Compile Data Set for Download or QSAR
Report error Found 161 Enz. Inhib. hit(s) with all data for entry = 8948
LigandPNGBDBM430635(US10550102, Example (-)-1. b))
Affinity DataEC50:  10nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
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Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430642(US10550102, Example 7a)
Affinity DataEC50:  0.5nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430649(US10550102, Example (+)-1. b))
Affinity DataEC50:  0.5nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430673(US10550102, Example 7b)
Affinity DataEC50:  2.40nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
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Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430678(Example 2-A. (+)-(S)-Ethyl-1-(3-(3-(4-(1-(cyclopro...)
Affinity DataEC50:  1nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430679(US10550102, Example (-)-8. b))
Affinity DataEC50:  53nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430739(US10550102, Example 3a)
Affinity DataEC50:  1nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430740(US10550102, Example (+)-8. b))
Affinity DataEC50:  0.5nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430859(US10550102, Example 3b)
Affinity DataEC50:  6.90nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
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Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430860(US10550102, Example 9. b). (-))
Affinity DataEC50:  184nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430861(US10550102, Example 4a)
Affinity DataEC50:  2.40nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430862(US10550102, Example 9. b). (+))
Affinity DataEC50:  0.5nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430863(US10550102, Example 4b)
Affinity DataEC50:  116nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430864(US10550102, Example 10a)
Affinity DataEC50:  0.5nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430865(US10550102, Example 5-1)
Affinity DataEC50:  39nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430866(US10550102, Example 10b)
Affinity DataEC50:  49nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430867(US10550102, Example 5-2)
Affinity DataEC50:  1nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430868(US10550102, Example 11-1)
Affinity DataEC50:  1nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430869(US10550102, Example 5-3)
Affinity DataEC50:  0.5nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430870(US10550102, Example 11-2)
Affinity DataEC50:  1nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430871(US10550102, Example 5-4)
Affinity DataEC50:  2nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430872(US10550102, Example 11-3)
Affinity DataEC50:  1.40nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430873(US10550102, Example 5-5)
Affinity DataEC50:  2.40nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430874(US10550102, Example 11-4)
Affinity DataEC50:  0.5nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430875(US10550102, Example 5-6)
Affinity DataEC50:  0.5nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430876(Example 12-A. tert-Butyl 4-(4-((7-(6-(4-(ethoxycar...)
Affinity DataEC50:  1nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430877(US10550102, Example 5-7)
Affinity DataEC50:  0.5nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430878(Example 13-A. tert-Butyl 4-(4-((7-(6-(4-(ethoxycar...)
Affinity DataEC50:  0.5nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430879(US10550102, Example 5-8)
Affinity DataEC50:  1nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430880(Example 14-A. tert-Butyl 4-(4-((7-(6-(4-(ethoxycar...)
Affinity DataEC50:  0.5nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430881(US10550102, Example 5-9)
Affinity DataEC50:  0.5nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430882(Example 15-A. Ethyl 1-(6-(1-(3-ethyl-4-1-(2,2,2-tr...)
Affinity DataEC50:  1.5nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430883(US10550102, Example 6. b). (+))
Affinity DataEC50:  0.5nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430884(Example 16-A. Ethyl 5-ethyl-1-(6-(1-(3-ethyl-4-(2,...)
Affinity DataEC50:  3.5nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430885(US10550102, Example 6. b). (-))
Affinity DataEC50:  24nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430886(US10550102, Example 45a)
Affinity DataEC50:  0.5nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430887(US10550102, Example 5-10)
Affinity DataEC50:  0.5nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430888(US10550102, Example 45b)
Affinity DataEC50:  3.5nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430889(US10550102, Example 17a)
Affinity DataEC50:  0.5nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430890(US10550102, Example (+)-46-1)
Affinity DataEC50:  0.5nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430891(US10550102, Example 17b)
Affinity DataEC50:  0.5nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430892(US10550102, Example (-)-46-1)
Affinity DataEC50:  100nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430893(US10550102, Example 18)
Affinity DataEC50:  1.40nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430894(US10550102, Example (+)-46-2)
Affinity DataEC50:  1nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430895(US10550102, Example 19a)
Affinity DataEC50:  0.5nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430896(US10550102, Example (-)-46-2)
Affinity DataEC50:  160nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430897(US10550102, Example 19b)
Affinity DataEC50:  0.5nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430898(US10550102, Example (+)-46-3)
Affinity DataEC50:  1nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430899(US10550102, Example (+)-20-1)
Affinity DataEC50:  0.5nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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LigandPNGBDBM430900(US10550102, Example (-)-46-3)
Affinity DataEC50:  303nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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