Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 10203
TargetTyrosine-protein kinase SYK(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520087(US11142535, Compound 1R)
Affinity DataIC50: 10nMAssay Description:Measure of SYK protein kinase activity was carried out by using the Caliper mobility shift assay. The compound was dissolved with DMSO and diluted wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520104(US11142535, Compound 21)
Affinity DataIC50: 10nMAssay Description:Measure of SYK protein kinase activity was carried out by using the Caliper mobility shift assay. The compound was dissolved with DMSO and diluted wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520088(US11142535, Compound 2R)
Affinity DataIC50: 10nMAssay Description:Measure of SYK protein kinase activity was carried out by using the Caliper mobility shift assay. The compound was dissolved with DMSO and diluted wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520090(US11142535, Compound 4R)
Affinity DataIC50: 10nMAssay Description:Measure of SYK protein kinase activity was carried out by using the Caliper mobility shift assay. The compound was dissolved with DMSO and diluted wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520091(US11142535, Compound 5R)
Affinity DataIC50: 10nMAssay Description:Measure of SYK protein kinase activity was carried out by using the Caliper mobility shift assay. The compound was dissolved with DMSO and diluted wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520092(US11142535, Compound 6)
Affinity DataIC50: 10nMAssay Description:Measure of SYK protein kinase activity was carried out by using the Caliper mobility shift assay. The compound was dissolved with DMSO and diluted wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520093(US11142535, Compound 7)
Affinity DataIC50: 10nMAssay Description:Measure of SYK protein kinase activity was carried out by using the Caliper mobility shift assay. The compound was dissolved with DMSO and diluted wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520094(US11142535, Compound 8R)
Affinity DataIC50: 10nMAssay Description:Measure of SYK protein kinase activity was carried out by using the Caliper mobility shift assay. The compound was dissolved with DMSO and diluted wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520099(US11142535, Compound 14)
Affinity DataIC50: 20nMAssay Description:HDAC activity was measured by the Synergy MX Multi-Function Microplate Reader. The compounds were dissolved with DMSO, and transferred to a 384 well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520103(US11142535, Compound 20)
Affinity DataIC50: 20nMAssay Description:HDAC activity was measured by the Synergy MX Multi-Function Microplate Reader. The compounds were dissolved with DMSO, and transferred to a 384 well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520106(US11142535, Compound 23)
Affinity DataIC50: 30nMAssay Description:HDAC activity was measured by the Synergy MX Multi-Function Microplate Reader. The compounds were dissolved with DMSO, and transferred to a 384 well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520093(US11142535, Compound 7)
Affinity DataIC50: 30nMAssay Description:HDAC activity was measured by the Synergy MX Multi-Function Microplate Reader. The compounds were dissolved with DMSO, and transferred to a 384 well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520093(US11142535, Compound 7)
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520100(US11142535, Compound 17)
Affinity DataIC50: 50nMAssay Description:HDAC activity was measured by the Synergy MX Multi-Function Microplate Reader. The compounds were dissolved with DMSO, and transferred to a 384 well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520103(US11142535, Compound 20)
Affinity DataIC50: 50nMAssay Description:Measure of SYK protein kinase activity was carried out by using the Caliper mobility shift assay. The compound was dissolved with DMSO and diluted wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520105(US11142535, Compound 22)
Affinity DataIC50: 50nMAssay Description:Measure of SYK protein kinase activity was carried out by using the Caliper mobility shift assay. The compound was dissolved with DMSO and diluted wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520106(US11142535, Compound 23)
Affinity DataIC50: 50nMAssay Description:Measure of SYK protein kinase activity was carried out by using the Caliper mobility shift assay. The compound was dissolved with DMSO and diluted wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520092(US11142535, Compound 6)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520097(US11142535, Compound 12)
Affinity DataIC50: 100nMAssay Description:Measure of SYK protein kinase activity was carried out by using the Caliper mobility shift assay. The compound was dissolved with DMSO and diluted wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520098(US11142535, Compound 13)
Affinity DataIC50: 100nMAssay Description:Measure of SYK protein kinase activity was carried out by using the Caliper mobility shift assay. The compound was dissolved with DMSO and diluted wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520101(US11142535, Compound 18)
Affinity DataIC50: 100nMAssay Description:HDAC activity was measured by the Synergy MX Multi-Function Microplate Reader. The compounds were dissolved with DMSO, and transferred to a 384 well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520104(US11142535, Compound 21)
Affinity DataIC50: 100nMAssay Description:HDAC activity was measured by the Synergy MX Multi-Function Microplate Reader. The compounds were dissolved with DMSO, and transferred to a 384 well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520095(US11142535, Compound 9R)
Affinity DataIC50: 100nMAssay Description:Measure of SYK protein kinase activity was carried out by using the Caliper mobility shift assay. The compound was dissolved with DMSO and diluted wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520097(US11142535, Compound 12)
Affinity DataIC50: 200nMAssay Description:HDAC activity was measured by the Synergy MX Multi-Function Microplate Reader. The compounds were dissolved with DMSO, and transferred to a 384 well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520098(US11142535, Compound 13)
Affinity DataIC50: 200nMAssay Description:HDAC activity was measured by the Synergy MX Multi-Function Microplate Reader. The compounds were dissolved with DMSO, and transferred to a 384 well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520096(US11142535, Compound 11)
Affinity DataIC50: 500nMAssay Description:Measure of SYK protein kinase activity was carried out by using the Caliper mobility shift assay. The compound was dissolved with DMSO and diluted wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520099(US11142535, Compound 14)
Affinity DataIC50: 500nMAssay Description:Measure of SYK protein kinase activity was carried out by using the Caliper mobility shift assay. The compound was dissolved with DMSO and diluted wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520102(US11142535, Compound 19)
Affinity DataIC50: 500nMAssay Description:HDAC activity was measured by the Synergy MX Multi-Function Microplate Reader. The compounds were dissolved with DMSO, and transferred to a 384 well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520101(US11142535, Compound 18)
Affinity DataIC50: 500nMAssay Description:Measure of SYK protein kinase activity was carried out by using the Caliper mobility shift assay. The compound was dissolved with DMSO and diluted wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520105(US11142535, Compound 22)
Affinity DataIC50: 500nMAssay Description:HDAC activity was measured by the Synergy MX Multi-Function Microplate Reader. The compounds were dissolved with DMSO, and transferred to a 384 well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520089(US11142535, Compound 3R)
Affinity DataIC50: 500nMAssay Description:Measure of SYK protein kinase activity was carried out by using the Caliper mobility shift assay. The compound was dissolved with DMSO and diluted wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520100(US11142535, Compound 17)
Affinity DataIC50: 1.00E+3nMAssay Description:Measure of SYK protein kinase activity was carried out by using the Caliper mobility shift assay. The compound was dissolved with DMSO and diluted wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520102(US11142535, Compound 19)
Affinity DataIC50: 1.00E+3nMAssay Description:Measure of SYK protein kinase activity was carried out by using the Caliper mobility shift assay. The compound was dissolved with DMSO and diluted wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520092(US11142535, Compound 6)
Affinity DataIC50: 1.00E+3nMAssay Description:HDAC activity was measured by the Synergy MX Multi-Function Microplate Reader. The compounds were dissolved with DMSO, and transferred to a 384 well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520107(US11142535, Compound 10)
Affinity DataIC50: 2.00E+3nMAssay Description:HDAC activity was measured by the Synergy MX Multi-Function Microplate Reader. The compounds were dissolved with DMSO, and transferred to a 384 well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent