Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 10356
TargetGlycogen synthase kinase-3 beta(Human)
The Broad Institute

US Patent
LigandPNGBDBM50325983(6-(2-(4-(2,4-dichlorophenyl)-5-(4-methyl-1H-imidaz...)
Affinity DataIC50: 2nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetGlycogen synthase kinase-3 alpha(Human)
The Broad Institute

US Patent
LigandPNGBDBM50325983(6-(2-(4-(2,4-dichlorophenyl)-5-(4-methyl-1H-imidaz...)
Affinity DataIC50: 2nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
The Broad Institute

US Patent
LigandPNGBDBM530233(US11203601, Compound Table 1.5)
Affinity DataIC50: 14nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
The Broad Institute

US Patent
LigandPNGBDBM530241(US11203601, Compound Table 1.13)
Affinity DataIC50: 24nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
The Broad Institute

US Patent
LigandPNGBDBM303229(US10137122, Compound 108 | US11203601, Compound Ta...)
Affinity DataIC50: 42nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
The Broad Institute

US Patent
LigandPNGBDBM530233(US11203601, Compound Table 1.5)
Affinity DataIC50: 65nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
The Broad Institute

US Patent
LigandPNGBDBM50508889(CHEMBL4438334 | US11203601, Compound Table 1.18)
Affinity DataIC50: 66nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetGlycogen synthase kinase-3 alpha(Human)
The Broad Institute

US Patent
LigandPNGBDBM530239(US11203601, Compound Table 1.11)
Affinity DataIC50: 69nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
The Broad Institute

US Patent
LigandPNGBDBM530241(US11203601, Compound Table 1.13)
Affinity DataIC50: 110nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
The Broad Institute

US Patent
LigandPNGBDBM530243(US11203601, Compound Table 1.15)
Affinity DataIC50: 155nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
The Broad Institute

US Patent
LigandPNGBDBM530231(US11203601, Compound Table 1.3)
Affinity DataIC50: 203nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
The Broad Institute

US Patent
LigandPNGBDBM303229(US10137122, Compound 108 | US11203601, Compound Ta...)
Affinity DataIC50: 225nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
The Broad Institute

US Patent
LigandPNGBDBM530229(US11203601, Compound Table 1.1)
Affinity DataIC50: 238nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
The Broad Institute

US Patent
LigandPNGBDBM530239(US11203601, Compound Table 1.11)
Affinity DataIC50: 245nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
The Broad Institute

US Patent
LigandPNGBDBM530237(US11203601, Compound Table 1.9)
Affinity DataIC50: 293nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
The Broad Institute

US Patent
LigandPNGBDBM530229(US11203601, Compound Table 1.1)
Affinity DataIC50: 384nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
The Broad Institute

US Patent
LigandPNGBDBM530243(US11203601, Compound Table 1.15)
Affinity DataIC50: 447nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
The Broad Institute

US Patent
LigandPNGBDBM530231(US11203601, Compound Table 1.3)
Affinity DataIC50: 455nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
The Broad Institute

US Patent
LigandPNGBDBM50508889(CHEMBL4438334 | US11203601, Compound Table 1.18)
Affinity DataIC50: 507nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetGlycogen synthase kinase-3 alpha(Human)
The Broad Institute

US Patent
LigandPNGBDBM530235(US11203601, Compound Table 1.7)
Affinity DataIC50: 599nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
The Broad Institute

US Patent
LigandPNGBDBM530237(US11203601, Compound Table 1.9)
Affinity DataIC50: 1.18E+3nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
The Broad Institute

US Patent
LigandPNGBDBM530244(US11203601, Compound Table 1.16)
Affinity DataIC50: 1.89E+3nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
The Broad Institute

US Patent
LigandPNGBDBM530235(US11203601, Compound Table 1.7)
Affinity DataIC50: 2.27E+3nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
The Broad Institute

US Patent
LigandPNGBDBM530244(US11203601, Compound Table 1.16)
Affinity DataIC50: 3.66E+3nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
The Broad Institute

US Patent
LigandPNGBDBM530240(US11203601, Compound Table 1.12)
Affinity DataIC50: 4.36E+3nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
The Broad Institute

US Patent
LigandPNGBDBM530232(US11203601, Compound Table 1.4)
Affinity DataIC50: 6.23E+3nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
The Broad Institute

US Patent
LigandPNGBDBM530242(US11203601, Compound Table 1.14)
Affinity DataIC50: 1.05E+4nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
The Broad Institute

US Patent
LigandPNGBDBM530242(US11203601, Compound Table 1.14)
Affinity DataIC50: 1.06E+4nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
The Broad Institute

US Patent
LigandPNGBDBM530240(US11203601, Compound Table 1.12)
Affinity DataIC50: 1.17E+4nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
The Broad Institute

US Patent
LigandPNGBDBM530232(US11203601, Compound Table 1.4)
Affinity DataIC50: 1.25E+4nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
The Broad Institute

US Patent
LigandPNGBDBM530230(US11203601, Compound Table 1.2)
Affinity DataIC50: 1.85E+4nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
The Broad Institute

US Patent
LigandPNGBDBM530230(US11203601, Compound Table 1.2)
Affinity DataIC50: 2.86E+4nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
The Broad Institute

US Patent
LigandPNGBDBM530236(US11203601, Compound Table 1.8)
Affinity DataIC50: 3.00E+4nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
The Broad Institute

US Patent
LigandPNGBDBM530236(US11203601, Compound Table 1.8)
Affinity DataIC50: 3.00E+4nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
The Broad Institute

US Patent
LigandPNGBDBM530238(US11203601, Compound Table 1.10)
Affinity DataIC50: 3.00E+4nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
The Broad Institute

US Patent
LigandPNGBDBM530238(US11203601, Compound Table 1.10)
Affinity DataIC50: 3.00E+4nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
The Broad Institute

US Patent
LigandPNGBDBM530234(US11203601, Compound Table 1.6)
Affinity DataIC50: 3.00E+4nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
The Broad Institute

US Patent
LigandPNGBDBM530234(US11203601, Compound Table 1.6)
Affinity DataIC50: 3.00E+4nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent