Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 11250
TargetSerine/threonine-protein kinase mTOR(Human)
Medicinal Bioconvergence Research Center

US Patent
LigandPNGBDBM602735(US11649231, Example 1-13 | (5Z)-5-[[1-(3-chlorophe...)
Affinity DataIC50: 0nMAssay Description:Among the compounds of the Examples 1-1 to 1-61, compounds that showed excellent inhibitory activity (inhibitory activity of 85% or more at 20 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
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TargetSerine/threonine-protein kinase mTOR(Human)
Medicinal Bioconvergence Research Center

US Patent
LigandPNGBDBM602730((5Z)-5-[(1-phenylpyrazole-4-yl)methylene]-2-thioxo...)
Affinity DataIC50: 24nMAssay Description:Among the compounds of the Examples 1-1 to 1-61, compounds that showed excellent inhibitory activity (inhibitory activity of 85% or more at 20 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
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TargetSerine/threonine-protein kinase mTOR(Human)
Medicinal Bioconvergence Research Center

US Patent
LigandPNGBDBM602730((5Z)-5-[(1-phenylpyrazole-4-yl)methylene]-2-thioxo...)
Affinity DataIC50: 45nMAssay Description:Among the compounds of the Examples 1-1 to 1-61, compounds that showed excellent inhibitory activity (inhibitory activity of 85% or more at 20 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
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TargetSerine/threonine-protein kinase mTOR(Human)
Medicinal Bioconvergence Research Center

US Patent
LigandPNGBDBM602736(US11649231, Example 1-17 | (5Z)-5-[[1-(4-chlorophe...)
Affinity DataIC50: 69nMAssay Description:Among the compounds of the Examples 1-1 to 1-61, compounds that showed excellent inhibitory activity (inhibitory activity of 85% or more at 20 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
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TargetSerine/threonine-protein kinase mTOR(Human)
Medicinal Bioconvergence Research Center

US Patent
LigandPNGBDBM602741(US11649231, Example 1-37 | (5Z)-5-[(5-methyl-1-phe...)
Affinity DataIC50: 79.9nMAssay Description:Among the compounds of the Examples 1-1 to 1-61, compounds that showed excellent inhibitory activity (inhibitory activity of 85% or more at 20 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
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TargetSerine/threonine-protein kinase mTOR(Human)
Medicinal Bioconvergence Research Center

US Patent
LigandPNGBDBM602744(US11649231, Example 1-56 | (5Z)-5-[[1-(2-pyridyl)...)
Affinity DataIC50: 83nMAssay Description:Among the compounds of the Examples 1-1 to 1-61, compounds that showed excellent inhibitory activity (inhibitory activity of 85% or more at 20 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
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TargetSerine/threonine-protein kinase mTOR(Human)
Medicinal Bioconvergence Research Center

US Patent
LigandPNGBDBM602733(US11649231, Example 1-8 | (5Z)-5-[[1-(4-fluorophen...)
Affinity DataIC50: 86nMAssay Description:Among the compounds of the Examples 1-1 to 1-61, compounds that showed excellent inhibitory activity (inhibitory activity of 85% or more at 20 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
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TargetSerine/threonine-protein kinase mTOR(Human)
Medicinal Bioconvergence Research Center

US Patent
LigandPNGBDBM602740(US11649231, Example 1-35 | (5Z)-5-[[1-(3-pyridyl)p...)
Affinity DataIC50: 87.2nMAssay Description:Among the compounds of the Examples 1-1 to 1-61, compounds that showed excellent inhibitory activity (inhibitory activity of 85% or more at 20 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
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TargetSerine/threonine-protein kinase mTOR(Human)
Medicinal Bioconvergence Research Center

US Patent
LigandPNGBDBM602737(US11649231, Example 1-24 | (5Z)-5-[[1-(4-isopropyl...)
Affinity DataIC50: 89nMAssay Description:Among the compounds of the Examples 1-1 to 1-61, compounds that showed excellent inhibitory activity (inhibitory activity of 85% or more at 20 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
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TargetSerine/threonine-protein kinase mTOR(Human)
Medicinal Bioconvergence Research Center

