Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 9610
TargetBeta-secretase 2(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476688(US10870635, Example 103 | (R)-3-Imino-2,2,5-trimet...)
Affinity DataIC50: 12nMAssay Description:A BACE2 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected compounds by AnaSpec BACE2 fluorescent as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476692(US10870635, Example 109 | (R)-5-(3-Fluoro-8-(prop-...)
Affinity DataIC50: 16nMAssay Description:A BACE2 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected compounds by AnaSpec BACE2 fluorescent as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476679(US10870635, Example 87 | (S)-6-(8-(3-Hydroxyprop-1...)
Affinity DataIC50: 17nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476666(US10870635, Example 72 | (S)-6-(3-Fluoro-8-(prop-1...)
Affinity DataIC50: 21nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476661(US10870635, Example 38 | (S)-6-(3-Chloro-5-(prop-1...)
Affinity DataIC50: 24nMAssay Description:A BACE2 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected compounds by AnaSpec BACE2 fluorescent as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476692(US10870635, Example 109 | (R)-5-(3-Fluoro-8-(prop-...)
Affinity DataIC50: 25nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476692(US10870635, Example 109 | (R)-5-(3-Fluoro-8-(prop-...)
Affinity DataIC50: 25nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476660(US10870635, Example 1 | (S)-2-Imino-3,6-dimethyl-6...)
Affinity DataIC50: 26nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476660(US10870635, Example 1 | (S)-2-Imino-3,6-dimethyl-6...)
Affinity DataIC50: 26nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476688(US10870635, Example 103 | (R)-3-Imino-2,2,5-trimet...)
Affinity DataIC50: 39nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476688(US10870635, Example 103 | (R)-3-Imino-2,2,5-trimet...)
Affinity DataIC50: 39nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476688(US10870635, Example 103 | (R)-3-Imino-2,2,5-trimet...)
Affinity DataIC50: 39nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476661(US10870635, Example 38 | (S)-6-(3-Chloro-5-(prop-1...)
Affinity DataIC50: 44nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476694((S)-6-(3-Chloro-8-(prop-1-yn-1-yl) dibenzo[b,d]thi...)
Affinity DataIC50: 44nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476673(US10870635, Example 80 | (6S)-2-Imino-3,6-dimethyl...)
Affinity DataIC50: 48nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476682(US10870635, Example 90 | (S)-6-(8-Cyclopropyldiben...)
Affinity DataIC50: 78nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476685(US10870635, Example 94 | (S)-2-Imino-3,6-dimethyl-...)
Affinity DataIC50: 81nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476670(US10870635, Example 79 | (S)-6-(5,5-Dioxido-8-(pro...)
Affinity DataIC50: 87nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476687(US10870635, Example 100 | (R)-5,5-Difluoro-4-methy...)
Affinity DataIC50: 202nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476678(US10870635, Example 86 | (S)-2-Imino-6-(8-(3-metho...)
Affinity DataIC50: 218nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476686(US10870635, Example 99 | (R)-6-Cyclopropyl-2-imino...)
Affinity DataIC50: 300nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476684(US10870635, Example 92 | (S)-6-(8-(Diethylamino)di...)
Affinity DataIC50: 300nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476683(US10870635, Example 91 | (S)-8-(2-Imino-1,4-dimeth...)
Affinity DataIC50: 300nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476681(US10870635, Example 89 | (S)-2-Imino-3,6-dimethyl-...)
Affinity DataIC50: 300nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476680(US10870635, Example 88 | (S)-6-(8-Bromodibenzo[b,d...)
Affinity DataIC50: 300nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476693(US10870635, Example 115 | (R)-3-Imino-1,5-dimethyl...)
Affinity DataIC50: 300nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476677(US10870635, Example 85 | (S)-8-(2-Imino-1,4-dimeth...)
Affinity DataIC50: 300nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476676(US10870635, Example 82 | (S)-6-(9,9-Difluoro-6-(pr...)
Affinity DataIC50: 300nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476691(US10870635, Example 106 | (S)-2-Imino-3-(2-methoxy...)
Affinity DataIC50: 300nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476675(US10870635, Example 81 | (S)-6-(9,9-Dimethyl-6-(pr...)
Affinity DataIC50: 300nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476690(US10870635, Example 105 | (S)-3-(2,2-Difluoroethyl...)
Affinity DataIC50: 300nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476689(US10870635, Example 104 | (R)-3-Imino-2,5-dimethyl...)
Affinity DataIC50: 300nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetCathepsin D(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476694((S)-6-(3-Chloro-8-(prop-1-yn-1-yl) dibenzo[b,d]thi...)
Affinity DataIC50: 3.90E+3nMAssay Description:Cathepsin D (Cat D) is a major intercellular member of the mammalian aspartic proteinase family and is thought to be in the normal degradation of int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetCathepsin D(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476692(US10870635, Example 109 | (R)-5-(3-Fluoro-8-(prop-...)
Affinity DataIC50: 1.08E+4nMAssay Description:Cathepsin D (Cat D) is a major intercellular member of the mammalian aspartic proteinase family and is thought to be in the normal degradation of int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetCathepsin D(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476660(US10870635, Example 1 | (S)-2-Imino-3,6-dimethyl-6...)
Affinity DataIC50: 1.23E+4nMAssay Description:Cathepsin D (Cat D) is a major intercellular member of the mammalian aspartic proteinase family and is thought to be in the normal degradation of int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent

TargetCathepsin D(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476688(US10870635, Example 103 | (R)-3-Imino-2,2,5-trimet...)
Affinity DataIC50: 1.72E+4nMAssay Description:Cathepsin D (Cat D) is a major intercellular member of the mammalian aspartic proteinase family and is thought to be in the normal degradation of int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent