Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 2587
TargetSodium channel protein type 5 subunit alpha(Human)
Parion Sciences

US Patent
LigandPNGBDBM372436(US10246425, Compound III-d | 3,5-diamino-N-(N-(4-(...)
Affinity DataIC50: 2.60nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
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Date in BDB:
12/30/2019
Entry Details
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TargetSodium channel protein type 5 subunit alpha(Human)
Parion Sciences

US Patent
LigandPNGBDBM372443(US10246425, Compound XVII-d)
Affinity DataIC50: 2.90nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
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Date in BDB:
12/30/2019
Entry Details
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TargetSodium channel protein type 5 subunit alpha(Human)
Parion Sciences

US Patent
LigandPNGBDBM372448(US10246425, Compound XI-cc | 3,5-diamino-N-(N-(4-(...)
Affinity DataIC50: 5.5nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetSodium channel protein type 5 subunit alpha(Human)
Parion Sciences

US Patent
LigandPNGBDBM372440(US10246425, Compound XIV-d | 3,5-diamino-N-(N-(4-(...)
Affinity DataIC50: 6nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetSodium channel protein type 5 subunit alpha(Human)
Parion Sciences

US Patent
LigandPNGBDBM372441(US10246425, Compound XV-dd | 3,5-diamino-N-(N-(4-(...)
Affinity DataIC50: 7.30nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
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Date in BDB:
12/30/2019
Entry Details
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TargetSodium channel protein type 5 subunit alpha(Human)
Parion Sciences

US Patent
LigandPNGBDBM372449(US10246425, Compound XII-d | 3,5-diamino-N-(N-(4-(...)
Affinity DataIC50: 8.40nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetSodium channel protein type 5 subunit alpha(Human)
Parion Sciences

US Patent
LigandPNGBDBM372445(US10246425, Compound VIII-d | 3,5-diamino-N-(N-(4-...)
Affinity DataIC50: 8.80nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetSodium channel protein type 5 subunit alpha(Human)
Parion Sciences

US Patent
LigandPNGBDBM372435(US10246425, Compound II-d | 3,5-diamino-N-(N-(4-(4...)
Affinity DataIC50: 10.6nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetSodium channel protein type 5 subunit alpha(Human)
Parion Sciences

US Patent
LigandPNGBDBM372447(US10246425, Compound IX-m | 3,5-diamino-N-(N-(4-(6...)
Affinity DataIC50: 11.3nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
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Date in BDB:
12/30/2019
Entry Details
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TargetSodium channel protein type 5 subunit alpha(Human)
Parion Sciences

US Patent
LigandPNGBDBM372439(US10246425, Compound XIII-bb | 3,5-diamino-N-(N-(4...)
Affinity DataIC50: 12.5nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetSodium channel protein type 5 subunit alpha(Human)
Parion Sciences

US Patent
LigandPNGBDBM372438(US10246425, Compound VI-d | 3,5-diamino-N-(N-(4-(4...)
Affinity DataIC50: 14.3nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
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Date in BDB:
12/30/2019
Entry Details
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TargetSodium channel protein type 5 subunit alpha(Human)
Parion Sciences

US Patent
LigandPNGBDBM372437(US10246425, Compound Vd | 3,5-diamino-N-(N-(4-(4-(...)
Affinity DataIC50: 24nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetSodium channel protein type 5 subunit alpha(Human)
Parion Sciences

US Patent
LigandPNGBDBM372446(US10246425, Compound X-d | 3,5-diamino-N-(N-(4-(6-...)
Affinity DataIC50: 27.4nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetSodium channel protein type 5 subunit alpha(Human)
Parion Sciences

US Patent
LigandPNGBDBM372442(US10246425, Compound XVI-ee)
Affinity DataIC50: 35.6nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetSodium channel protein type 5 subunit alpha(Human)
Parion Sciences

US Patent
LigandPNGBDBM372444(US10246425, Compound VIIee | 3,5-diamino-N-(N-(4-(...)
Affinity DataIC50: 40.8nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetSodium channel protein type 5 subunit alpha(Human)
Parion Sciences

US Patent
LigandPNGBDBM16173(3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-car...)
Affinity DataIC50: 781nMAssay Description:One assay used to assess mechanism of action and/or potency of the compounds of the present invention involves the determination of lumenal drug inhi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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