Compile Data Set for Download or QSAR
Report error Found 68 Enz. Inhib. hit(s) with all data for entry = 9472
TargetDipeptidyl peptidase 4(Mouse)
Eli Lilly

US Patent
LigandPNGBDBM468963(1-[1-[(3R,5S,6R)-5-Amino-6-(2,5-difluorophenyl)tet...)
Affinity DataIC50: 0.474nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Mouse)
Eli Lilly

US Patent
LigandPNGBDBM468964(1-[1-[(3R,5S,6R)-5-Amino-6-(2,5-difluorophenyl)tet...)
Affinity DataIC50: 0.498nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Mouse)
Eli Lilly

US Patent
LigandPNGBDBM468972((3S)-1-[2-[(3R,5S,6R)-5-Amino-6-(2,5-difluoropheny...)
Affinity DataIC50: 0.564nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
Eli Lilly

US Patent
LigandPNGBDBM468975(1-[2-[(3R,5S,6R)-5-Amino-6- (2,5- difluorophenyl)t...)
Affinity DataIC50: 1.52nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Mouse)
Eli Lilly

US Patent
LigandPNGBDBM468975(1-[2-[(3R,5S,6R)-5-Amino-6- (2,5- difluorophenyl)t...)
Affinity DataIC50: 1.52nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Mouse)
Eli Lilly

US Patent
LigandPNGBDBM468974(1-[2-[(3R,5S,6R)-5-Amino-6- (2,5- difluorophenyl)t...)
Affinity DataIC50: 1.52nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
Eli Lilly

US Patent
LigandPNGBDBM468972((3S)-1-[2-[(3R,5S,6R)-5-Amino-6-(2,5-difluoropheny...)
Affinity DataIC50: 1.67nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
Eli Lilly

US Patent
LigandPNGBDBM468964(1-[1-[(3R,5S,6R)-5-Amino-6-(2,5-difluorophenyl)tet...)
Affinity DataIC50: 1.88nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
Eli Lilly

US Patent
LigandPNGBDBM468963(1-[1-[(3R,5S,6R)-5-Amino-6-(2,5-difluorophenyl)tet...)
Affinity DataIC50: 1.91nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Mouse)
Eli Lilly

US Patent
LigandPNGBDBM468977(1-[2-[(3R,5S,6R)-5-Aamino- 6-(2,5- difluorophenyl)...)
Affinity DataIC50: 2.03nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Mouse)
Eli Lilly

US Patent
LigandPNGBDBM468976((3S)-1-[1-[(3R,5S,6R)-5-Amino-6-(2,5-difluoropheny...)
Affinity DataIC50: 2.64nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
Eli Lilly

US Patent
LigandPNGBDBM468973(1-[2-[(3R,5S,6R)-5-Amino-6- (2,5- difluorophenyl)t...)
Affinity DataIC50: 2.71nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
Eli Lilly

US Patent
LigandPNGBDBM468974(1-[2-[(3R,5S,6R)-5-Amino-6- (2,5- difluorophenyl)t...)
Affinity DataIC50: 2.96nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
Eli Lilly

US Patent
LigandPNGBDBM468957(1-[2-[(3R,5S,6R)-5-Amino-6-(2,5-difluorophenyl)tet...)
Affinity DataIC50: 2.98nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
Eli Lilly

US Patent
LigandPNGBDBM468977(1-[2-[(3R,5S,6R)-5-Aamino- 6-(2,5- difluorophenyl)...)
Affinity DataIC50: 3.27nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
Eli Lilly

US Patent
LigandPNGBDBM468976((3S)-1-[1-[(3R,5S,6R)-5-Amino-6-(2,5-difluoropheny...)
Affinity DataIC50: 3.43nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Mouse)
Eli Lilly

US Patent
LigandPNGBDBM468973(1-[2-[(3R,5S,6R)-5-Amino-6- (2,5- difluorophenyl)t...)
Affinity DataIC50: 3.57nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
Eli Lilly

US Patent
LigandPNGBDBM468958(1-[2-[(3R,5S,6R)-5-Amino- 6-(2,5- difluorophenyl)t...)
Affinity DataIC50: 3.67nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
Eli Lilly

US Patent
LigandPNGBDBM468979(1-[1-[(3R,5S,6R)-5-Amino- 6-(2,5- difluorophenyl)t...)
Affinity DataIC50: 6.23nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Mouse)
Eli Lilly

US Patent
LigandPNGBDBM468958(1-[2-[(3R,5S,6R)-5-Amino- 6-(2,5- difluorophenyl)t...)
Affinity DataIC50: 6.46nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Mouse)
Eli Lilly

US Patent
LigandPNGBDBM468957(1-[2-[(3R,5S,6R)-5-Amino-6-(2,5-difluorophenyl)tet...)
Affinity DataIC50: 6.53nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
Eli Lilly

US Patent
LigandPNGBDBM468980(1-[1-[(3R,5S,6R)-5-Amino- 6-(2,5- difluorophenyl)t...)
Affinity DataIC50: 6.76nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
Eli Lilly

US Patent
LigandPNGBDBM468978(1-[1-[(3R,5S,6R)-5-Amino-6- (2,5- difluorophenyl)t...)
Affinity DataIC50: 7.56nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Mouse)
Eli Lilly

US Patent
LigandPNGBDBM468979(1-[1-[(3R,5S,6R)-5-Amino- 6-(2,5- difluorophenyl)t...)
Affinity DataIC50: 7.73nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Mouse)
Eli Lilly

US Patent
LigandPNGBDBM468977(1-[2-[(3R,5S,6R)-5-Aamino- 6-(2,5- difluorophenyl)...)
Affinity DataIC50: 10.6nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Mouse)
Eli Lilly