US Patent
LigandPNGBDBM602739(US11649231, Example 1-33 | (5Z)-5-[[1-(2-pyridyl)p...)
Affinity DataIC50: 89.6nMAssay Description:Among the compounds of the Examples 1-1 to 1-61, compounds that showed excellent inhibitory activity (inhibitory activity of 85% or more at 20 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
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TargetSerine/threonine-protein kinase mTOR(Human)
Medicinal Bioconvergence Research Center

US Patent
LigandPNGBDBM602732(US11649231, Example 1-7 | (5Z)-5-[[1-(3-fluorophen...)
Affinity DataIC50: 91.7nMAssay Description:Among the compounds of the Examples 1-1 to 1-61, compounds that showed excellent inhibitory activity (inhibitory activity of 85% or more at 20 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
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TargetSerine/threonine-protein kinase mTOR(Human)
Medicinal Bioconvergence Research Center

US Patent
LigandPNGBDBM602743(US11649231, Example 1-52 | (5Z)-5-[[1-(3-pyridyl)...)
Affinity DataIC50: 93.4nMAssay Description:Among the compounds of the Examples 1-1 to 1-61, compounds that showed excellent inhibitory activity (inhibitory activity of 85% or more at 20 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
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TargetSerine/threonine-protein kinase mTOR(Human)
Medicinal Bioconvergence Research Center

US Patent
LigandPNGBDBM602747(US11649231, Example 1-61 | (5Z)-5-[[1-(4-pyridyl)p...)
Affinity DataIC50: 94nMAssay Description:Among the compounds of the Examples 1-1 to 1-61, compounds that showed excellent inhibitory activity (inhibitory activity of 85% or more at 20 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
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TargetSerine/threonine-protein kinase mTOR(Human)
Medicinal Bioconvergence Research Center

US Patent
LigandPNGBDBM602738(US11649231, Example 1-30 | (5Z)-5-[[1-(2-methoxyph...)
Affinity DataIC50: 94.2nMAssay Description:Among the compounds of the Examples 1-1 to 1-61, compounds that showed excellent inhibitory activity (inhibitory activity of 85% or more at 20 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
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TargetSerine/threonine-protein kinase mTOR(Human)
Medicinal Bioconvergence Research Center

US Patent
LigandPNGBDBM602745(US11649231, Example 1-57 | (5Z)-5-[[1-(3-pyridyl)p...)
Affinity DataIC50: 103nMAssay Description:Among the compounds of the Examples 1-1 to 1-61, compounds that showed excellent inhibitory activity (inhibitory activity of 85% or more at 20 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
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TargetSerine/threonine-protein kinase mTOR(Human)
Medicinal Bioconvergence Research Center

US Patent
LigandPNGBDBM602742(US11649231, Example 1-39 | (5Z)-5-[(1-phenylpyrazo...)
Affinity DataIC50: 108nMAssay Description:Among the compounds of the Examples 1-1 to 1-61, compounds that showed excellent inhibitory activity (inhibitory activity of 85% or more at 20 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
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TargetSerine/threonine-protein kinase mTOR(Human)
Medicinal Bioconvergence Research Center

US Patent
LigandPNGBDBM602731(US11649231, Example 1-6 | (5Z)-5-[[1-(2-fluorophen...)
Affinity DataIC50: 124nMAssay Description:Among the compounds of the Examples 1-1 to 1-61, compounds that showed excellent inhibitory activity (inhibitory activity of 85% or more at 20 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
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TargetSerine/threonine-protein kinase mTOR(Human)
Medicinal Bioconvergence Research Center

US Patent
LigandPNGBDBM602734(US11649231, Example 1-9 | (5Z)-5-[[1-(2-chlorophen...)
Affinity DataIC50: 162nMAssay Description:Among the compounds of the Examples 1-1 to 1-61, compounds that showed excellent inhibitory activity (inhibitory activity of 85% or more at 20 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
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TargetSerine/threonine-protein kinase mTOR(Human)
Medicinal Bioconvergence Research Center

US Patent
LigandPNGBDBM602746(US11649231, Example 1-59 | (5Z)-5-[[1-(2-pyridyl)p...)
Affinity DataIC50: 216nMAssay Description:Among the compounds of the Examples 1-1 to 1-61, compounds that showed excellent inhibitory activity (inhibitory activity of 85% or more at 20 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent