Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 10112
TargetIndoleamine 2,3-dioxygenase 1(Human)
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

US Patent
LigandPNGBDBM514233(US11053207, Compound 6A | The Preparation of (+-)(...)
Affinity DataIC50: 11nMAssay Description:Firstly, the compound was subject to a 3-fold gradient dilution. 1 μL of each concentration was added to a 96-well plate; 50 μL of the IDO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

US Patent
LigandPNGBDBM514211((+-(Z) N-(3-bromo-4-fluorophenyl-N'-hydroxy-4-((2-...)
Affinity DataIC50: 22nMAssay Description:Firstly, the compound was subject to a 3-fold gradient dilution. 1 μL of each concentration was added to a 96-well plate; 50 μL of the IDO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

US Patent
LigandPNGBDBM514244(The Preparation of (+-) (Z)-N-(3-bromo-4-fluorophe...)
Affinity DataIC50: 35nMAssay Description:Firstly, the compound was subject to a 3-fold gradient dilution. 1 μL of each concentration was added to a 96-well plate; 50 μL of the IDO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

US Patent
LigandPNGBDBM514246(The Preparation of (+-) (Z)-N-(3-bromo-4-fluorophe...)
Affinity DataIC50: 55nMAssay Description:Firstly, the compound was subject to a 3-fold gradient dilution. 1 μL of each concentration was added to a 96-well plate; 50 μL of the IDO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

US Patent
LigandPNGBDBM514215(The Preparation of (+-)(Z)-N-(3-bromo-4-fluorophen...)
Affinity DataIC50: 74nMAssay Description:Firstly, the compound was subject to a 3-fold gradient dilution. 1 μL of each concentration was added to a 96-well plate; 50 μL of the IDO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

US Patent
LigandPNGBDBM514233(US11053207, Compound 6A | The Preparation of (+-)(...)
Affinity DataIC50: 82nMAssay Description:Firstly, the compound was subject to a 3-fold gradient dilution. 1 μL of each concentration was added to a 96-well plate; 50 μL of the IDO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

US Patent
LigandPNGBDBM514233(US11053207, Compound 6A | The Preparation of (+-)(...)
Affinity DataIC50: 88nMAssay Description:Firstly, the compound was subject to a 3-fold gradient dilution. 1 μL of each concentration was added to a 96-well plate; 50 μL of the IDO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

US Patent
LigandPNGBDBM514251(The Preparation of (+-)(Z)-N-(3-Br-4-fluorophenyl)...)
Affinity DataIC50: 120nMAssay Description:Firstly, the compound was subject to a 3-fold gradient dilution. 1 μL of each concentration was added to a 96-well plate; 50 μL of the IDO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

US Patent
LigandPNGBDBM514250(The Preparation of (+-) (Z)-N-(3-bromo-4-fluorophe...)
Affinity DataIC50: 180nMAssay Description:Firstly, the compound was subject to a 3-fold gradient dilution. 1 μL of each concentration was added to a 96-well plate; 50 μL of the IDO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

US Patent
LigandPNGBDBM514252(The Preparation of (+-)(Z)-N-(3-bromo-4-fluorophen...)
Affinity DataIC50: 360nMAssay Description:Firstly, the compound was subject to a 3-fold gradient dilution. 1 μL of each concentration was added to a 96-well plate; 50 μL of the IDO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

US Patent
LigandPNGBDBM514238(The Preparation of (+-) (Z)-N-(3-bromo-4-fluorophe...)
Affinity DataIC50: 2.60E+3nMAssay Description:Firstly, the compound was subject to a 3-fold gradient dilution. 1 μL of each concentration was added to a 96-well plate; 50 μL of the IDO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

US Patent
LigandPNGBDBM514214(US11053207, Compound 2)
Affinity DataIC50: 3.00E+3nMAssay Description:Firstly, the compound was subject to a 3-fold gradient dilution. 1 μL of each concentration was added to a 96-well plate; 50 μL of the IDO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

US Patent
LigandPNGBDBM514232(The Preparation of (+-)(Z)-N′-hydroxy-4-((4-...)
Affinity DataIC50: 3.60E+3nMAssay Description:Firstly, the compound was subject to a 3-fold gradient dilution. 1 μL of each concentration was added to a 96-well plate; 50 μL of the IDO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

US Patent
LigandPNGBDBM514245(US11053207, Compound 10)
Affinity DataIC50: 5.00E+3nMAssay Description:Firstly, the compound was subject to a 3-fold gradient dilution. 1 μL of each concentration was added to a 96-well plate; 50 μL of the IDO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

US Patent
LigandPNGBDBM514213(US11053207, Compound 1B)
Affinity DataIC50: 5.20E+3nMAssay Description:Firstly, the compound was subject to a 3-fold gradient dilution. 1 μL of each concentration was added to a 96-well plate; 50 μL of the IDO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

US Patent
LigandPNGBDBM514212(US11053207, Compound 1A)
Affinity DataIC50: 5.60E+3nMAssay Description:Firstly, the compound was subject to a 3-fold gradient dilution. 1 μL of each concentration was added to a 96-well plate; 50 μL of the IDO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

US Patent
LigandPNGBDBM514241(The Preparation of (+-)(Z)-N-(3-pentafluoride thio...)
Affinity DataIC50: 1.40E+4nMAssay Description:Firstly, the compound was subject to a 3-fold gradient dilution. 1 μL of each concentration was added to a 96-well plate; 50 μL of the IDO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

US Patent
LigandPNGBDBM514247(The Preparation of (+-)(Z)-N-(3-chloro-4-fluorophe...)
Affinity DataIC50: 1.80E+4nMAssay Description:Firstly, the compound was subject to a 3-fold gradient dilution. 1 μL of each concentration was added to a 96-well plate; 50 μL of the IDO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

US Patent
LigandPNGBDBM514216(The Preparation of (+-)(Z)-N-(4-fluoro-3-(trifluor...)
Affinity DataIC50: 1.90E+4nMAssay Description:Firstly, the compound was subject to a 3-fold gradient dilution. 1 μL of each concentration was added to a 96-well plate; 50 μL of the IDO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50126142(4-Phenylimidazole | CHEMBL14145 | US11053207, Comp...)
Affinity DataIC50: 3.90E+4nMAssay Description:Firstly, the compound was subject to a 3-fold gradient dilution. 1 μL of each concentration was added to a 96-well plate; 50 μL of the IDO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
US Patent