Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 11150
TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
Bugworks Research

US Patent
LigandPNGBDBM595416(US11590142, Compound 7)
Affinity DataIC50: 18nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
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TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
Bugworks Research

US Patent
LigandPNGBDBM595412(US11590142, Compound 2)
Affinity DataIC50: 27nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
Go to US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
Bugworks Research

US Patent
LigandPNGBDBM595415(US11590142, Compound 5)
Affinity DataIC50: 32nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
Go to US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
Bugworks Research

US Patent
LigandPNGBDBM595413(US11590142, Compound 3)
Affinity DataIC50: 47nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
Go to US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
Bugworks Research

US Patent
LigandPNGBDBM595414(US11590142, Compound 4)
Affinity DataIC50: 51nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
Go to US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
Bugworks Research

US Patent
LigandPNGBDBM595411(US11590142, Compound 1)
Affinity DataIC50: 67nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bugworks Research

US Patent
LigandPNGBDBM50462032(CHEMBL560739 | CHEBI:3720 | US11590142, Compound C...)
Affinity DataIC50: 150nMAssay Description:Compounds were solubilised to 100 mM in DMSO before dilution in HBPS to 300 μM. 6-Point concentration-response curves were generated using 3.16-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
Go to US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
Bugworks Research

US Patent
LigandPNGBDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 233nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bugworks Research

US Patent
LigandPNGBDBM595414(US11590142, Compound 4)
Affinity DataIC50: 3.80E+4nMAssay Description:Compounds were solubilised to 100 mM in DMSO before dilution in HBPS to 300 μM. 6-Point concentration-response curves were generated using 3.16-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bugworks Research

US Patent
LigandPNGBDBM595413(US11590142, Compound 3)
Affinity DataIC50: 4.00E+4nMAssay Description:Compounds were solubilised to 100 mM in DMSO before dilution in HBPS to 300 μM. 6-Point concentration-response curves were generated using 3.16-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bugworks Research

US Patent
LigandPNGBDBM595423(US11590142, Compound 13)
Affinity DataIC50: 5.80E+4nMAssay Description:Compounds were solubilised to 100 mM in DMSO before dilution in HBPS to 300 μM. 6-Point concentration-response curves were generated using 3.16-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bugworks Research

US Patent
LigandPNGBDBM595418(US11590142, Compound 6)
Affinity DataIC50: 6.00E+4nMAssay Description:Compounds were solubilised to 100 mM in DMSO before dilution in HBPS to 300 μM. 6-Point concentration-response curves were generated using 3.16-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bugworks Research

US Patent
LigandPNGBDBM595415(US11590142, Compound 5)
Affinity DataIC50: 8.20E+4nMAssay Description:Compounds were solubilised to 100 mM in DMSO before dilution in HBPS to 300 μM. 6-Point concentration-response curves were generated using 3.16-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bugworks Research

US Patent
LigandPNGBDBM595421(US11590142, Compound 10 | US11590142, Compound 12)
Affinity DataIC50: 9.80E+4nMAssay Description:Compounds were solubilised to 100 mM in DMSO before dilution in HBPS to 300 μM. 6-Point concentration-response curves were generated using 3.16-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bugworks Research

US Patent
LigandPNGBDBM595420(US11590142, Compound 9)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds were solubilised to 100 mM in DMSO before dilution in HBPS to 300 μM. 6-Point concentration-response curves were generated using 3.16-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bugworks Research

US Patent
LigandPNGBDBM595429(US11590142, Compound 14)
Affinity DataIC50: 1.50E+5nMAssay Description:Compounds were solubilised to 100 mM in DMSO before dilution in HBPS to 300 μM. 6-Point concentration-response curves were generated using 3.16-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bugworks Research

US Patent
LigandPNGBDBM595416(US11590142, Compound 7)
Affinity DataIC50: 3.00E+5nMAssay Description:Compounds were solubilised to 100 mM in DMSO before dilution in HBPS to 300 μM. 6-Point concentration-response curves were generated using 3.16-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bugworks Research

US Patent
LigandPNGBDBM595419(US11590142, Compound 8)
Affinity DataIC50: 3.00E+5nMAssay Description:Compounds were solubilised to 100 mM in DMSO before dilution in HBPS to 300 μM. 6-Point concentration-response curves were generated using 3.16-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bugworks Research

US Patent
LigandPNGBDBM595421(US11590142, Compound 10 | US11590142, Compound 12)
Affinity DataIC50: 3.00E+5nMAssay Description:Compounds were solubilised to 100 mM in DMSO before dilution in HBPS to 300 μM. 6-Point concentration-response curves were generated using 3.16-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
Go to US Patent