example 42 | ...)
Affinity DataIC50: 6.70nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305374(US10144734, Example 391 | US10172845, Example 391 ...)
Affinity DataIC50: 6.70nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
Entry Details
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LigandPNGBDBM305283(US11648243, Example 299 | US10144734, Example 299 ...)
Affinity DataIC50: 6.80nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305398(US10144734, Example 415 | US10172845, Example 415 ...)
Affinity DataIC50: 6.90nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305711(US10144734, Example 729 | US10172845, Example 729 ...)
Affinity DataIC50: 7nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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LigandPNGBDBM305736(US10144734, Example 754 | 4-(6-(4-((5-fluoropyridi...)
Affinity DataIC50: 7nMAssay Description:Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2019
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