Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 9985
TargetSRSF protein kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50500359(CHEMBL3747611 | US11066363, Compound 13)
Affinity DataIC50: 0.884nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2021
Entry Details
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TargetSRSF protein kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50500360(CHEMBL3747134 | US11066363, Compound 9)
Affinity DataIC50: 1.15nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2021
Entry Details
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TargetSRSF protein kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50500357(CHEMBL3746522 | US11066363, Compound 31)
Affinity DataIC50: 1.91nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2021
Entry Details
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TargetSRSF protein kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM504520(9-ethyl-6,6-dimethyl-11-oxo-8- (pyrimidin-5-yl)-6,...)
Affinity DataIC50: 2.53nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2021
Entry Details
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TargetSRSF protein kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM504519((9-ethyl-6,6-dimethyl-11-oxo-8- (pyridin-4-yl)-6,1...)
Affinity DataIC50: 2.61nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2021
Entry Details
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TargetSRSF protein kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50500351(CHEMBL3746960 | US11066363, Compound 19)
Affinity DataIC50: 2.66nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2021
Entry Details
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TargetSRSF protein kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50500356(CHEMBL3747406 | US11066363, Compound 7)
Affinity DataIC50: 3.01nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2021
Entry Details
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TargetSRSF protein kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50500355(CHEMBL3747108 | US11066363, Compound 36)
Affinity DataIC50: 4.75nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2021
Entry Details
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TargetSRSF protein kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50500353(CHEMBL3746395 | US11066363, Compound 10)
Affinity DataIC50: 5.09nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2021
Entry Details
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TargetSRSF protein kinase 2(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50500357(CHEMBL3746522 | US11066363, Compound 31)
Affinity DataIC50: 6.60nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2021
Entry Details
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TargetSRSF protein kinase 2(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50500359(CHEMBL3747611 | US11066363, Compound 13)
Affinity DataIC50: 7.46nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2021
Entry Details
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TargetSRSF protein kinase 2(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50500351(CHEMBL3746960 | US11066363, Compound 19)
Affinity DataIC50: 8.57nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2021
Entry Details
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TargetSRSF protein kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50362781(CHEMBL1738797 | US9126931, 366 | Alectinib | 12565...)
Affinity DataIC50: 11nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2021
Entry Details
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TargetSRSF protein kinase 2(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50500356(CHEMBL3747406 | US11066363, Compound 7)
Affinity DataIC50: 12.4nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2021
Entry Details
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TargetSRSF protein kinase 2(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM504520(9-ethyl-6,6-dimethyl-11-oxo-8- (pyrimidin-5-yl)-6,...)
Affinity DataIC50: 12.5nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2021
Entry Details
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TargetSRSF protein kinase 2(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM504519((9-ethyl-6,6-dimethyl-11-oxo-8- (pyridin-4-yl)-6,1...)
Affinity DataIC50: 13.2nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2021
Entry Details
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TargetSRSF protein kinase 2(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50500353(CHEMBL3746395 | US11066363, Compound 10)
Affinity DataIC50: 14.5nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2021
Entry Details
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TargetSRSF protein kinase 2(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50500355(CHEMBL3747108 | US11066363, Compound 36)
Affinity DataIC50: 23.6nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2021
Entry Details
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TargetSRSF protein kinase 2(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50362781(CHEMBL1738797 | US9126931, 366 | Alectinib | 12565...)
Affinity DataIC50: 28.2nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2021
Entry Details
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TargetSRSF protein kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50512854(CHEMBL4468747 | US11066363, Compound 37)
Affinity DataIC50: 35.6nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2021
Entry Details
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TargetSRSF protein kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM504532(4-(3-cyano-9-ethyl-6,6-dimethyl-11- oxo-6,11-dihyd...)
Affinity DataIC50: 41nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2021
Entry Details
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TargetSRSF protein kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50500352(CHEMBL3746665 | US11066363, Compound 17)
Affinity DataIC50: 103nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2021
Entry Details
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