Compile Data Set for Download or QSAR
Report error Found 252 Enz. Inhib. hit(s) with all data for entry = 3144
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus)
Mutabilis

US Patent
LigandPNGBDBM392802(7-(1-cyclohexylbenzimidazol-5-yl)-5-[[(2R)-1-methy...)
Affinity DataIC50: 0.400nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus)
Mutabilis

US Patent
LigandPNGBDBM392796(5-[[(2R)-1-methylpyrrolidin-2-yl]methoxy]-7-(1-tet...)
Affinity DataIC50: 0.800nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus)
Mutabilis

US Patent
LigandPNGBDBM392744(7-(1-Cyclohexyl-1H-benzimidazol-5-yl)-5-(hexahydro...)
Affinity DataIC50: 1.40nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
Mutabilis

US Patent
LigandPNGBDBM392796(5-[[(2R)-1-methylpyrrolidin-2-yl]methoxy]-7-(1-tet...)
Affinity DataIC50: 1.40nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
Mutabilis

US Patent
LigandPNGBDBM392802(7-(1-cyclohexylbenzimidazol-5-yl)-5-[[(2R)-1-methy...)
Affinity DataIC50: 1.40nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecium E1679)
Mutabilis

US Patent
LigandPNGBDBM392794(5-[4,4-bis(hydroxymethyl)-1-piperidyl]-7-(1-cycloh...)
Affinity DataIC50: 2nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
Mutabilis

US Patent
LigandPNGBDBM392769(1′-Cyclohexyl-6-[methyl-(2-pyrrolidin-1-yl-e...)
Affinity DataIC50: 2.90nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecium E1679)
Mutabilis

US Patent
LigandPNGBDBM392802(7-(1-cyclohexylbenzimidazol-5-yl)-5-[[(2R)-1-methy...)
Affinity DataIC50: 3.60nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus)
Mutabilis

US Patent
LigandPNGBDBM392795(7-[1-[(1R,2R)-2-fluorocyclohexyl]benzimidazol-5-yl...)
Affinity DataIC50: 4nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
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TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
Mutabilis

US Patent
LigandPNGBDBM392795(7-[1-[(1R,2R)-2-fluorocyclohexyl]benzimidazol-5-yl...)
Affinity DataIC50: 4nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
Mutabilis

US Patent
LigandPNGBDBM392774(rac-1′-((trans)-3-methyl-cyclohexyl)-6-[meth...)
Affinity DataIC50: 4.30nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
Mutabilis

US Patent
LigandPNGBDBM392785(7-(3,4-Dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-(2-...)
Affinity DataIC50: 4.5nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
Mutabilis

US Patent
LigandPNGBDBM392801(7-(3,4-dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-[(1...)
Affinity DataIC50: 4.70nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus)
Mutabilis

US Patent
LigandPNGBDBM392785(7-(3,4-Dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-(2-...)
Affinity DataIC50: 4.80nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
Mutabilis

US Patent
LigandPNGBDBM392793(7-(3,4-dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-[[(...)
Affinity DataIC50: 5.10nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
Mutabilis

US Patent
LigandPNGBDBM392779(1′-(2,2-Difluoro-ethyl)-6-[(2-dimethylamino-...)
Affinity DataIC50: 5.40nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus)
Mutabilis

US Patent
LigandPNGBDBM392774(rac-1′-((trans)-3-methyl-cyclohexyl)-6-[meth...)
Affinity DataIC50: 5.70nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecium E1679)
Mutabilis

US Patent
LigandPNGBDBM392796(5-[[(2R)-1-methylpyrrolidin-2-yl]methoxy]-7-(1-tet...)
Affinity DataIC50: 5.70nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus)
Mutabilis

US Patent
LigandPNGBDBM392793(7-(3,4-dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-[[(...)
Affinity DataIC50: 6.20nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus)
Mutabilis

US Patent
LigandPNGBDBM392801(7-(3,4-dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-[(1...)
Affinity DataIC50: 6.5nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
Mutabilis

US Patent
LigandPNGBDBM392781(1′-((1R,2R)-2-Fluoro-cyclohexyl)-6-[(2-hydro...)
Affinity DataIC50: 6.70nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus)
Mutabilis

US Patent
LigandPNGBDBM392786(6-(2-Dimethylamino-ethoxy)-1′-ethyl-1H,1R...)
Affinity DataIC50: 6.80nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
Mutabilis

US Patent
LigandPNGBDBM392794(5-[4,4-bis(hydroxymethyl)-1-piperidyl]-7-(1-cycloh...)
Affinity DataIC50: 6.80nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus)
Mutabilis

US Patent
LigandPNGBDBM392767(6-[(2-dimethylamino-ethyl)-methyl-amino]-1′-...)
Affinity DataIC50: 6.90nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
Mutabilis

US Patent
LigandPNGBDBM392789(7-(1-butylbenzimidazol-5-yl)-5-[2-(dimethylamino)e...)
Affinity DataIC50: 7.30nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
Mutabilis

US Patent
LigandPNGBDBM392778(1′-(4,4-Difluoro-cyclohexyl)-6-[(2-dimethyla...)
Affinity DataIC50: 8.10nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
Mutabilis

US Patent
LigandPNGBDBM392767(6-[(2-dimethylamino-ethyl)-methyl-amino]-1′-...)
Affinity DataIC50: 8.20nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
Mutabilis

US Patent
LigandPNGBDBM392786(6-(2-Dimethylamino-ethoxy)-1′-ethyl-1H,1R...)
Affinity DataIC50: 8.30nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
Mutabilis

US Patent
LigandPNGBDBM392797(7-(3,4-dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-[3-...)
Affinity DataIC50: 9nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
Mutabilis

US Patent
LigandPNGBDBM392784(7-(3,4-Dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-[me...)
Affinity DataIC50: 9.20nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
Mutabilis

US Patent
LigandPNGBDBM392791(5-[2-(dimethylamino)ethyl-methyl-amino]-7-[6-(dime...)
Affinity DataIC50: 9.20nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus)
Mutabilis

US Patent
LigandPNGBDBM392742({1-[7-(1-Cyclohexyl-1H-benzimidazol-5-yl)-3H-imida...)
Affinity DataIC50: 11nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus)
Mutabilis

US Patent
LigandPNGBDBM392746({1-[4-(1-Cyclohexyl-1H-benzimidazol-5-yl)-1H-imida...)
Affinity DataIC50: 12nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
Mutabilis

US Patent
LigandPNGBDBM392790(5-[2-(dimethylamino)ethyl-methyl-amino]-7-(1-pheny...)
Affinity DataIC50: 12nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus)
Mutabilis

US Patent
LigandPNGBDBM392777(6-[(2-Dimethylamino-ethyl)-methyl-amino]-1′-...)
Affinity DataIC50: 13nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus)
Mutabilis

US Patent
LigandPNGBDBM392778(1′-(4,4-Difluoro-cyclohexyl)-6-[(2-dimethyla...)
Affinity DataIC50: 13nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus)
Mutabilis

US Patent
LigandPNGBDBM392779(1′-(2,2-Difluoro-ethyl)-6-[(2-dimethylamino-...)
Affinity DataIC50: 14nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
Mutabilis

US Patent
LigandPNGBDBM392775(1′-Ethyl-6-[methyl-(2-methylamino-ethyl)-ami...)
Affinity DataIC50: 15nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus)
Mutabilis

US Patent
LigandPNGBDBM392781(1′-((1R,2R)-2-Fluoro-cyclohexyl)-6-[(2-hydro...)
Affinity DataIC50: 15nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
Mutabilis

US Patent
LigandPNGBDBM392765(1′-Cyclohexyl-6-[(2-hydroxy-ethyl)-methyl-am...)
Affinity DataIC50: 16nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus)
Mutabilis

US Patent
LigandPNGBDBM392775(1′-Ethyl-6-[methyl-(2-methylamino-ethyl)-ami...)
Affinity DataIC50: 16nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
Mutabilis

US Patent
LigandPNGBDBM392777(6-[(2-Dimethylamino-ethyl)-methyl-amino]-1′-...)
Affinity DataIC50: 16nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus)
Mutabilis

US Patent
LigandPNGBDBM392773(6-[(2-Dimethylamino-ethyl)-methyl-amino]-1′-...)
Affinity DataIC50: 17nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
Mutabilis

US Patent
LigandPNGBDBM392776(7-(3,4-Dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-[(2...)
Affinity DataIC50: 17nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus)
Mutabilis

US Patent
LigandPNGBDBM392790(5-[2-(dimethylamino)ethyl-methyl-amino]-7-(1-pheny...)
Affinity DataIC50: 17nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
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TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
Mutabilis

US Patent
LigandPNGBDBM392738((3R,4R)-1-[7-(1-Cyclohexyl-1H-benzimidazol-5-yl)-3...)
Affinity DataIC50: 18nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
Mutabilis

US Patent
LigandPNGBDBM392742({1-[7-(1-Cyclohexyl-1H-benzimidazol-5-yl)-3H-imida...)
Affinity DataIC50: 18nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
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TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
Mutabilis

US Patent
LigandPNGBDBM392763(1′-Cyclohexyl-6-(4-methyl-piperazin-1-yl)-1H...)
Affinity DataIC50: 18nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
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TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecium E1679)
Mutabilis

US Patent
LigandPNGBDBM392769(1′-Cyclohexyl-6-[methyl-(2-pyrrolidin-1-yl-e...)
Affinity DataIC50: 18nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
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TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
Mutabilis

US Patent
LigandPNGBDBM392744(7-(1-Cyclohexyl-1H-benzimidazol-5-yl)-5-(hexahydro...)
Affinity DataIC50: 19nMAssay Description:The assay buffer AB contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The following...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

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