Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 9451
TargetTyrosine-protein kinase JAK1(Human)
Aclaris Therapeutics

US Patent
LigandPNGBDBM466940(propyl (R)-4-(1-(2-cyano-1-cyclopentylethyl)-1H-py...)
Affinity DataIC50: 10nMAssay Description:The activity of JAK3 (a.a. 781-1124, ThermoFisher) was quantified by measuring the phosphorylation of SRCtide (FAM-GEEPLYWSFPAKKK-NH2). Kinase reacti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Aclaris Therapeutics

US Patent
LigandPNGBDBM466938(isopropyl 4-(1-(2-cyano-1-cyclopentylethyl)-1H-pyr...)
Affinity DataIC50: 10nMAssay Description:The activity of JAK3 (a.a. 781-1124, ThermoFisher) was quantified by measuring the phosphorylation of SRCtide (FAM-GEEPLYWSFPAKKK-NH2). Kinase reacti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Aclaris Therapeutics

US Patent
LigandPNGBDBM466936(ethyl 4-(1-(2-cyano-1-cyclopentylethyl)-1H-pyrazol...)
Affinity DataIC50: 10nMAssay Description:The activity of JAK3 (a.a. 781-1124, ThermoFisher) was quantified by measuring the phosphorylation of SRCtide (FAM-GEEPLYWSFPAKKK-NH2). Kinase reacti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Aclaris Therapeutics

US Patent
LigandPNGBDBM466935(ethyl 4-(1-(3-(cyanomethyl)-1-(ethylsulfonyl)azeti...)
Affinity DataIC50: 10nMAssay Description:The activity of JAK3 (a.a. 781-1124, ThermoFisher) was quantified by measuring the phosphorylation of SRCtide (FAM-GEEPLYWSFPAKKK-NH2). Kinase reacti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Aclaris Therapeutics

US Patent
LigandPNGBDBM466934(ethyl 4-(1-(2-cyano-1-cyclopentylethyl)-1H-pyrazol...)
Affinity DataIC50: 10nMAssay Description:The activity of JAK3 (a.a. 781-1124, ThermoFisher) was quantified by measuring the phosphorylation of SRCtide (FAM-GEEPLYWSFPAKKK-NH2). Kinase reacti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Aclaris Therapeutics

US Patent
LigandPNGBDBM466939(isopropyl 4-(1-(2-cyano-1-cyclopentylethyl)-1H-pyr...)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Aclaris Therapeutics

US Patent
LigandPNGBDBM466938(isopropyl 4-(1-(2-cyano-1-cyclopentylethyl)-1H-pyr...)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Aclaris Therapeutics

US Patent
LigandPNGBDBM466939(isopropyl 4-(1-(2-cyano-1-cyclopentylethyl)-1H-pyr...)
Affinity DataIC50: 55nMAssay Description:The activity of JAK3 (a.a. 781-1124, ThermoFisher) was quantified by measuring the phosphorylation of SRCtide (FAM-GEEPLYWSFPAKKK-NH2). Kinase reacti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Aclaris Therapeutics

US Patent
LigandPNGBDBM466937(ethyl 4-(1-(2-cyano-1-cyclopentylethyl)-1H-pyrazol...)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Aclaris Therapeutics

US Patent
LigandPNGBDBM466936(ethyl 4-(1-(2-cyano-1-cyclopentylethyl)-1H-pyrazol...)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Aclaris Therapeutics

US Patent
LigandPNGBDBM466937(ethyl 4-(1-(2-cyano-1-cyclopentylethyl)-1H-pyrazol...)
Affinity DataIC50: 55nMAssay Description:The activity of JAK3 (a.a. 781-1124, ThermoFisher) was quantified by measuring the phosphorylation of SRCtide (FAM-GEEPLYWSFPAKKK-NH2). Kinase reacti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Aclaris Therapeutics

US Patent
LigandPNGBDBM466935(ethyl 4-(1-(3-(cyanomethyl)-1-(ethylsulfonyl)azeti...)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Aclaris Therapeutics

US Patent
LigandPNGBDBM466934(ethyl 4-(1-(2-cyano-1-cyclopentylethyl)-1H-pyrazol...)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Aclaris Therapeutics

US Patent
LigandPNGBDBM466940(propyl (R)-4-(1-(2-cyano-1-cyclopentylethyl)-1H-py...)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent