Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with all data for entry = 9691
TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481930(US10913745, Example 8.07)
Affinity DataIC50: 1nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481899(US10913745, Example 1.13 | US10913745, Example 1.1...)
Affinity DataIC50: 1nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481899(US10913745, Example 1.13 | US10913745, Example 1.1...)
Affinity DataIC50: 1nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50187688(CHEMBL3828650 | US10913745, Example 1.11)
Affinity DataIC50: 1nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481932(US10913745, Example 8.09)
Affinity DataIC50: 1nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481920(US10913745, Example 7.01)
Affinity DataIC50: 1nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481931(US10913745, Example 8.08)
Affinity DataIC50: 1.5nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481896(US10913745, Example 1.10)
Affinity DataIC50: 2nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481911(US10913745, Example 1.25)
Affinity DataIC50: 2nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481929(US10913745, Example 8.06)
Affinity DataIC50: 3nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481921(US10913745, Example 7.02)
Affinity DataIC50: 3nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481891(US10913745, Example 1.05)
Affinity DataIC50: 4nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481909(US10913745, Example 1.23)
Affinity DataIC50: 4nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481905(US10913745, Example 1.19)
Affinity DataIC50: 4nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481933(US10913745, Example 9A | (−)-trans-3,5-Dichl...)
Affinity DataIC50: 4nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481922(US10913745, Example 7.03)
Affinity DataIC50: 4nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481934(US10913745, Example 9B | (−)-trans-3,5-Dichl...)
Affinity DataIC50: 5nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481926(US10913745, Example 8.03)
Affinity DataIC50: 5.5nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481908(US10913745, Example 1.22)
Affinity DataIC50: 7nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481889(US10913745, Example 1.03)
Affinity DataIC50: 7nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481924(US10913745, Example 8.01)
Affinity DataIC50: 7.5nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481890(US10913745, Example 1.04)
Affinity DataIC50: 8nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481923(US10913745, Example 8 | 4-{(3aR,6aR)-5-[3-(4-Trifl...)
Affinity DataIC50: 8.5nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481912(US10913745, Example 1.26)
Affinity DataIC50: 10nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481910(US10913745, Example 1.24)
Affinity DataIC50: 12nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481904(US10913745, Example 1.18)
Affinity DataIC50: 13nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481925(US10913745, Example 8.02)
Affinity DataIC50: 14nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481919(US10913745, Example 7 | (3aS,6aS)-5-(4-Sulfamoyl-b...)
Affinity DataIC50: 14.5nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481906(US10913745, Example 1.20)
Affinity DataIC50: 19nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481903(US10913745, Example 1.17)
Affinity DataIC50: 25nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481915(US10913745, Example 3 | (3aR,6aS)-3,5-Dichlorobenz...)
Affinity DataIC50: 31nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481901(US10913745, Example 1.15)
Affinity DataIC50: 58.5nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481900(US10913745, Example 1.14)
Affinity DataIC50: 64nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
Go to US Patent

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481928(US10913745, Example 8.05)
Affinity DataIC50: 93nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481907(US10913745, Example 1.21)
Affinity DataIC50: 118nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481895(US10913745, Example 1.09)
Affinity DataIC50: 118nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481927(US10913745, Example 8.04)
Affinity DataIC50: 166nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481892(US10913745, Example 1.06)
Affinity DataIC50: 255nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481887(US10913745, Example 1.01)
Affinity DataIC50: 293nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481913(US10913745, Example 2 | US10913745, Example 2.01 |...)
Affinity DataIC50: 342nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481898(US10913745, Example 1.12)
Affinity DataIC50: 440nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481888(US10913745, Example 1.02)
Affinity DataIC50: 444nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481916(US10913745, Example 4 | (3aR,6aS)-3,5-Dichlorobenz...)
Affinity DataIC50: 573nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481918(US10913745, Example 6 | (3aR,6aS)-3,5-Dichlorobenz...)
Affinity DataIC50: 622nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481886(US10913745, Example 1 | (3aR,6aS)-3,5-Dichlorobenz...)
Affinity DataIC50: 1.16E+3nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481894(US10913745, Example 1.08)
Affinity DataIC50: 1.20E+3nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481917(US10913745, Example 5 | 4-((3aR,6aS)-5-((3,5-Dichl...)
Affinity DataIC50: 1.34E+3nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481913(US10913745, Example 2 | US10913745, Example 2.01 |...)
Affinity DataIC50: 1.50E+3nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481893(US10913745, Example 1.07)
Affinity DataIC50: 6.11E+3nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
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Date in BDB:
8/30/2021
Entry Details
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