Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 9741
TargetTyrosine-protein kinase Lck(Human)
Oxular Acquisitions

US Patent
LigandPNGBDBM255476(US9499486, 1 | US10125100, Example 1 | US9751837, ...)
Affinity DataKd:  4.20nMAssay Description:c-Src and Syk: The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
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TargetMitogen-activated protein kinase 14(Human)
Oxular Acquisitions

US Patent
LigandPNGBDBM255476(US9499486, 1 | US10125100, Example 1 | US9751837, ...)
Affinity DataKd:  2.80nMAssay Description:p38 MAPKα Method 1: The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen) are evaluated indirectly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase SYK(Human)
Oxular Acquisitions

US Patent
LigandPNGBDBM255476(US9499486, 1 | US10125100, Example 1 | US9751837, ...)
Affinity DataKd:  7.10nMAssay Description:c-Src and Syk: The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Lck(Human)
Oxular Acquisitions

US Patent
LigandPNGBDBM298375(US10125100, Example 2 | 4-((4-((4-(3-(5-(tert-Buty...)
Affinity DataKd:  5.80nMAssay Description:c-Src and Syk: The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 14(Human)
Oxular Acquisitions

US Patent
LigandPNGBDBM298375(US10125100, Example 2 | 4-((4-((4-(3-(5-(tert-Buty...)
Affinity DataKd:  23nMAssay Description:p38 MAPKα Method 1: The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen) are evaluated indirectly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase SYK(Human)
Oxular Acquisitions

US Patent
LigandPNGBDBM298375(US10125100, Example 2 | 4-((4-((4-(3-(5-(tert-Buty...)
Affinity DataKd:  18nMAssay Description:c-Src and Syk: The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Lck(Human)
Oxular Acquisitions

US Patent
LigandPNGBDBM298446(US10125100, Example 44 | (4-((4-((4-(3-(5-(tert-Bu...)
Affinity DataKd:  5.30nMAssay Description:c-Src and Syk: The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 14(Human)
Oxular Acquisitions

US Patent
LigandPNGBDBM298446(US10125100, Example 44 | (4-((4-((4-(3-(5-(tert-Bu...)
Affinity DataKd:  1.90nMAssay Description:p38 MAPKα Method 1: The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen) are evaluated indirectly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase SYK(Human)
Oxular Acquisitions

US Patent
LigandPNGBDBM298446(US10125100, Example 44 | (4-((4-((4-(3-(5-(tert-Bu...)
Affinity DataKd:  6.60nMAssay Description:c-Src and Syk: The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent