Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 10965
TargetCytochrome P450 2D6(Human)
Artax Biopharma

US Patent
LigandPNGBDBM581355(US11505526, Compound V-4)
Affinity DataIC50: 5.00E+3nMAssay Description:The effect of compounds IV-6, IV-7, and V-4 on Cytochromes P450 (CYP) inhibition was evaluated. For each isozyme, microsomes-buffer-substrate mixture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
Go to US Patent

TargetCytochrome P450 2C19(Human)
Artax Biopharma

US Patent
LigandPNGBDBM581350(US11505526, Compound IV-6)
Affinity DataIC50: 5.00E+3nMAssay Description:The effect of compounds IV-6, IV-7, and V-4 on Cytochromes P450 (CYP) inhibition was evaluated. For each isozyme, microsomes-buffer-substrate mixture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Artax Biopharma

US Patent
LigandPNGBDBM581350(US11505526, Compound IV-6)
Affinity DataIC50: 5.00E+3nMAssay Description:The effect of compounds IV-6, IV-7, and V-4 on Cytochromes P450 (CYP) inhibition was evaluated. For each isozyme, microsomes-buffer-substrate mixture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Artax Biopharma

US Patent
LigandPNGBDBM581350(US11505526, Compound IV-6)
Affinity DataIC50: 5.00E+3nMAssay Description:The effect of compounds IV-6, IV-7, and V-4 on Cytochromes P450 (CYP) inhibition was evaluated. For each isozyme, microsomes-buffer-substrate mixture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
Go to US Patent

TargetCytochrome P450 2C19(Human)
Artax Biopharma

US Patent
LigandPNGBDBM581355(US11505526, Compound V-4)
Affinity DataIC50: 5.00E+3nMAssay Description:The effect of compounds IV-6, IV-7, and V-4 on Cytochromes P450 (CYP) inhibition was evaluated. For each isozyme, microsomes-buffer-substrate mixture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
Go to US Patent

TargetCytochrome P450 1A2(Human)
Artax Biopharma

US Patent
LigandPNGBDBM581355(US11505526, Compound V-4)
Affinity DataIC50: 5.00E+3nMAssay Description:The effect of compounds IV-6, IV-7, and V-4 on Cytochromes P450 (CYP) inhibition was evaluated. For each isozyme, microsomes-buffer-substrate mixture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
Go to US Patent

TargetCytochrome P450 2C9(Human)
Artax Biopharma

US Patent
LigandPNGBDBM581350(US11505526, Compound IV-6)
Affinity DataIC50: 1.25E+4nMAssay Description:The effect of compounds IV-6, IV-7, and V-4 on Cytochromes P450 (CYP) inhibition was evaluated. For each isozyme, microsomes-buffer-substrate mixture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
Go to US Patent

TargetCytochrome P450 2C9(Human)
Artax Biopharma

US Patent
LigandPNGBDBM581355(US11505526, Compound V-4)
Affinity DataIC50: 1.25E+4nMAssay Description:The effect of compounds IV-6, IV-7, and V-4 on Cytochromes P450 (CYP) inhibition was evaluated. For each isozyme, microsomes-buffer-substrate mixture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Artax Biopharma

US Patent
LigandPNGBDBM581351(US11505526, Compound IV-7)
Affinity DataIC50: 1.25E+4nMAssay Description:The effect of compounds IV-6, IV-7, and V-4 on Cytochromes P450 (CYP) inhibition was evaluated. For each isozyme, microsomes-buffer-substrate mixture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Artax Biopharma

US Patent
LigandPNGBDBM581350(US11505526, Compound IV-6)
Affinity DataIC50: 1.25E+4nMAssay Description:The effect of compounds IV-6, IV-7, and V-4 on Cytochromes P450 (CYP) inhibition was evaluated. For each isozyme, microsomes-buffer-substrate mixture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
Go to US Patent

TargetCytochrome P450 1A2(Human)
Artax Biopharma

US Patent
LigandPNGBDBM581350(US11505526, Compound IV-6)
Affinity DataIC50: 3.50E+4nMAssay Description:The effect of compounds IV-6, IV-7, and V-4 on Cytochromes P450 (CYP) inhibition was evaluated. For each isozyme, microsomes-buffer-substrate mixture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Artax Biopharma

US Patent
LigandPNGBDBM581355(US11505526, Compound V-4)
Affinity DataIC50: 3.50E+4nMAssay Description:The effect of compounds IV-6, IV-7, and V-4 on Cytochromes P450 (CYP) inhibition was evaluated. For each isozyme, microsomes-buffer-substrate mixture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
Go to US Patent

TargetCytochrome P450 2C19(Human)
Artax Biopharma

US Patent
LigandPNGBDBM581351(US11505526, Compound IV-7)
Affinity DataIC50: 5.00E+4nMAssay Description:The effect of compounds IV-6, IV-7, and V-4 on Cytochromes P450 (CYP) inhibition was evaluated. For each isozyme, microsomes-buffer-substrate mixture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Artax Biopharma

US Patent
LigandPNGBDBM581351(US11505526, Compound IV-7)
Affinity DataIC50: 5.00E+4nMAssay Description:The effect of compounds IV-6, IV-7, and V-4 on Cytochromes P450 (CYP) inhibition was evaluated. For each isozyme, microsomes-buffer-substrate mixture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Artax Biopharma

US Patent
LigandPNGBDBM581351(US11505526, Compound IV-7)
Affinity DataIC50: 5.00E+4nMAssay Description:The effect of compounds IV-6, IV-7, and V-4 on Cytochromes P450 (CYP) inhibition was evaluated. For each isozyme, microsomes-buffer-substrate mixture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
Go to US Patent

TargetCytochrome P450 2C9(Human)
Artax Biopharma

US Patent
LigandPNGBDBM581351(US11505526, Compound IV-7)
Affinity DataIC50: 5.00E+4nMAssay Description:The effect of compounds IV-6, IV-7, and V-4 on Cytochromes P450 (CYP) inhibition was evaluated. For each isozyme, microsomes-buffer-substrate mixture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
Go to US Patent

TargetCytochrome P450 1A2(Human)
Artax Biopharma

US Patent
LigandPNGBDBM581351(US11505526, Compound IV-7)
Affinity DataIC50: 5.00E+4nMAssay Description:The effect of compounds IV-6, IV-7, and V-4 on Cytochromes P450 (CYP) inhibition was evaluated. For each isozyme, microsomes-buffer-substrate mixture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Artax Biopharma

US Patent
LigandPNGBDBM581355(US11505526, Compound V-4)
Affinity DataIC50: 5.00E+4nMAssay Description:The effect of compounds IV-6, IV-7, and V-4 on Cytochromes P450 (CYP) inhibition was evaluated. For each isozyme, microsomes-buffer-substrate mixture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
Go to US Patent