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Found
34
Enz. Inhib. hit(s) with all data for entry = 11020
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM50541818
(CHEMBL4648907 | US11530219, Compound 16)
Copy SMILES
Copy InChI
Affinity Data
Ki: 130nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM50541817
(CHEMBL4635421 | US11530219, Compound 14)
Copy SMILES
Copy InChI
Affinity Data
Ki: 440nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM50541818
(CHEMBL4648907 | US11530219, Compound 16)
Copy SMILES
Copy InChI
Affinity Data
IC50: 517nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM50541819
(CHEMBL4645406 | US11530219, Compound 17)
Copy SMILES
Copy InChI
Affinity Data
Ki: 970nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM65454
(Lenalidomide | US9694015, 6.1 | 191732-72-6 | Revl...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.49E+3nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM50541817
(CHEMBL4635421 | US11530219, Compound 14)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.60E+3nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM585777
(US11530219, Compound 4)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.40E+3nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM50541819
(CHEMBL4645406 | US11530219, Compound 17)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.44E+3nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM585784
(US11530219, Compound 12)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.90E+3nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM585783
(US11530219, Compound 11)
Copy SMILES
Copy InChI
Affinity Data
Ki: 4.20E+3nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM585787
(US11530219, Compound 15)
Copy SMILES
Copy InChI
Affinity Data
Ki: 4.30E+3nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM65454
(Lenalidomide | US9694015, 6.1 | 191732-72-6 | Revl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.19E+3nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM585782
(US11530219, Compound 10)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5.40E+3nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM585781
(US11530219, Compound 9)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.30E+3nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM585779
(US11530219, Compound 6)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.50E+3nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM585785
(US11530219, Compound 13)
Copy SMILES
Copy InChI
Affinity Data
Ki: 8.30E+3nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM585774
(US11530219, Compound 1)
Copy SMILES
Copy InChI
Affinity Data
Ki: 8.50E+3nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM585777
(US11530219, Compound 4)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.50E+3nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM585780
(US11530219, Compound 7)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.11E+4nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM585778
(US11530219, Compound 5)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.22E+4nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM585776
(US11530219, Compound 3)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.25E+4nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM585775
(US11530219, Compound 2)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.36E+4nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM585776
(US11530219, Compound 3)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.36E+4nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM585784
(US11530219, Compound 12)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.38E+4nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM585783
(US11530219, Compound 11)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.47E+4nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM585787
(US11530219, Compound 15)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.52E+4nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM585782
(US11530219, Compound 10)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.89E+4nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM585781
(US11530219, Compound 9)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.21E+4nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM585779
(US11530219, Compound 6)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.29E+4nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM585785
(US11530219, Compound 13)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.89E+4nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM585774
(US11530219, Compound 1)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.97E+4nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM585780
(US11530219, Compound 7)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.89E+4nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM585778
(US11530219, Compound 5)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.25E+4nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM585775
(US11530219, Compound 2)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.75E+4nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/17/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL