Compile Data Set for Download or QSAR
Report error Found 104 Enz. Inhib. hit(s) with all data for entry = 8628
TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408950(Methyl 1-(2-cyclobutyl-N-((4'-methoxy-3'- methyl-[...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408951(Methyl 1-(2-cyclopropyl-N-((4'-methoxy-3'- methyl-...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408944(Methyl 1-(N-((4'-methoxy-3'-methyl-[1,1'- biphenyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408947(Methyl 1-(N-((4'-methoxy-3'-methyl-[1,1'- biphenyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408940(Isopropyl 1-(N-((4′-methoxy-3′-methyl-...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408941(Methyl 1-(N-((4'-methoxy-3'-methyl-[1,1'- biphenyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408942(Methyl 1-(N-((4'-methoxy-3'-methyl-[1,1'- biphenyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408943(Methyl 1-(2-cyclopentyl-N-((4'-methoxy-3'- methyl-...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408935(Methyl 1-(trans-4-hydroxy-N-((4'-methoxy-3'- methy...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408936(Methyl 1-(trans-N- ((3'-chloro-4'-methoxy-[1,1'- b...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408939(Isopropyl 1-(N-((3'-cyano-4'-methoxy-[1,1'- biphen...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408964(Methyl 1-(N-((trans-4-(3- methoxyphenyl) cyclohexy...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408965(Methyl 1-(N-((trans-4-(4- methoxyphenyl) cyclohexy...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408967(Methyl 1-(N-((trans-4-(4-methoxy-3- methylphenyl) ...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408961(Methyl 1-(3,3-dimethyl-N-((trans-4-(m- tolyl)cyclo...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408962(Methyl 1-(3,3-dimethyl-N-((trans-4-(p- tolyl)cyclo...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408958(Isopropyl 1-(N-((trans-4-(4-methoxy-3-methylphenyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408959(Isopropyl 1-(N-((trans-4-(4-methoxy-3- methylpheny...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408952(Methyl 1-(N-((4'-methoxy-3'-methyl-[1,1'- biphenyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408953(Methyl 1-(N-((4'-methoxy-3'-methyl-[1,1'- biphenyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408968(Methyl 1-(N-((trans-4-(4-methoxy-3- methylphenyl) ...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408970(Methyl 1-(trans-4-hydroxy-N-((trans-4-(4- methoxy-...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408882(Methyl 1-(N-((4'-(dimethylamino)-[1,1'- biphenyl]-...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408870((E)-Methyl 3-(2-(N-((4′-(dimethylamino)-[1,1...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408898(Methyl 1-(N- ((2',3'-difluoro-4'-methoxy- [1,1'-bi...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408899(Methyl 1-(N-((3'-cyano-4'-methyl-[1,1'- biphenyl]-...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408900(Methyl 1-(N-((3'-chloro-4'-cyano-[1,1'- biphenyl]-...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408894(Methyl 1-(N-((4'-methoxy-3'- methyl-[1,1'-biphenyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408895(Methyl 1-(N-((2-cyano-4'-methoxy-3'- methyl- [1,1'...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408897(Methyl 1-(N-((4'-methoxy-3'-methyl- [1,1'-biphenyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408890(Ethyl 1-(N-((4'-methoxy-3'-methyl-[1,1'- biphenyl]...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408891(Isopropyl 1-(N-((4'-methoxy-3'-methyl-[1,1'- biphe...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408893(Methyl 1-(N-((3'-cyano-4'-methoxy-[1,1'- biphenyl]...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408887((E)-Methyl 3-(2-(N-((trans-4-(4-methoxy-3-methylph...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408888(Methyl 1-(N-((4′-methoxy-3′-methyl-[1,...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408889(Methyl 1-(N-((4'-methoxy-3'-methyl-[1,1'- biphenyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408915(Methyl 1-(N-((4'-methoxy-[1,1'-biphenyl]-4- yl)met...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408916(Methyl 1-(N-(4-(2,3-dihydrobenzofuran-5- yl)benzyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408917(Methyl 1-(N-(4-(2,3-dihydrobenzofuran-6- yl)benzyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408918(Methyl 1-(N-(4-(2,3- dihydrobenzo[b][1,4] dioxin-6...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408911(Methyl 1-(N-((3'-chloro-4'-(trifluoromethoxy)- [1,...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408912(Methyl 1-(N-((4'-cyano-3'-methyl-[1,1'- biphenyl]-...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408914(Methyl 1-(3,3-dimethyl-N-(4-(1-methyl-1H- indol-5-...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408906(Methyl 1-(N-(4-(6-methoxy-5-methylpyridin-3- yl)be...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408908(Methyl 1-(N-(4-(6-(dimethylamino)pyridin-3- yl)ben...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408910(Methyl 1-(N-((4'-cyclopropyl-[1,1'-biphenyl]-4- yl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408903(Methyl 1-(N-(4-(2,2- difluorobenzo[d][1,3] dioxol-...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408904(Methyl 1-(N-(4-(5-fluoro-6- methoxypyridin-3- yl)b...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408905(Methyl 1-(N-(4-(5-chloro-6- methoxypyridin-3- yl)b...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408931(Methyl 1-(N-((4'-(2-hydroxyethyl)-[1,1'- biphenyl]...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

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