Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 10479
TargetAdenosine receptor A2a(Human)
Nuvation Bio

US Patent
LigandPNGBDBM539111(US11254670, Compound 1)
Affinity DataIC50: 2.60nMAssay Description:A second A2A adenosine receptor radioligand binding assay protocol was used. The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2022
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Nuvation Bio

US Patent
LigandPNGBDBM539137(US11254670, Compound 7)
Affinity DataIC50: 3.5nMAssay Description:A second A2A adenosine receptor radioligand binding assay protocol was used. The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2022
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Nuvation Bio

US Patent
LigandPNGBDBM539140(US11254670, Compound 77)
Affinity DataIC50: 5.40nMAssay Description:A second A2A adenosine receptor radioligand binding assay protocol was used. The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2022
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Nuvation Bio

US Patent
LigandPNGBDBM539144(US11254670, Compound 79)
Affinity DataIC50: 9.5nMAssay Description:A second A2A adenosine receptor radioligand binding assay protocol was used. The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2022
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Nuvation Bio

US Patent
LigandPNGBDBM539145(US11254670, Compound 80)
Affinity DataIC50: 17nMAssay Description:A second A2A adenosine receptor radioligand binding assay protocol was used. The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2022
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Nuvation Bio

US Patent
LigandPNGBDBM539142(US11254670, Compound 78)
Affinity DataIC50: 49nMAssay Description:A second A2A adenosine receptor radioligand binding assay protocol was used. The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2022
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Nuvation Bio

US Patent
LigandPNGBDBM539136(US11254670, Compound 6)
Affinity DataIC50: 113nMAssay Description:A second A2A adenosine receptor radioligand binding assay protocol was used. The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2022
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Nuvation Bio

US Patent
LigandPNGBDBM539138(US11254670, Compound 55)
Affinity DataIC50: 179nMAssay Description:A second A2A adenosine receptor radioligand binding assay protocol was used. The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2022
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Nuvation Bio

US Patent
LigandPNGBDBM539129(US11254670, Compound 3)
Affinity DataIC50: 2.60E+3nMAssay Description:A second A2A adenosine receptor radioligand binding assay protocol was used. The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2022
Entry Details
US Patent