Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 9523
TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM472830(US10829500, Exam. 5)
Affinity DataIC50: 28nMAssay Description:It has been found that the compounds of the present invention are associated with inhibition of BACE1 activity. More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM472828(US10829500, Exam. 3)
Affinity DataIC50: 36nMAssay Description:It has been found that the compounds of the present invention are associated with inhibition of BACE1 activity. More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM472827(US10829500, Exam. 2)
Affinity DataIC50: 49nMAssay Description:It has been found that the compounds of the present invention are associated with inhibition of BACE1 activity. More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM472826(US10829500, Exam. 1)
Affinity DataIC50: 86nMAssay Description:It has been found that the compounds of the present invention are associated with inhibition of BACE1 activity. More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM472829(US10829500, Exam. 4)
Affinity DataIC50: 96nMAssay Description:It has been found that the compounds of the present invention are associated with inhibition of BACE1 activity. More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
Go to US Patent