Compile Data Set for Download or QSAR
Report error Found 76 Enz. Inhib. hit(s) with all data for entry = 10157
TargetRap guanine nucleotide exchange factor 4(Human)
University Of Texas

US Patent
LigandPNGBDBM517717(ZL0524 | US11124489, Entry 32)
Affinity DataIC50: 1.20E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 4(Human)
University Of Texas

US Patent
LigandPNGBDBM517689(NY0562 | US11124489, Compound 33)
Affinity DataIC50: 1.90E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 4(Human)
University Of Texas

US Patent
LigandPNGBDBM517666(NY0617 | US11124489, Compound 10)
Affinity DataIC50: 2.20E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 4(Human)
University Of Texas

US Patent
LigandPNGBDBM517684(NY0725 | US11124489, Compound 26)
Affinity DataIC50: 2.20E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 4(Human)
University Of Texas

US Patent
LigandPNGBDBM517687(NY0495 | US11124489, Compound 31)
Affinity DataIC50: 2.20E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 4(Human)
University Of Texas

US Patent
LigandPNGBDBM517688(NY0561 | US11124489, Compound 32)
Affinity DataIC50: 2.20E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 4(Human)
University Of Texas

US Patent
LigandPNGBDBM517670(NY0460 | US11124489, Compound 14)
Affinity DataIC50: 2.30E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 4(Human)
University Of Texas

US Patent
LigandPNGBDBM517685(NY0726 | US11124489, Compound 27)
Affinity DataIC50: 2.30E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517670(NY0460 | US11124489, Compound 14)
Affinity DataIC50: 2.40E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 4(Human)
University Of Texas

US Patent
LigandPNGBDBM517696(ZL0475 | US11124489, Entry 11)
Affinity DataIC50: 2.50E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 4(Human)
University Of Texas

US Patent
LigandPNGBDBM517718(ZL0682 | US11124489, Entry 33)
Affinity DataIC50: 2.50E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517689(NY0562 | US11124489, Compound 33)
Affinity DataIC50: 2.70E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 4(Human)
University Of Texas

US Patent
LigandPNGBDBM517706(ZL0562 | US11124489, Entry 19)
Affinity DataIC50: 3.00E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517688(NY0561 | US11124489, Compound 32)
Affinity DataIC50: 3.00E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 4(Human)
University Of Texas

US Patent
LigandPNGBDBM517667(US11124489, Compound 15 | NY0618 | US11124489, Com...)
Affinity DataIC50: 3.30E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 4(Human)
University Of Texas

US Patent
LigandPNGBDBM517698(ZL0477 | US11124489, Entry 13)
Affinity DataIC50: 3.40E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517684(NY0725 | US11124489, Compound 26)
Affinity DataIC50: 3.60E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517717(ZL0524 | US11124489, Entry 32)
Affinity DataIC50: 3.60E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517685(NY0726 | US11124489, Compound 27)
Affinity DataIC50: 4.20E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 4(Human)
University Of Texas

US Patent
LigandPNGBDBM517662(ESI-09 | US11124489, Compound 1)
Affinity DataIC50: 4.40E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 4(Human)
University Of Texas

US Patent
LigandPNGBDBM517694(ESI-09 | US11124489, Entry 5)
Affinity DataIC50: 4.40E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 4(Human)
University Of Texas

US Patent
LigandPNGBDBM517681(NY0654 | US11124489, Compound 23)
Affinity DataIC50: 4.50E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517687(NY0495 | US11124489, Compound 31)
Affinity DataIC50: 4.60E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517675(NY0541 | US11124489, Compound 17b)
Affinity DataIC50: 5.10E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517696(ZL0475 | US11124489, Entry 11)
Affinity DataIC50: 5.40E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 4(Human)
University Of Texas

US Patent
LigandPNGBDBM517704(ZL0560 | US11124489, Entry 17)
Affinity DataIC50: 5.40E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517701(ZL0479 | US11124489, Entry 15)
Affinity DataIC50: 5.50E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517681(NY0654 | US11124489, Compound 23)
Affinity DataIC50: 5.60E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517682(NY0655 | US11124489, Compound 24)
Affinity DataIC50: 5.60E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517704(ZL0560 | US11124489, Entry 17)
Affinity DataIC50: 5.60E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517702(ZL0559 | US11124489, Entry 16)
Affinity DataIC50: 6.10E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 4(Human)
University Of Texas

US Patent
LigandPNGBDBM517701(ZL0479 | US11124489, Entry 15)
Affinity DataIC50: 6.30E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517698(ZL0477 | US11124489, Entry 13)
Affinity DataIC50: 6.40E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517692(NY0563 | US11124489, Compound 36)
Affinity DataIC50: 6.70E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 4(Human)
University Of Texas

US Patent
LigandPNGBDBM517682(NY0655 | US11124489, Compound 24)
Affinity DataIC50: 7.00E+3nMAssay Description:From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517667(US11124489, Compound 15 | NY0618 | US11124489, Com...)
Affinity DataIC50: 7.20E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517666(NY0617 | US11124489, Compound 10)
Affinity DataIC50: 7.30E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517678(NY0642 | US11124489, Compound 20)
Affinity DataIC50: 7.80E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517691(NY0564 | US11124489, Compound 35)
Affinity DataIC50: 8.50E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517663(NY0613 | US11124489, Compound 7)
Affinity DataIC50: 8.60E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517665(NY0616 | US11124489, Compound 9)
Affinity DataIC50: 9.00E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517669(NY0402 | US11124489, Compound 13)
Affinity DataIC50: 9.50E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517683(NY0724 | US11124489, Compound 25)
Affinity DataIC50: 9.90E+3nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517676(NY0542 | US11124489, Compound 18)
Affinity DataIC50: 1.02E+4nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517664(NY0615 | US11124489, Compound 8)
Affinity DataIC50: 1.02E+4nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517662(ESI-09 | US11124489, Compound 1)
Affinity DataIC50: 1.08E+4nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517694(ESI-09 | US11124489, Entry 5)
Affinity DataIC50: 1.08E+4nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517718(ZL0682 | US11124489, Entry 33)
Affinity DataIC50: 1.13E+4nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517679(NY0643 | US11124489, Compound 21)
Affinity DataIC50: 1.14E+4nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetRap guanine nucleotide exchange factor 3(Human)
University Of Texas

US Patent
LigandPNGBDBM517680(NY0653 | US11124489, Compound 22)
Affinity DataIC50: 1.14E+4nMAssay Description:To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

Displayed 1 to 50 (of 76 total ) | Next | Last >>
Jump to: