Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 2220
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165927(US9067931, 75 | US10214524, Example 75)
Affinity DataKi: <0.100nMAssay Description:Rat brain tissue (hippocampus or whole brain) is homogenized in homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethylsulphon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165926(US9067931, 73 | US10214524, Example 73)
Affinity DataKi: <1nMAssay Description:Rat brain tissue (hippocampus or whole brain) is homogenized in homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethylsulphon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165925(US9067931, 20 | US10214524, Example 20)
Affinity DataKi:  1.60nMAssay Description:Rat brain tissue (hippocampus or whole brain) is homogenized in homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethylsulphon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165935(US9067931, 154 | US10214524, Example 154)
Affinity DataKi:  3nMAssay Description:Rat brain tissue (hippocampus or whole brain) is homogenized in homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethylsulphon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165928(US9067931, 76 | US10214524, Example 76)
Affinity DataKi:  3.30nMAssay Description:Rat brain tissue (hippocampus or whole brain) is homogenized in homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethylsulphon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165937(US9067931, 175 | US10214524, Example 175)
Affinity DataKi:  8.30nMAssay Description:Rat brain tissue (hippocampus or whole brain) is homogenized in homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethylsulphon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165929(US9067931, 90 | US10214524, Example 90)
Affinity DataKi:  14nMAssay Description:Rat brain tissue (hippocampus or whole brain) is homogenized in homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethylsulphon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165936(US9067931, 163 | US10214524, Example 163)
Affinity DataKi:  14nMAssay Description:Rat brain tissue (hippocampus or whole brain) is homogenized in homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethylsulphon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165930(US9067931, 108 | US10214524, Example 108)
Affinity DataKi:  17nMAssay Description:Rat brain tissue (hippocampus or whole brain) is homogenized in homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethylsulphon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165931(US9067931, 116 | US10214524, Example 116)
Affinity DataKi:  17nMAssay Description:Rat brain tissue (hippocampus or whole brain) is homogenized in homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethylsulphon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165923(US9067931, 17 | US10214524, Example 17)
Affinity DataKi:  17nMAssay Description:Rat brain tissue (hippocampus or whole brain) is homogenized in homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethylsulphon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165924(US9067931, 19 | US10214524, Example 19)
Affinity DataKi:  20nMAssay Description:Rat brain tissue (hippocampus or whole brain) is homogenized in homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethylsulphon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165922(US9067931, 4 | US10214524, Example 4)
Affinity DataKi:  24nMAssay Description:Rat brain tissue (hippocampus or whole brain) is homogenized in homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethylsulphon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM50393246(CHEMBL2151440 | US9067931, 130 | US10214524, Examp...)
Affinity DataKi:  26nMAssay Description:Rat brain tissue (hippocampus or whole brain) is homogenized in homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethylsulphon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165933(US9067931, 150 | US10214524, Example 150)
Affinity DataKi:  35nMAssay Description:Rat brain tissue (hippocampus or whole brain) is homogenized in homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethylsulphon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165921(US9067931, 3 | US10214524, Example 3)
Affinity DataKi:  60nMAssay Description:Rat brain tissue (hippocampus or whole brain) is homogenized in homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethylsulphon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM50393246(CHEMBL2151440 | US9067931, 130 | US10214524, Examp...)
Affinity DataKi:  62nMAssay Description:Rat brain tissue (hippocampus or whole brain) is homogenized in homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethylsulphon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165934(US9067931, 151 | US10214524, Example 151)
Affinity DataKi:  88nMAssay Description:Rat brain tissue (hippocampus or whole brain) is homogenized in homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethylsulphon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165932(US9067931, 149 | US10214524, Example 149)
Affinity DataKi:  97nMAssay Description:Rat brain tissue (hippocampus or whole brain) is homogenized in homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethylsulphon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bayer Intellectual Property

US Patent
LigandPNGBDBM165938(US9067931, 186 | US10214524, Example 186)
Affinity DataKi:  120nMAssay Description:Rat brain tissue (hippocampus or whole brain) is homogenized in homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethylsulphon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent