Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 9631
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477080(US10888550, Compound 13 | N-(5-chloro-6-(2H-1,2,3-...)
Affinity DataIC50: 19nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477083(US10888550, Compound 16 | 4-(4-((5-chloro-6-(2H-1,...)
Affinity DataIC50: 25nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477077(US10888550, Compound 10 | N-(5-chloro-6-(4-methylo...)
Affinity DataIC50: 26nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477073(US10888550, Compound 6 | N-(5-chloro-6-(oxazol-2- ...)
Affinity DataIC50: 30nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477082(US10888550, Compound 15 | N-(5-chloro-6-(2H-1,2,3-...)
Affinity DataIC50: 33nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477090(US10888550, Compound 23 | (*S)-N-(5-chloro-6- (tet...)
Affinity DataIC50: 36nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477069(US10888550, Compound 2 | N-(5-chloro-6-(2H-1,2,3-t...)
Affinity DataIC50: 38nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477068(US10888550, Compound 1 | 5-(4-((5-chloro-6-(2H-1,2...)
Affinity DataIC50: 49nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477071(US10888550, Compound 4 | N-(6-(2H-1,2,3-triazol-2-...)
Affinity DataIC50: 50nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477076(US10888550, Compound 9 | N-(5-chloro-6-(5-methylox...)
Affinity DataIC50: 81nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477088(US10888550, Compound 21 | (*S)-N-(5-chloro-6- (tet...)
Affinity DataIC50: 87nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477078(US10888550, Compound 11 | 1-(7-cyanopyrazolo[1,5- ...)
Affinity DataIC50: 89nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477074(US10888550, Compound 7 | N-(5-chloro-6-(2H-1,2,3-t...)
Affinity DataIC50: 120nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477081(US10888550, Compound 14 | 1-(7-chloropyrazolo[1,5-...)
Affinity DataIC50: 209nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477079(US10888550, Compound 12 | 4-(5-(trifluoromethyl)-4...)
Affinity DataIC50: 219nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477091(US10888550, Compound 24 | (*R)-N-(5-chloro-6- (tet...)
Affinity DataIC50: 251nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477070(US10888550, Compound 3 | N-(5-chloro-6-(1H-pyrazol...)
Affinity DataIC50: 251nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477087(US10888550, Compound 20 | (*S)-N-(5-chloro-6- (tet...)
Affinity DataIC50: 355nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477072(US10888550, Compound 5 | 1-(8-fluoroimidazo[1,2-a]...)
Affinity DataIC50: 372nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477075(US10888550, Compound 8 | N-(5-chloro-6-(2H-1,2,3-t...)
Affinity DataIC50: 457nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477092(US10888550, Compound 25 | (*S)-N-(5-chloro-6-(1- m...)
Affinity DataIC50: 457nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477093(US10888550, Compound 26 | (*R)-N-(5-chloro-6-(1- m...)
Affinity DataIC50: 562nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477097(US10888550, Compound 30 | N-(6-((dimethyl(oxo)-lam...)
Affinity DataIC50: 830nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477089(US10888550, Compound 22 | (*R)-N-(5-chloro-6- (tet...)
Affinity DataIC50: 977nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477104(US10888550, Compound 33 | N-(5-chloro-6-((dimethyl...)
Affinity DataIC50: 980nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477094(US10888550, Compound 27 | (*S)-N-(5-chloro-6-(1- m...)
Affinity DataIC50: 1.02E+3nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477095(US10888550, Compound 28 | (*R)-N-(5-chloro-6-(1- m...)
Affinity DataIC50: 1.32E+3nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477085(US10888550, Compound 18 | (*R)-N-(5-chloro-6- (tet...)
Affinity DataIC50: 2.19E+3nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477084(US10888550, Compound 17 | (*S)-N-(5-chloro-6-(1- m...)
Affinity DataIC50: 2.34E+3nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477086(US10888550, Compound 19 | (*R)-N-(5-chloro-6-(1- m...)
Affinity DataIC50: 2.82E+3nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477101(US10888550, Compound 31 | 1-(8-fluoroimidazo[1,2-a...)
Affinity DataIC50: 3.16E+3nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477096(US10888550, Compound 29 | N-(6-((dimethyl(oxo)-lam...)
Affinity DataIC50: 6.00E+3nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477103(US10888550, Compound 32 | N-(6-((dimethyl(oxo)-lam...)
Affinity DataIC50: 8.13E+3nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent