Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 10214
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM520619(US11147801, Compound 8 | 2-methyl-6-(2'-methyl-[1,...)
Affinity DataIC50: 100nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM520620(US11147801, Compound 12 | 5-(4-(2,5-dimethyl-1H-py...)
Affinity DataIC50: 100nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM520621(US11147801, Compound 19 | 1-methyl-5-(2,3,5,6-tetr...)
Affinity DataIC50: 100nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM520622(US11147801, Compound 24 | 2-methyl-6-(2,3,5,6-tetr...)
Affinity DataIC50: 100nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM520617(US11147801, Compound 1 | 1-methyl-5-(2'-methyl-[1,...)
Affinity DataIC50: 100nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM520618(US11147801, Compound 2 | 1-methyl-5-(2'-methyl-[1,...)
Affinity DataIC50: 100nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM520623(US11147801, Compound 3 | 5-([1,1'-biphenyl]-4-yl)-...)
Affinity DataIC50: 550nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM520624(US11147801, Compound 4 | 6-([1,1'-biphenyl]-4-yl)-...)
Affinity DataIC50: 550nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM520625(US11147801, Compound 11 | 2-methyl-6-(2'-methyl-[1...)
Affinity DataIC50: 550nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM520626(US11147801, Compound 13 | 6-(4-(2,5-dimethyl-1H-py...)
Affinity DataIC50: 550nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM520627(US11147801, Compound 25 | 1-methyl-5-(2'-(morpholi...)
Affinity DataIC50: 550nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM520628(US11147801, Compound 29 | 1-methyl-5-(2'-((4-methy...)
Affinity DataIC50: 550nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM520629(US11147801, Compound 33 | 1-methyl-5-(2,3,5,6-tetr...)
Affinity DataIC50: 550nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM520630(US11147801, Compound 34 | 1-methyl-5-(2,3,5,6-tetr...)
Affinity DataIC50: 550nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM520631(US11147801, Compound 36 | 1-methyl-5-(2,3,5,6-tetr...)
Affinity DataIC50: 550nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM520632(US11147801, Compound 38 | 2-methyl-6-(2,3,5,6-tetr...)
Affinity DataIC50: 550nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM520633(US11147801, Compound 39 | 2-methyl-6-(2,3,5,6-tetr...)
Affinity DataIC50: 550nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM520634(US11147801, Compound 40 | 5-(3'-((dimethylamino)me...)
Affinity DataIC50: 550nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM520635(US11147801, Compound 15 | 1-methyl-5-(3'-(morpholi...)
Affinity DataIC50: 1.00E+3nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM520636(US11147801, Compound 16 | 2-methyl-6-(3'-(morpholi...)
Affinity DataIC50: 1.00E+3nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM520637(US11147801, Compound 17 | 1-methyl-5-(3'-(pyrrolid...)
Affinity DataIC50: 1.00E+3nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM520638(US11147801, Compound 20 | 1-methyl-6-(3'-(piperidi...)
Affinity DataIC50: 1.00E+3nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM520639(US11147801, Compound 26 | 2-methyl-6-(2'-(morpholi...)
Affinity DataIC50: 1.00E+3nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM520640(US11147801, Compound 27 | 1-methyl-5-(2'-(pyrrolid...)
Affinity DataIC50: 1.00E+3nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM520641(US11147801, Compound 30 | 2-methyl-6-(2'-((4-methy...)
Affinity DataIC50: 1.00E+3nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM520642(US11147801, Compound 31 | 1-methyl-5-(4'-(morpholi...)
Affinity DataIC50: 1.00E+3nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM520643(US11147801, Compound 32 | 5-(3'-acetamido-[1,1'-bi...)
Affinity DataIC50: 1.00E+3nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM520644(US11147801, Compound 35 | 1-methyl-5-(2,3,5,6-tetr...)
Affinity DataIC50: 1.00E+3nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM520645(US11147801, Compound 37 | 1-methyl-5-(2,3,5,6-tetr...)
Affinity DataIC50: 1.00E+3nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent