Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 10863
TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575479(US11459337, Compound WX059)
Affinity DataIC50: 1.10nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575460(US11459337, Compound WX038)
Affinity DataIC50: 1.30nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575450(US11459337, Compound WX028)
Affinity DataIC50: 1.60nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575473(US11459337, Compound WX052)
Affinity DataIC50: 1.80nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575448(US11459337, Compound WX026)
Affinity DataIC50: 2nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575478(US11459337, Compound WX058)
Affinity DataIC50: 2.10nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575453(US11459337, Compound WX031)
Affinity DataIC50: 2.40nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575435(US11459337, Compound WX003)
Affinity DataIC50: 2.90nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575449(US11459337, Compound WX027)
Affinity DataIC50: 3.30nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575451(US11459337, Compound WX029)
Affinity DataIC50: 3.80nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575477(US11459337, Compound WX057)
Affinity DataIC50: 5nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575458(US11459337, Compound WX036)
Affinity DataIC50: 5.5nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575438(US11459337, Compound WX007)
Affinity DataIC50: 5.70nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575433(US11459337, Compound WX001)
Affinity DataIC50: 6.80nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575480(US11459337, Compound WX060)
Affinity DataIC50: 7.30nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575452(US11459337, Compound WX030)
Affinity DataIC50: 7.5nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575461(US11459337, Compound WX039)
Affinity DataIC50: 7.90nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575436(US11459337, Compound WX005)
Affinity DataIC50: 8.70nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575459(US11459337, Compound WX037)
Affinity DataIC50: 9.20nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575437(US11459337, Compound WX006)
Affinity DataIC50: 9.90nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575457(US11459337, Compound WX035)
Affinity DataIC50: 10.7nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575470(US11459337, Compound WX049)
Affinity DataIC50: 11.2nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575475(US11459337, Compound WX055)
Affinity DataIC50: 11.7nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575464(US11459337, Compound WX043)
Affinity DataIC50: 12.2nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575455(US11459337, Compound WX033)
Affinity DataIC50: 12.8nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575456(US11459337, Compound WX034)
Affinity DataIC50: 12.8nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575471(US11459337, Compound WX050)
Affinity DataIC50: 13.4nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575446(US11459337, Compound WX024)
Affinity DataIC50: 13.5nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575472(US11459337, Compound WX051)
Affinity DataIC50: 13.7nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575454(US11459337, Compound WX032)
Affinity DataIC50: 15.2nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575476(US11459337, Compound WX056)
Affinity DataIC50: 17nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575445(US11459337, Compound WX015)
Affinity DataIC50: 20.5nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575440(US11459337, Compound WX009)
Affinity DataIC50: 21.3nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575463(US11459337, Compound WX041)
Affinity DataIC50: 21.4nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575447(US11459337, Compound WX025)
Affinity DataIC50: 23.6nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575439(US11459337, Compound WX008)
Affinity DataIC50: 27.2nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575468(US11459337, Compound WX047)
Affinity DataIC50: 29.6nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575462(US11459337, Compound WX040)
Affinity DataIC50: 30nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575444(US11459337, Compound WX014)
Affinity DataIC50: 30.3nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575465(US11459337, Compound WX044)
Affinity DataIC50: 40.7nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575441(US11459337, Compound WX010)
Affinity DataIC50: 45.9nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575443(US11459337, Compound WX013)
Affinity DataIC50: 60.1nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575434(US11459337, Compound WX002)
Affinity DataIC50: 89.5nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575467(US11459337, Compound WX046)
Affinity DataIC50: 231nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575466(US11459337, Compound WX045)
Affinity DataIC50: 278nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575442(US11459337, Compound WX011)
Affinity DataIC50: 357nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575474(US11459337, Compound WX054)
Affinity DataIC50: 363nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575469(US11459337, Compound WX048)
Affinity DataIC50: 460nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent