Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 9033
TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Neupharma

US Patent
LigandPNGBDBM436180(US10590106, Compound C003)
Affinity DataIC50: 100nMAssay Description:Inhibitory activities Inhibitory activities of compounds against BRAF, and BRAF V600E were measured by Invitrogen using Z′-LYTE Method as brief...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Neupharma

US Patent
LigandPNGBDBM436176(US10590106, Compound C001)
Affinity DataIC50: 100nMAssay Description:Inhibitory activities Inhibitory activities of compounds against BRAF, and BRAF V600E were measured by Invitrogen using Z′-LYTE Method as brief...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Neupharma

US Patent
LigandPNGBDBM436181(US10590106, Compound C075)
Affinity DataIC50: 100nMAssay Description:Inhibitory activities Inhibitory activities of compounds against BRAF, and BRAF V600E were measured by Invitrogen using Z′-LYTE Method as brief...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Neupharma

US Patent
LigandPNGBDBM436179(US10590106, Compound C009)
Affinity DataIC50: 100nMAssay Description:Inhibitory activities Inhibitory activities of compounds against BRAF, and BRAF V600E were measured by Invitrogen using Z′-LYTE Method as brief...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Neupharma

US Patent
LigandPNGBDBM436182(US10590106, Compound C069)
Affinity DataIC50: 100nMAssay Description:Inhibitory activities Inhibitory activities of compounds against BRAF, and BRAF V600E were measured by Invitrogen using Z′-LYTE Method as brief...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Neupharma

US Patent
LigandPNGBDBM436174(US10590109, Compound 1)
Affinity DataIC50: 100nMAssay Description:Inhibitory activities Inhibitory activities of compounds against BRAF, and BRAF V600E were measured by Invitrogen using Z′-LYTE Method as brief...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2020
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Neupharma

US Patent
LigandPNGBDBM436181(US10590106, Compound C075)
Affinity DataIC50: 100nMAssay Description:Inhibitory activities of compounds against KDR (VEGFR2) were also measured by Invitrogen using Z'-LYTE Method as described above with the following m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2020
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Neupharma

US Patent
LigandPNGBDBM436179(US10590106, Compound C009)
Affinity DataIC50: 100nMAssay Description:Inhibitory activities of compounds against KDR (VEGFR2) were also measured by Invitrogen using Z'-LYTE Method as described above with the following m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2020
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Neupharma

US Patent
LigandPNGBDBM436180(US10590106, Compound C003)
Affinity DataIC50: 100nMAssay Description:Inhibitory activities of compounds against KDR (VEGFR2) were also measured by Invitrogen using Z'-LYTE Method as described above with the following m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2020
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Neupharma

US Patent
LigandPNGBDBM436176(US10590106, Compound C001)
Affinity DataIC50: 100nMAssay Description:Inhibitory activities of compounds against KDR (VEGFR2) were also measured by Invitrogen using Z'-LYTE Method as described above with the following m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2020
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Neupharma

US Patent
LigandPNGBDBM436174(US10590109, Compound 1)
Affinity DataIC50: 100nMAssay Description:Inhibitory activities of compounds against KDR (VEGFR2) were also measured by Invitrogen using Z'-LYTE Method as described above with the following m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2020
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Neupharma

US Patent
LigandPNGBDBM436182(US10590106, Compound C069)
Affinity DataIC50: 100nMAssay Description:Inhibitory activities of compounds against KDR (VEGFR2) were also measured by Invitrogen using Z'-LYTE Method as described above with the following m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2020
Entry Details
US Patent