Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 10183
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

US Patent
LigandPNGBDBM518688(US11253514, Compound 1 | US11116764, Compound 1 | ...)
Affinity DataKi:  2.04nMAssay Description:Table 2: Incubation conditions: Reactions were carried out in 50 mM Tris-HCl (pH 7.4) containing 10 mM MgCl2, 0.5 mM EDTA for 60 minutes at 37° C. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

US Patent
LigandPNGBDBM518702(US11253514, Compound 3 | US11116764, Compound 3 | ...)
Affinity DataKi:  3.67nMAssay Description:Table 2: Incubation conditions: Reactions were carried out in 50 mM Tris-HCl (pH 7.4) containing 10 mM MgCl2, 0.5 mM EDTA for 60 minutes at 37° C. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

US Patent
LigandPNGBDBM518701(US11253514, Compound 2 | US11116764, Compound 2 | ...)
Affinity DataKi:  4.96nMAssay Description:Table 2: Incubation conditions: Reactions were carried out in 50 mM Tris-HCl (pH 7.4) containing 10 mM MgCl2, 0.5 mM EDTA for 60 minutes at 37° C. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Suven Life Sciences

US Patent
LigandPNGBDBM518702(US11253514, Compound 3 | US11116764, Compound 3 | ...)
Affinity DataKi:  926nMAssay Description:Table 3: Incubation conditions: Reactions were carried out in 67 mM Tris-HCl (pH 7.4) for 4 hours at 37° C. The reaction was terminated by rapid vacu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Suven Life Sciences

US Patent
LigandPNGBDBM518688(US11253514, Compound 1 | US11116764, Compound 1 | ...)
Affinity DataKi:  2.51E+3nMAssay Description:Table 3: Incubation conditions: Reactions were carried out in 67 mM Tris-HCl (pH 7.4) for 4 hours at 37° C. The reaction was terminated by rapid vacu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Suven Life Sciences

US Patent
LigandPNGBDBM518701(US11253514, Compound 2 | US11116764, Compound 2 | ...)
Affinity DataKi: >1.00E+4nMAssay Description:Table 3: Incubation conditions: Reactions were carried out in 67 mM Tris-HCl (pH 7.4) for 4 hours at 37° C. The reaction was terminated by rapid vacu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent