Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 3108
TargetEpidermal growth factor receptor [1-745,751-1210,T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391743(US10300058, Compound 28 | N-(3-((2-((2-methoxy-4-(...)
Affinity DataIC50: 0.800nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM149404(US8975249, I-4 | CO-1686 | Rociletinib | AVL-301 |...)
Affinity DataIC50: 1.30nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor [T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM149404(US8975249, I-4 | CO-1686 | Rociletinib | AVL-301 |...)
Affinity DataIC50: 1.30nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor [T790M,L858R](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391743(US10300058, Compound 28 | N-(3-((2-((2-methoxy-4-(...)
Affinity DataIC50: 1.5nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM149404(US8975249, I-4 | CO-1686 | Rociletinib | AVL-301 |...)
Affinity DataIC50: 2.10nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor [1-745,751-1210,T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391742(US10300058, Compound 27 | N-(3-((2-((2-methoxy-4-(...)
Affinity DataIC50: 3.60nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391733(US10300058, Compound 3 | N-(3-((2-((4-(1-acetyl-1,...)
Affinity DataIC50: 4.70nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391743(US10300058, Compound 28 | N-(3-((2-((2-methoxy-4-(...)
Affinity DataIC50: 5.5nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391731(US10300058, Compound 1 | pyrimidin-4-yl)amino)pyri...)
Affinity DataIC50: 5.70nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391732(US10300058, Compound 2 | acrylamide )
Affinity DataIC50: 6.20nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391735(US10300058, Compound 4 | N-(6-((2-((4-(1-acetylpip...)
Affinity DataIC50: 7.20nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391736(US10300058, Compound 5 | N-(6-((2-((4-(1-acetyl-1,...)
Affinity DataIC50: 8.90nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391742(US10300058, Compound 27 | N-(3-((2-((2-methoxy-4-(...)
Affinity DataIC50: 9.80nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-999,L858R](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391743(US10300058, Compound 28 | N-(3-((2-((2-methoxy-4-(...)
Affinity DataIC50: 11nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391734(US10300058, Compound 11 | N-(3-((2-((2-acetyl-7-me...)
Affinity DataIC50: 13nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391742(US10300058, Compound 27 | N-(3-((2-((2-methoxy-4-(...)
Affinity DataIC50: 36nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-999,L858R](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391742(US10300058, Compound 27 | N-(3-((2-((2-methoxy-4-(...)
Affinity DataIC50: 88nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM149404(US8975249, I-4 | CO-1686 | Rociletinib | AVL-301 |...)
Affinity DataIC50: 145nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM149404(US8975249, I-4 | CO-1686 | Rociletinib | AVL-301 |...)
Affinity DataIC50: 180nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM149404(US8975249, I-4 | CO-1686 | Rociletinib | AVL-301 |...)
Affinity DataIC50: 180nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor [T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391744(US10300058, Compound 29 | N-(3-((2-((2-methoxy-4-(...)
Affinity DataIC50: 320nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391731(US10300058, Compound 1 | pyrimidin-4-yl)amino)pyri...)
Affinity DataIC50: 323nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391735(US10300058, Compound 4 | N-(6-((2-((4-(1-acetylpip...)
Affinity DataIC50: 423nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391741(US10300058, Compound 26 | pyrimidin-4-yl)amino)phe...)
Affinity DataIC50: 510nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391732(US10300058, Compound 2 | acrylamide )
Affinity DataIC50: 552nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391734(US10300058, Compound 11 | N-(3-((2-((2-acetyl-7-me...)
Affinity DataIC50: 640nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391733(US10300058, Compound 3 | N-(3-((2-((4-(1-acetyl-1,...)
Affinity DataIC50: 699nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391736(US10300058, Compound 5 | N-(6-((2-((4-(1-acetyl-1,...)
Affinity DataIC50: 995nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391743(US10300058, Compound 28 | N-(3-((2-((2-methoxy-4-(...)
Affinity DataIC50: 1.20E+3nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391746(US10300058, Compound 41 | N-(3-((2-((2-methoxy-4-(...)
Affinity DataIC50: 1.40E+3nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM149404(US8975249, I-4 | CO-1686 | Rociletinib | AVL-301 |...)
Affinity DataIC50: 2.50E+3nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor [T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391747(US10300058, Compound 43 | N-(3-((2-((2-methoxy-4-(...)
Affinity DataIC50: 3.60E+3nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391739(US10300058, Compound 23 | methyl)pyrimidin-4-yl)am...)
Affinity DataIC50: 3.90E+3nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391737(US10300058, Compound 7 | N-(3-((2-((4-(8-acetyl-3,...)
Affinity DataIC50: 6.20E+3nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391740(US10300058, Compound 25 | N-(3-((2-((4-(1-(3-fluor...)
Affinity DataIC50: 7.10E+3nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391742(US10300058, Compound 27 | N-(3-((2-((2-methoxy-4-(...)
Affinity DataIC50: 9.60E+3nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391745(US10300058, Compound 37 | N-(3-((2-((2-acetyl-1,2,...)
Affinity DataIC50: 9.90E+3nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391744(US10300058, Compound 29 | N-(3-((2-((2-methoxy-4-(...)
Affinity DataIC50: 1.10E+4nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391738(US10300058, Compound 17 | N-(3-((2-((2-acetyl-8-me...)
Affinity DataIC50: 1.60E+4nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391741(US10300058, Compound 26 | pyrimidin-4-yl)amino)phe...)
Affinity DataIC50: 2.50E+4nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391743(US10300058, Compound 28 | N-(3-((2-((2-methoxy-4-(...)
Affinity DataIC50: 7.30E+4nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391746(US10300058, Compound 41 | N-(3-((2-((2-methoxy-4-(...)
Affinity DataIC50: 8.20E+4nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM149404(US8975249, I-4 | CO-1686 | Rociletinib | AVL-301 |...)
Affinity DataIC50: 1.53E+5nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391747(US10300058, Compound 43 | N-(3-((2-((2-methoxy-4-(...)
Affinity DataIC50: 1.59E+5nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391739(US10300058, Compound 23 | methyl)pyrimidin-4-yl)am...)
Affinity DataIC50: 2.94E+5nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391737(US10300058, Compound 7 | N-(3-((2-((4-(8-acetyl-3,...)
Affinity DataIC50: 3.32E+5nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391740(US10300058, Compound 25 | N-(3-((2-((4-(1-(3-fluor...)
Affinity DataIC50: 6.83E+5nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391742(US10300058, Compound 27 | N-(3-((2-((2-methoxy-4-(...)
Affinity DataIC50: 8.71E+5nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391745(US10300058, Compound 37 | N-(3-((2-((2-acetyl-1,2,...)
Affinity DataIC50: 1.28E+6nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391738(US10300058, Compound 17 | N-(3-((2-((2-acetyl-8-me...)
Affinity DataIC50: 1.37E+6nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent