Compile Data Set for Download or QSAR
Report error Found 284 Enz. Inhib. hit(s) with all data for entry = 10410
TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM50271435(CHEMBL4126815 | US11225469, Compound 292)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533635(US11225469, Compound 135)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM50271398(CHEMBL4126631 | US11225469, Compound 297)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM50271414(CHEMBL4128834 | US11225469, Compound 296)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533776(US11225469, Compound 299)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533846(US11225469, Compound 243 | US11225469, Compound 24...)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM50271462(CHEMBL2132783 | US11225469, Compound 28)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM50271428(CHEMBL4128967 | US11225469, Compound 298)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533845(US11225469, Compound 242 | US11225469, Compound 23...)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533563(US11225469, Compound 36)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533847(US11225469, Compound 244 | US11225469, Compound 24...)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533853(US11225469, Compound 247)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533640(US11225469, Compound 141)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533688(US11225469, Compound 188)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533690(US11225469, Compound 190)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533832(US11225469, Compound 228)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533622(US11225469, Compound 117)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533693(US11225469, Compound 193)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533835(US11225469, Compound 230)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533695(US11225469, Compound 195)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM50271400(CHEMBL4130080 | US11225469, Compound 291)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533626(US11225469, Compound 122)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM50271405(CHEMBL4125915 | US11225469, Compound 262)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM50271415(CHEMBL4125786 | US11225469, Compound 264)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM50271419(CHEMBL4128252 | US11225469, Compound 263)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM50271420(CHEMBL4129623 | US11225469, Compound 266)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM50271404(CHEMBL4127244 | US11225469, Compound 265)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533744(US11225469, Compound 269)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533673(US11225469, Compound 175)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533743(US11225469, Compound 267 | N-(4,6-dimethylpyridin-...)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533602(US11225469, Compound 100)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533677(US11225469, Compound 179)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM50271427(CHEMBL4127154 | US11225469, Compound 275)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM50271458(CHEMBL3559789 | US11225469, Compound 30)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM50271417(CHEMBL4127018 | US11225469, Compound 250)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM50271523(CHEMBL4129229 | US11225469, Compound 252)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM50271522(CHEMBL4126002 | US11225469, Compound 251)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533730(US11225469, Compound 254)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM195605(NCT-502 | US11225469, Compound 72)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533731(US11225469, Compound 255)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM50271418(CHEMBL4128391 | US11225469, Compound 258)
Affinity DataIC50: 5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM50271430(CHEMBL4127077 | US11225469, Compound 295)
Affinity DataIC50: 7.50E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533633(US11225469, Compound 134)
Affinity DataIC50: 7.50E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533777(US11225469, Compound 300)
Affinity DataIC50: 7.50E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533641(US11225469, Compound 142)
Affinity DataIC50: 7.50E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533779(US11225469, Compound 302)
Affinity DataIC50: 7.50E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533785(US11225469, Compound 22)
Affinity DataIC50: 7.50E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533617(US11225469, Compound 110)
Affinity DataIC50: 7.50E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533618(US11225469, Compound 111)
Affinity DataIC50: 7.50E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM50271506(CHEMBL2135778 | US11225469, Compound 116)
Affinity DataIC50: 7.50E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

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