US Patent
LigandPNGBDBM468975(1-[2-[(3R,5S,6R)-5-Amino-6- (2,5- difluorophenyl)t...)
Affinity DataIC50: 12.8nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Mouse)
Eli Lilly

US Patent
LigandPNGBDBM468978(1-[1-[(3R,5S,6R)-5-Amino-6- (2,5- difluorophenyl)t...)
Affinity DataIC50: 13.1nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
Eli Lilly

US Patent
LigandPNGBDBM468981((3S)-1-[2-[1-[(3R,5S,6R)-5-Amino-6-(2,5-difluoroph...)
Affinity DataIC50: 14.7nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Eli Lilly

US Patent
LigandPNGBDBM468977(1-[2-[(3R,5S,6R)-5-Aamino- 6-(2,5- difluorophenyl)...)
Affinity DataIC50: 15nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
Eli Lilly

US Patent
LigandPNGBDBM468959(1-[2-[4-[(3R,5S,6R)-5-Amino-6-(2,5-difluorophenyl)...)
Affinity DataIC50: 16.4nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
Eli Lilly

US Patent
LigandPNGBDBM468960(1-[2-[4-[(3R,5S,6R)-5- Amino-6-(2,5- difluoropheny...)
Affinity DataIC50: 16.5nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
Eli Lilly

US Patent
LigandPNGBDBM468961((3S)-1-[6-[4-[(3S,5S,6R)-5-Amino-6-(2,5-difluoroph...)
Affinity DataIC50: 17.5nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Mouse)
Eli Lilly

US Patent
LigandPNGBDBM468980(1-[1-[(3R,5S,6R)-5-Amino- 6-(2,5- difluorophenyl)t...)
Affinity DataIC50: 18.6nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Eli Lilly

US Patent
LigandPNGBDBM468975(1-[2-[(3R,5S,6R)-5-Amino-6- (2,5- difluorophenyl)t...)
Affinity DataIC50: 20.8nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Mouse)
Eli Lilly

US Patent
LigandPNGBDBM468957(1-[2-[(3R,5S,6R)-5-Amino-6-(2,5-difluorophenyl)tet...)
Affinity DataIC50: 21.9nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Mouse)
Eli Lilly

US Patent
LigandPNGBDBM468981((3S)-1-[2-[1-[(3R,5S,6R)-5-Amino-6-(2,5-difluoroph...)
Affinity DataIC50: 25.5nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Mouse)
Eli Lilly

US Patent
LigandPNGBDBM468961((3S)-1-[6-[4-[(3S,5S,6R)-5-Amino-6-(2,5-difluoroph...)
Affinity DataIC50: 28.3nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Mouse)
Eli Lilly

US Patent
LigandPNGBDBM468978(1-[1-[(3R,5S,6R)-5-Amino-6- (2,5- difluorophenyl)t...)
Affinity DataIC50: 29.2nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Mouse)
Eli Lilly

US Patent
LigandPNGBDBM468979(1-[1-[(3R,5S,6R)-5-Amino- 6-(2,5- difluorophenyl)t...)
Affinity DataIC50: 30.5nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Mouse)
Eli Lilly

US Patent
LigandPNGBDBM468960(1-[2-[4-[(3R,5S,6R)-5- Amino-6-(2,5- difluoropheny...)
Affinity DataIC50: 30.7nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Mouse)
Eli Lilly

US Patent
LigandPNGBDBM468976((3S)-1-[1-[(3R,5S,6R)-5-Amino-6-(2,5-difluoropheny...)
Affinity DataIC50: 32.1nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Mouse)
Eli Lilly

US Patent
LigandPNGBDBM468959(1-[2-[4-[(3R,5S,6R)-5-Amino-6-(2,5-difluorophenyl)...)
Affinity DataIC50: 32.5nMAssay Description:Human DPP-4 ((39-766)-His) and mouse DPP-4 ((29-760)-His) are purified by gel chromatography for use in the assay. The final concentration of hDPP-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Eli Lilly

US Patent
LigandPNGBDBM468978(1-[1-[(3R,5S,6R)-5-Amino-6- (2,5- difluorophenyl)t...)
Affinity DataIC50: 33.4nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Mouse)
Eli Lilly

US Patent
LigandPNGBDBM468958(1-[2-[(3R,5S,6R)-5-Amino- 6-(2,5- difluorophenyl)t...)
Affinity DataIC50: 33.6nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Mouse)
Eli Lilly

US Patent
LigandPNGBDBM468964(1-[1-[(3R,5S,6R)-5-Amino-6-(2,5-difluorophenyl)tet...)
Affinity DataIC50: 36.8nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Mouse)
Eli Lilly

US Patent
LigandPNGBDBM468972((3S)-1-[2-[(3R,5S,6R)-5-Amino-6-(2,5-difluoropheny...)
Affinity DataIC50: 48nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Eli Lilly

US Patent
LigandPNGBDBM468957(1-[2-[(3R,5S,6R)-5-Amino-6-(2,5-difluorophenyl)tet...)
Affinity DataIC50: 48.3nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Eli Lilly

US Patent
LigandPNGBDBM468979(1-[1-[(3R,5S,6R)-5-Amino- 6-(2,5- difluorophenyl)t...)
Affinity DataIC50: 53.7nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Human)
Eli Lilly

US Patent
LigandPNGBDBM468976((3S)-1-[1-[(3R,5S,6R)-5-Amino-6-(2,5-difluoropheny...)
Affinity DataIC50: 56.2nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Mouse)
Eli Lilly

US Patent
LigandPNGBDBM468980(1-[1-[(3R,5S,6R)-5-Amino- 6-(2,5- difluorophenyl)t...)
Affinity DataIC50: 60.3nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

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