Compile Data Set for Download or QSAR
Report error Found 93 Enz. Inhib. hit(s) with all data for entry = 11366
TargetTyrosine-protein kinase Mer [557-882](Human)
Exelixis

US Patent
LigandPNGBDBM609984(US11708367, Compound 30 | 1-N'-[4-(6,7- dimethoxyp...)
Affinity DataIC50: 10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

LigandPNGBDBM609994(US11708367, Compound 67 | 1-N'-[3-fluoro-4-[6-meth...)
Affinity DataIC50: 10nMAssay Description:Human KDR (residues K790-V1356, 55 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.33 mg/mL myelin basic protein, 10 mM magnesium acetate, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Mer [557-882](Human)
Exelixis

US Patent
LigandPNGBDBM609994(US11708367, Compound 67 | 1-N'-[3-fluoro-4-[6-meth...)
Affinity DataIC50: 10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase receptor UFO [473-894](Human)
Exelixis

US Patent
LigandPNGBDBM609994(US11708367, Compound 67 | 1-N'-[3-fluoro-4-[6-meth...)
Affinity DataIC50: 10nMAssay Description:Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKSRGDYMTMQIG (SEQ ID NO. 43), 10 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

LigandPNGBDBM609993(US11708367, Compound 66 | 1-N'-[3-chloro-4-[6-meth...)
Affinity DataIC50: 10nMAssay Description:Human KDR (residues K790-V1356, 55 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.33 mg/mL myelin basic protein, 10 mM magnesium acetate, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Mer [557-882](Human)
Exelixis

US Patent
LigandPNGBDBM609993(US11708367, Compound 66 | 1-N'-[3-chloro-4-[6-meth...)
Affinity DataIC50: 10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase receptor UFO [473-894](Human)
Exelixis

US Patent
LigandPNGBDBM609993(US11708367, Compound 66 | 1-N'-[3-chloro-4-[6-meth...)
Affinity DataIC50: 10nMAssay Description:Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKSRGDYMTMQIG (SEQ ID NO. 43), 10 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Mer [557-882](Human)
Exelixis

US Patent
LigandPNGBDBM610009(US11708367, Compound 117 | 1-N-[4-(6-carbamoyl-7- ...)
Affinity DataIC50: 10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Mer [557-882](Human)
Exelixis

US Patent
LigandPNGBDBM609991(US11708367, Compound 65 | 1-N'-(4-fluorophenyl)-1-...)
Affinity DataIC50: 10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Mer [557-882](Human)
Exelixis

US Patent
LigandPNGBDBM610010(US11708367, Compound 118 | 1-N'-(4-fluorophenyl)-1...)
Affinity DataIC50: 10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase receptor UFO [473-894](Human)
Exelixis

US Patent
LigandPNGBDBM610013(BDBM610014 | US11708367, Compound 121 | 1-N'-(4-fl...)
Affinity DataIC50: 10nMAssay Description:Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKSRGDYMTMQIG (SEQ ID NO. 43), 10 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Mer [557-882](Human)
Exelixis

US Patent
LigandPNGBDBM610013(BDBM610014 | US11708367, Compound 121 | 1-N'-(4-fl...)
Affinity DataIC50: 10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

LigandPNGBDBM609984(US11708367, Compound 30 | 1-N'-[4-(6,7- dimethoxyp...)
Affinity DataIC50: 10nMAssay Description:Human KDR (residues K790-V1356, 55 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.33 mg/mL myelin basic protein, 10 mM magnesium acetate, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase receptor UFO [473-894](Human)
Exelixis

US Patent
LigandPNGBDBM609984(US11708367, Compound 30 | 1-N'-[4-(6,7- dimethoxyp...)
Affinity DataIC50: 10nMAssay Description:Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKSRGDYMTMQIG (SEQ ID NO. 43), 10 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

LigandPNGBDBM609983(US11708367, Compound 29 | 1-N'-[3-chloro-4-(6,7- d...)
Affinity DataIC50: 10nMAssay Description:Human KDR (residues K790-V1356, 55 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.33 mg/mL myelin basic protein, 10 mM magnesium acetate, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Mer [557-882](Human)
Exelixis

US Patent
LigandPNGBDBM609983(US11708367, Compound 29 | 1-N'-[3-chloro-4-(6,7- d...)
Affinity DataIC50: 10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase receptor UFO [473-894](Human)
Exelixis

US Patent
LigandPNGBDBM610013(BDBM610014 | US11708367, Compound 121 | 1-N'-(4-fl...)
Affinity DataIC50: 10nMAssay Description:Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKSRGDYMTMQIG (SEQ ID NO. 43), 10 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

LigandPNGBDBM610019(US11708367, Compound 141 | 1-N'-[3-chloro-4-[(6,7-...)
Affinity DataIC50: 10nMAssay Description:Human KDR (residues K790-V1356, 55 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.33 mg/mL myelin basic protein, 10 mM magnesium acetate, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Mer [557-882](Human)
Exelixis

US Patent
LigandPNGBDBM610019(US11708367, Compound 141 | 1-N'-[3-chloro-4-[(6,7-...)
Affinity DataIC50: 10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

LigandPNGBDBM610018(US11708367, Compound 140 | 1-N'-[4-[(6,7-dimethoxy...)
Affinity DataIC50: 10nMAssay Description:Human KDR (residues K790-V1356, 55 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.33 mg/mL myelin basic protein, 10 mM magnesium acetate, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Mer [557-882](Human)
Exelixis

US Patent
LigandPNGBDBM610018(US11708367, Compound 140 | 1-N'-[4-[(6,7-dimethoxy...)
Affinity DataIC50: 10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase receptor UFO [473-894](Human)
Exelixis

US Patent
LigandPNGBDBM610018(US11708367, Compound 140 | 1-N'-[4-[(6,7-dimethoxy...)
Affinity DataIC50: 10nMAssay Description:Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKSRGDYMTMQIG (SEQ ID NO. 43), 10 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

LigandPNGBDBM610015(US11708367, Compound 139 | 1-N-[4-[(6,7-dimethoxy-...)
Affinity DataIC50: 10nMAssay Description:Human KDR (residues K790-V1356, 55 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.33 mg/mL myelin basic protein, 10 mM magnesium acetate, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Mer [557-882](Human)
Exelixis

US Patent
LigandPNGBDBM610015(US11708367, Compound 139 | 1-N-[4-[(6,7-dimethoxy-...)
Affinity DataIC50: 10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase receptor UFO [473-894](Human)
Exelixis

US Patent
LigandPNGBDBM610015(US11708367, Compound 139 | 1-N-[4-[(6,7-dimethoxy-...)
Affinity DataIC50: 10nMAssay Description:Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKSRGDYMTMQIG (SEQ ID NO. 43), 10 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Mer [557-882](Human)
Exelixis

US Patent
LigandPNGBDBM610013(BDBM610014 | US11708367, Compound 121 | 1-N'-(4-fl...)
Affinity DataIC50: 10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase receptor UFO [473-894](Human)
Exelixis

US Patent
LigandPNGBDBM609982(US11708367, Compound 28 | 1-N-[4-(6,7-dimethoxy- p...)
Affinity DataIC50: 10nMAssay Description:Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKSRGDYMTMQIG (SEQ ID NO. 43), 10 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Mer [557-882](Human)
Exelixis

US Patent
LigandPNGBDBM609982(US11708367, Compound 28 | 1-N-[4-(6,7-dimethoxy- p...)
Affinity DataIC50: 10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

LigandPNGBDBM610013(BDBM610014 | US11708367, Compound 121 | 1-N'-(4-fl...)
Affinity DataIC50: 10nMAssay Description:Human KDR (residues K790-V1356, 55 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.33 mg/mL myelin basic protein, 10 mM magnesium acetate, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Mer [557-882](Human)
Exelixis

US Patent
LigandPNGBDBM610007(US11708367, Compound 115 | 1-N'-(4-fluorophenyl)-1...)
Affinity DataIC50: 55nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

LigandPNGBDBM610007(US11708367, Compound 115 | 1-N'-(4-fluorophenyl)-1...)
Affinity DataIC50: 55nMAssay Description:Human KDR (residues K790-V1356, 55 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.33 mg/mL myelin basic protein, 10 mM magnesium acetate, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase receptor UFO [473-894](Human)
Exelixis

US Patent
LigandPNGBDBM610008(US11708367, Compound 116 | 1-N-[4-[6- (cyclopropyl...)
Affinity DataIC50: 55nMAssay Description:Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKSRGDYMTMQIG (SEQ ID NO. 43), 10 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase receptor UFO [473-894](Human)
Exelixis

US Patent
LigandPNGBDBM610007(US11708367, Compound 115 | 1-N'-(4-fluorophenyl)-1...)
Affinity DataIC50: 55nMAssay Description:Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKSRGDYMTMQIG (SEQ ID NO. 43), 10 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Mer [557-882](Human)
Exelixis

US Patent
LigandPNGBDBM610008(US11708367, Compound 116 | 1-N-[4-[6- (cyclopropyl...)
Affinity DataIC50: 55nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

LigandPNGBDBM610008(US11708367, Compound 116 | 1-N-[4-[6- (cyclopropyl...)
Affinity DataIC50: 55nMAssay Description:Human KDR (residues K790-V1356, 55 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.33 mg/mL myelin basic protein, 10 mM magnesium acetate, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

LigandPNGBDBM610005(US11708367, Compound 104 | 1-N'-(4-fluorophenyl)-1...)
Affinity DataIC50: 55nMAssay Description:Human KDR (residues K790-V1356, 55 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.33 mg/mL myelin basic protein, 10 mM magnesium acetate, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Mer [557-882](Human)
Exelixis

US Patent
LigandPNGBDBM610005(US11708367, Compound 104 | 1-N'-(4-fluorophenyl)-1...)
Affinity DataIC50: 55nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase receptor UFO [473-894](Human)
Exelixis

US Patent
LigandPNGBDBM610005(US11708367, Compound 104 | 1-N'-(4-fluorophenyl)-1...)
Affinity DataIC50: 55nMAssay Description:Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKSRGDYMTMQIG (SEQ ID NO. 43), 10 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Mer [557-882](Human)
Exelixis

US Patent
LigandPNGBDBM610002(US11708367, Compound 91 | 1-N'-(4-fluorophenyl)-1-...)
Affinity DataIC50: 55nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase receptor UFO [473-894](Human)
Exelixis

US Patent
LigandPNGBDBM610009(US11708367, Compound 117 | 1-N-[4-(6-carbamoyl-7- ...)
Affinity DataIC50: 55nMAssay Description:Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKSRGDYMTMQIG (SEQ ID NO. 43), 10 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

LigandPNGBDBM610009(US11708367, Compound 117 | 1-N-[4-(6-carbamoyl-7- ...)
Affinity DataIC50: 55nMAssay Description:Human KDR (residues K790-V1356, 55 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.33 mg/mL myelin basic protein, 10 mM magnesium acetate, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase receptor UFO [473-894](Human)
Exelixis

US Patent
LigandPNGBDBM610010(US11708367, Compound 118 | 1-N'-(4-fluorophenyl)-1...)
Affinity DataIC50: 55nMAssay Description:Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKSRGDYMTMQIG (SEQ ID NO. 43), 10 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

LigandPNGBDBM610010(US11708367, Compound 118 | 1-N'-(4-fluorophenyl)-1...)
Affinity DataIC50: 55nMAssay Description:Human KDR (residues K790-V1356, 55 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.33 mg/mL myelin basic protein, 10 mM magnesium acetate, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase receptor UFO [473-894](Human)
Exelixis

US Patent
LigandPNGBDBM610011(US11708367, Compound 119 | tert-butyl (2R)-2-[[[4-...)
Affinity DataIC50: 55nMAssay Description:Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKSRGDYMTMQIG (SEQ ID NO. 43), 10 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Mer [557-882](Human)
Exelixis

US Patent
LigandPNGBDBM610011(US11708367, Compound 119 | tert-butyl (2R)-2-[[[4-...)
Affinity DataIC50: 55nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase receptor UFO [473-894](Human)
Exelixis

US Patent
LigandPNGBDBM610012(US11708367, Compound 120 | tert-butyl (2S)-2-[[[4-...)
Affinity DataIC50: 55nMAssay Description:Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKSRGDYMTMQIG (SEQ ID NO. 43), 10 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Mer [557-882](Human)
Exelixis

US Patent
LigandPNGBDBM610012(US11708367, Compound 120 | tert-butyl (2S)-2-[[[4-...)
Affinity DataIC50: 55nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

LigandPNGBDBM610013(BDBM610014 | US11708367, Compound 121 | 1-N'-(4-fl...)
Affinity DataIC50: 55nMAssay Description:Human KDR (residues K790-V1356, 55 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.33 mg/mL myelin basic protein, 10 mM magnesium acetate, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
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TargetTyrosine-protein kinase receptor UFO [473-894](Human)
Exelixis

US Patent
LigandPNGBDBM610019(US11708367, Compound 141 | 1-N'-[3-chloro-4-[(6,7-...)
Affinity DataIC50: 55nMAssay Description:Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKSRGDYMTMQIG (SEQ ID NO. 43), 10 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
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TargetTyrosine-protein kinase Mer [557-882](Human)
Exelixis

US Patent
LigandPNGBDBM609990(US11708367, Compound 57 | 1-N-[4-(6-cyano-7- metho...)
Affinity DataIC50: 55nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
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