Compile Data Set for Download or QSAR
Report error Found 86 Enz. Inhib. hit(s) with all data for entry = 10519
LigandPNGBDBM543871(US11279712, Example 15 | US11279712, Example 48 | ...)
Affinity DataIC50: 0.0500nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543919(US11279712, Example 52 | (1s,3′r,6′r,7...)
Affinity DataIC50: 0.107nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2022
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LigandPNGBDBM543869((1s,3′r,6′s,7′s,11′s,12...)
Affinity DataIC50: 0.123nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
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LigandPNGBDBM543875((1s,3′r,6′r,7′r,11's,12′r)...)
Affinity DataIC50: 0.126nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2022
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LigandPNGBDBM543889((1S,3'R,6'S,7'S,11'S,12'R)- 7'-((4-acetyl-1- piper...)
Affinity DataIC50: 0.172nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543870(US11279712, Example 7 | (1S,3'R,6'S,7'S,11'S,12'R)...)
Affinity DataIC50: 0.181nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2022
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LigandPNGBDBM543890((1s,3′r,6′r,7′s,11′s,12...)
Affinity DataIC50: 0.182nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2022
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LigandPNGBDBM543871(US11279712, Example 15 | US11279712, Example 48 | ...)
Affinity DataIC50: 0.185nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543871(US11279712, Example 15 | US11279712, Example 48 | ...)
Affinity DataIC50: 0.212nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2022
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LigandPNGBDBM543918((1S,3'R,6'S,7'S,11'S)- 6-chloro-7'- (hydroxymethyl...)
Affinity DataIC50: 0.222nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543891((1s,3′r,6′r,7′s,8′e,11R...)
Affinity DataIC50: 0.224nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543868((1s,3′r,6's,7's,11's,12′r)-6-chloro-11...)
Affinity DataIC50: 0.225nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543896(US11279712, Example 59 | (1S,3'R,6'R,7'S,11'S,12'R...)
Affinity DataIC50: 0.226nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
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LigandPNGBDBM543878((1S,3'R,6'R,7'S,11'S,12'R)- 6-chloro-N-(2- methoxy...)
Affinity DataIC50: 0.237nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2022
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LigandPNGBDBM543876((1S,3'R,6'R,7'S,11'S,12'R)- 7'-(1- azetidinylcarbo...)
Affinity DataIC50: 0.246nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543871(US11279712, Example 15 | US11279712, Example 48 | ...)
Affinity DataIC50: 0.252nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543870(US11279712, Example 7 | (1S,3'R,6'S,7'S,11'S,12'R)...)
Affinity DataIC50: 0.257nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543881(US11279712, Example 31 | (1S,3'R,6'S,7'S,11'S,12'R...)
Affinity DataIC50: 0.261nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543903((1S,3'R,6'S,7'R,11'S,12'R)- 6-chloro-7'-((4-(2- me...)
Affinity DataIC50: 0.265nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543910((1S,3'R,6'R,7'S,10'S,11'S)- 6-chloro-7'- (hydroxym...)
Affinity DataIC50: 0.268nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543928(US11279712, Example 61 | (1s,3′r,6′r,7...)
Affinity DataIC50: 0.281nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543908((1s,3′r,6′r,7′s,11′s,12...)
Affinity DataIC50: 0.284nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543895(2- ((1S,3'R,6'S,7'S,11'S,12'R)- 6-chloro-11',12'- ...)
Affinity DataIC50: 0.287nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543904((1S,3'R,6'R,7'S,8'E, 11'S,12'R)- 6-chloro-7'-((9aS...)
Affinity DataIC50: 0.288nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543881(US11279712, Example 31 | (1S,3'R,6'S,7'S,11'S,12'R...)
Affinity DataIC50: 0.291nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543877((1S,3'R,6'S,7'S,11'S,12'R)- 6-chloro-7'-((9aS)- he...)
Affinity DataIC50: 0.291nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543883(US11279712, Example 16 | (1S,3'R,6'S,7'S,11'S,12'R...)
Affinity DataIC50: 0.317nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543871(US11279712, Example 15 | US11279712, Example 48 | ...)
Affinity DataIC50: 0.329nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543893((1s,3′r,6′r,7′s,8′e,11R...)
Affinity DataIC50: 0.336nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543912((1s,3′r,6′r,7′r,11′s,12...)
Affinity DataIC50: 0.338nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543873((1s,3′r,6's,7's,11's,12′r)-6-chloro-11...)
Affinity DataIC50: 0.353nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543936(US11279712, Example 85 | (1S,3'R,6'R,7'S,12'R)- 6-...)
Affinity DataIC50: 0.359nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543889((1S,3'R,6'S,7'S,11'S,12'R)- 7'-((4-acetyl-1- piper...)
Affinity DataIC50: 0.375nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543916((1s,3′r,6′r,7′r,8′e,11R...)
Affinity DataIC50: 0.377nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543929(US11279712, Example 62 | (1S,3'R,6'R,7'R,8'E, 11'S...)
Affinity DataIC50: 0.388nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543909((1S,3'R,6'S,7'R,11'S,12'R)- 6-chloro-7'-((4-(2- me...)
Affinity DataIC50: 0.408nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543941(US11279712, Example 77 | (1s,36′r,6′r,...)
Affinity DataIC50: 0.442nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543888((1s,3′r,6′r,7′s, 1s, 12′r)...)
Affinity DataIC50: 0.489nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543877((1S,3'R,6'S,7'S,11'S,12'R)- 6-chloro-7'-((9aS)- he...)
Affinity DataIC50: 0.493nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543911((1s,3′r,6′r,7′s,11′s,12...)
Affinity DataIC50: 0.502nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543887(US11279712, Example 30 | (1S,3'R,6'S,7'S,11'S,12'R...)
Affinity DataIC50: 0.516nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543905((1S,3'R,6'R,7'S,11'S,12'R)- 6-chloro-7'-((3,3- dif...)
Affinity DataIC50: 0.517nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543923(US11279712, Example 56 | (1s,3′r,6's,7′...)
Affinity DataIC50: 0.520nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543886((1s,3′r,6′s,7′r,11′s,12...)
Affinity DataIC50: 0.532nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543879((1S,3'R,6'S,7'S,11'S,12'R)- 6-chloro-7'-((4-(2- me...)
Affinity DataIC50: 0.542nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543927(US11279712, Example 60 | (1s,3′r,6′r,7...)
Affinity DataIC50: 0.552nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543934((1S,3'R,6'R,7'S,11'S,12'R)- 6-chloro-7'-((S)- hydr...)
Affinity DataIC50: 0.552nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543872((1S,3'R,6'S,7'S,11'S,12'R)- 6-chloro-11',12'- dime...)
Affinity DataIC50: 0.602nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543924(US11279712, Example 57 | (1S,3'R,6'R,7'R,11'S,12'R...)
Affinity DataIC50: 0.604nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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LigandPNGBDBM543872((1S,3'R,6'S,7'S,11'S,12'R)- 6-chloro-11',12'- dime...)
Affinity DataIC50: 0.622nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
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