Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 9500
TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM471694(US10822342, Compound 2)
Affinity DataIC50: 23nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (αscreen) format (Perkin Elmer). All compounds tested were dissolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM471698(US10822342, Compound 6)
Affinity DataIC50: 37nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (αscreen) format (Perkin Elmer). All compounds tested were dissolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM471700(US10822342, Compound 8)
Affinity DataIC50: 38nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (αscreen) format (Perkin Elmer). All compounds tested were dissolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM471693(US10822342, Compound 1)
Affinity DataIC50: 46nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (αscreen) format (Perkin Elmer). All compounds tested were dissolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM471701(US10822342, Compound 9)
Affinity DataIC50: 52nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (αscreen) format (Perkin Elmer). All compounds tested were dissolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM471699(US10822342, Compound 7)
Affinity DataIC50: 60nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (αscreen) format (Perkin Elmer). All compounds tested were dissolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM471696(US10822342, Compound 4)
Affinity DataIC50: 65nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (αscreen) format (Perkin Elmer). All compounds tested were dissolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM471704(US10822342, Compound 12)
Affinity DataIC50: 84nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (αscreen) format (Perkin Elmer). All compounds tested were dissolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM471697(US10822342, Compound 5)
Affinity DataIC50: 112nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (αscreen) format (Perkin Elmer). All compounds tested were dissolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM471703(US10822342, Compound 11)
Affinity DataIC50: 143nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (αscreen) format (Perkin Elmer). All compounds tested were dissolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM471702(US10822342, Compound 10)
Affinity DataIC50: 186nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (αscreen) format (Perkin Elmer). All compounds tested were dissolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2021
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM471695(US10822342, Compound 3)
Affinity DataIC50: 992nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (αscreen) format (Perkin Elmer). All compounds tested were dissolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2021
Entry Details
US Patent