Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 2476
TargetCystathionine gamma-lyase(Human)
Sova Pharmaceuticals

US Patent
LigandPNGBDBM367665(US10227314, Example 4 | (S)-1-(1H-1,2,4-triazol-5-...)
Affinity DataIC50: 2.50E+4nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetCystathionine gamma-lyase(Human)
Sova Pharmaceuticals

US Patent
LigandPNGBDBM367664(US10227314, Example 3 | (S)-3-(1-aminobut-3-ynyl)-...)
Affinity DataIC50: 2.50E+4nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetCystathionine gamma-lyase(Human)
Sova Pharmaceuticals

US Patent
LigandPNGBDBM367663(US10227314, Example 2 | (S)-1-(1H-tetrazol-5-yl-bu...)
Affinity DataIC50: 2.50E+4nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetCystathionine gamma-lyase(Human)
Sova Pharmaceuticals

US Patent
LigandPNGBDBM367672(US10227314, Compound (S)-2-aminopent-4-ynoic acid)
Affinity DataIC50: 2.50E+4nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetCystathionine gamma-lyase(Human)
Sova Pharmaceuticals

US Patent
LigandPNGBDBM367671(US10227314, Compound 2-aminopent-4-ynoic acid)
Affinity DataIC50: 2.50E+4nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetCystathionine gamma-lyase(Human)
Sova Pharmaceuticals

US Patent
LigandPNGBDBM367674(US10227314, Compound 2-amino-3-cyanopropanoic acid)
Affinity DataIC50: 2.50E+4nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetCystathionine gamma-lyase(Human)
Sova Pharmaceuticals

US Patent
LigandPNGBDBM367662(US10227314, Example 1 | 3-amino-3-(1H-tetrazol-5-y...)
Affinity DataIC50: 1.00E+5nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetCystathionine gamma-lyase(Human)
Sova Pharmaceuticals

US Patent
LigandPNGBDBM367667(US10227314, Example 6 | (S)-5-(1-aminobut-3-ynyl)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetCystathionine gamma-lyase(Human)
Sova Pharmaceuticals

US Patent
LigandPNGBDBM367666(US10227314, Example 5 | (S)-1-(3-(trifluoromethyl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetCystathionine gamma-lyase(Human)
Sova Pharmaceuticals

US Patent
LigandPNGBDBM367673(US10227314, Compound (R)-2-aminopent-4-ynoic acid)
Affinity DataIC50: 1.00E+5nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetCystathionine gamma-lyase(Human)
Sova Pharmaceuticals

US Patent
LigandPNGBDBM367669(US10227314, Example 8 | (S)-2-amino-N-(phenylsulfo...)
Affinity DataIC50: 1.25E+5nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetCystathionine gamma-lyase(Human)
Sova Pharmaceuticals

US Patent
LigandPNGBDBM367668(US10227314, Example 7 | (S)-2-amino-N-(2H-tetrazol...)
Affinity DataIC50: 1.25E+5nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetCystathionine gamma-lyase(Human)
Sova Pharmaceuticals

US Patent
LigandPNGBDBM367670(US10227314, Example 9 | (S)-2-amino-N-(methylsulfo...)
Affinity DataIC50: 1.25E+5nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent