Compile Data Set for Download or QSAR
Report error Found 245 Enz. Inhib. hit(s) with all data for entry = 2524
TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370039(4-((R)-8-((R)-2-(5-Ethyl-2-fluorobenzamido)-3-meth...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370038(2-Fluoro-N-((2R)-1-(1-(4-methoxyphenyl)-2,3-dimeth...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370037((R)—N-(1-Cyclopentyl-2-(3-methyl-1-(1-methyl-...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370036((R)-3-Chloro-N-(3-methyl-1-(3-methyl-1-(1-methyl-6...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370043((R)—N-(1-(1-(1H-Indazol-5-yl)-3-methyl-4-oxo-...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370042(4-((S)-8-((R)-2-(2-Fluoro-5-(trifluoromethyl)benza...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370041(4-((R)-8-((R)-2-(2-Fluoro-5-(trifluoromethyl)benza...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370040(4-((S)-8-((R)-2-(5-Ethyl-2-fluorobenzamido)-3-meth...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370031((R)-5-Ethyl-2-fluoro-N-(1-(1-(4-methoxyphenyl)-3-m...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370030((R)-5-Ethyl-2-fluoro-N-(3-methyl-1-(3-methyl-1-(1-...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370029((R)-5-Ethyl-2-fluoro-N-(3-methyl-1-(3-methyl-1-(4-...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370028((R)—N-(1-(1-(4-Bromophenyl)-3-methyl-4-oxo-1,...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370035((R)-2-Fluoro-N-(1-(1-(imidazo[1,2-a]pyridin-6-yl)-...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370034((R)-2-Fluoro-N-(3-methyl-1-(3-methyl-1-(4-(methyls...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370033((R)-2-Fluoro-N-(3-methyl-1-(3-methyl-1-(1-methyl-6...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370032((R)-5-Ethyl-2-fluoro-N-(3-methyl-1-(3-methyl-1-(3-...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370055((R)-4-(3-(2-(Dimethylamino)ethyl)-8-(2-(2-fluoro-5...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370054((R)—N-(1-(1-(4-(2H-Tetrazol-5-yl)phenyl)-3-me...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370053((R)—N-(1-(1-(4-(2H-Tetrazol-5-yl)phenyl)-3-me...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370052((R)—N-(1-(1-(4-(2H-Tetrazol-5-yl)phenyl)-3-me...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM369939((R)-2-Fluoro-N-(1-(1-(4-methoxyphenyl)-3-methyl-2,...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370058((R)—N-(1-(1-Cyclohexyl-3-methyl-2,4-dioxo-1,3...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370057((R)-2-Fluoro-N-(3-methyl-1-(3-methyl-2,4-dioxo-1-(...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370056((R)-4-(3-(2-(Dimethylamino)ethyl)-8-(2-(2-fluoro-5...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370047((R)—N-(1-(1-(4-(1H-1,2,4-Triazol-3-yl)phenyl)...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370046((R)-2-Fluoro-N-(3-methyl-1-(3-methyl-1-(4-(oxetan-...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370045((R)—N-(1-(1-(1H-Benzo[d]imidazol-6-yl)-3-meth...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370044((R)—N-(1-(1-(1H-Indazol-5-yl)-3-methyl-4-oxo-...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370051((R)—N-(1-(1-(4-(2H-Tetrazol-5-yl)phenyl)-3-me...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370050((R)-4-(8-(2-(2-Fluoro-5-(trifluoromethyl)benzamido...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370049((R)-4-(8-(2-(5-Cyclopropyl-2-fluorobenzamido)-3-me...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370048((R)-Methyl-4-(8-(2-(2-fluoro-5-(trifluoromethyl)be...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370061((R)—N-(1-(1-(Benzo[d]oxazol-5-yl)-3-methyl-2,...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370060((R)—N-(3-Methyl-1-(3-methyl-2,4-dioxo-1-(4-et...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM369910(US10233182, Example 6 | (R)-2-Fluoro-N-(1-(1-(3-fl...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM369909(US10233182, Example 5 | (R)—N-(1-(3-(Cyanomet...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM369906(US10233182, Example 4 | 2-Fluoro-3-methyl-N-((2R,3...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM369905(US10233182, Example 1 | (R)—N-(1-Cyclohexyl-2...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM369914(US10233182, Example 12 | (R)-2-Fluoro-N-(3-methyl-...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM369913(US10233182, Example 10 | (R)-2-Fluoro-N-(1-(1-(3-m...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM369912(US10233182, Example 8 | (R)—N-(1-(1-(3-Cyanop...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM369911(US10233182, Example 7 | (R)—N-(1-(1-(4-Cyanop...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM369927((R)—N-(1-(1-(1H-Benzo[d][1,2,3]triazol-5-yl)-...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM369926((R)-5-Ethyl-2-fluoro-N-(3-methyl-1-(3-methyl-2,4-d...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM369925((R)-2-Fluoro-N-(3-methyl-1-(3-methyl-2,4-dioxo-1-(...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM369924((R)-2-Fluoro-N-(3-methyl-1-(3-methyl-2,4-dioxo-1-(...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM369931(3-Fluoro-N-((2R,3R)-1-(1-(4-methoxyphenyl)-3-methy...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM369930(5-Ethyl-2-fluoro-N-((2R,3R)-3-methoxy-1-(1-(4-meth...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM369929((R)-5-Ethyl-2-fluoro-N-(3-methyl-1-(3-methyl-2,4-d...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM369928(5-Ethyl-2-fluoro-N-((2R,3S)-3-methoxy-1-(3-methyl-...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

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