Compile Data Set for Download or QSAR
Report error Found 113 Enz. Inhib. hit(s) with all data for entry = 11257
TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484080(12-ethyl-8-isopentyl-4-oxa-8,12- diazadispiro[2.1....)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
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TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484081(4-ethyl-9-isopentyl-1-oxa-4,9- diazaspiro[5.5]unde...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484084(8-isopentyl-12-isopropyl-4-oxa-8,12- diazadispiro[...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484086((S)-4-ethyl-9-isopentyl-2-methyl-1-oxa- 4,9-diazas...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484088(8-isopentyl-12-propyl-4-oxa-8,12- diazadispiro[2.1...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484089(12-isobutyl-8-isopentyl-4-oxa-8,12- diazadispiro[2...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484094(4-ethyl-9-isopentyl-2,2-dimethyl-1-oxa- 4,9-diazas...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484095(12-ethyl-8-(4-fluorobenzyl)-4-oxa-8,12- diazadispi...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484096(8-benzyl-12-ethyl-4-oxa-8,12- diazadispiro[2.1.5.3...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484097(8-benzyl-12-methyl-4-oxa-8,12- diazadispiro[2.1.5....)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484098((R)-9-benzyl-4-ethyl-2-methyl-1-oxa- 4,9-diazaspir...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484099(8-benzyl-12-isopropyl-4-oxa-8,12- diazadispiro[2.1...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484101((S)-9-benzyl-4-ethyl-2-methyl-1-oxa- 4,9-diazaspir...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484102(12-ethyl-8-(3-fluorobenzyl)-4-oxa-8,12- diazadispi...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM603043(US11649248, Example 24 | 8-(3,4-difluorobenzyl)-12...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484105(8-benzyl-12-propyl-4-oxa-8,12- diazadispiro[2.1.5....)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484106(8-benzyl-12-isobutyl-4-oxa-8,12- diazadispiro[2.1....)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484111(9-benzyl-4-ethyl-2,2-dimethyl-1-oxa- 4,9-diazaspir...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM603055(US11649248, Example 36 | 8-(2-(3-fluoropyridin-2-y...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM603057(US11649248, Example 38 | (S)-9-(2-(3-fluoropyridin...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484119(8-(2-(3-fluoropyridin-2-yl)ethyl)-12-propyl-4- oxa...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484121(8-(2-(3-fluoropyridin-2-yl)ethyl)-12-isobutyl-4- o...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484124(9-isopentyl-4-isopropyl-2,2- dimethyl-1-oxa-4,9- d...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484125(8-(2,5-difluorophenethyl)-12- isobutyl-4-oxa-8,12-...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484126(12-isobutyl-8-(2-(6- methoxypyridin-2-yl)ethyl)-4-...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484127(9-(3,3-dimethylbutyl)-4- propyl-1-oxa-4,9- diazasp...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484128(9-isopentyl-4-propyl-1-oxa- 4,9-diazaspiro[5.5]und...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484133(9-isopentyl-2,2-dimethyl-4- propyl-1-oxa-4.9- diaz...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484134((S)-9-isopentyl-2-methyl-4- propyl-1-oxa-4,9- diaz...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484146(8-(4-fluorobenzyl)-12-methyl- 4-oxa-8,12- diazadis...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484147(4-ethyl-9-(4-fluorobenzyl)- 2,2-dimethyl-1-oxa-4,9...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484148((S)-9-(4-fluorobenzyl)-4- isopropyl-2-methyl-1-oxa...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484149((R)-4-ethyl-9-(4- fluorobenzyl)-2-methyl-1-oxa- 4,...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484151((S)-9-(4-chlorobenzyl)-4- ethyl-2-methyl-1-oxa-4,9...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484152((R)-9-(4-chlorobenzyl)-4- ethyl-2-methyl-1-oxa-4,9...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484153((R)-4-((4-ethyl-2-methyl-3- oxo-1-oxa-4,9- diazasp...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484154((R)-4-ethyl-9-(4- methoxybenzyl)-2-methyl-1- oxa-4...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484155(9-(4-chlorobenzyl)-4-ethyl- 2,2-dimethyl-1-oxa-4,9...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484156(4-((4-ethyl-2,2-dimethyl-3- oxo-1-oxa-4,9- diazasp...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484160((S)-4-((4-ethyl-2-methyl-3- oxo-1-oxa-4,9- diazasp...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484162((S)-4-((4-isopropyl-2-methyl- 3-oxo-1-oxa-4,9- dia...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484163((R)-9-(4-fluorobenzyl)-2,4- dimethyl-1-oxa-4,9- di...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
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TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484164((S)-4-cyclopropyl-9-(4- fluorobenzyl)-2-methyl-1-o...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
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TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484165((S)-9-benzyl-4-cyclopropyl-2- methyl-1-oxa-4,9- di...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
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TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484166((S)-4-((4-cyclopropyl-2- methyl-3-oxo-1-oxa-4,9- d...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484167((S)-4-((2,4-dimethyl-3-oxo-1- oxa-4,9- diazaspiro[...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484168((S)-9-(4-fluorobenzyl)-2,4- dimethyl-1-oxa-4,9- di...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484180(8-(2-(3-chloropyridin-2- yl)ethyl)-12-isobutyl-4-o...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484181(2-(2-(12-isobutyl-4-oxa-8,12- diazadispiro[2.1.5.3...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484182(8-(2-(3-fluoropyridin-2- yl)ethyl)-12-isopentyl-4-...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
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