Compile Data Set for Download or QSAR
Report error Found 55 Enz. Inhib. hit(s) with all data for entry = 12047
TargetProlyl hydroxylase EGLN2(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674473(2-(2-phenoxy-5-hydroxy-8-bromo-1,7-naphthyridine-6...)
Affinity DataIC50: 40.3nMAssay Description:VHL/elongin B/elongin C were constructed, expressed and purified, and VHL was labeled. PHD1, PHD2 and PHD3 were constructed, expressed and purified. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetProlyl hydroxylase EGLN2(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674471(2-(2-phenoxy-5-hydroxy-8-chloro-1,7-naphthyridine-...)
Affinity DataIC50: 46.9nMAssay Description:VHL/elongin B/elongin C were constructed, expressed and purified, and VHL was labeled. PHD1, PHD2 and PHD3 were constructed, expressed and purified. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetProlyl hydroxylase EGLN3(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674471(2-(2-phenoxy-5-hydroxy-8-chloro-1,7-naphthyridine-...)
Affinity DataIC50: 72.8nMAssay Description:VHL/elongin B/elongin C were constructed, expressed and purified, and VHL was labeled. PHD1, PHD2 and PHD3 were constructed, expressed and purified. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetProlyl hydroxylase EGLN3(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674473(2-(2-phenoxy-5-hydroxy-8-bromo-1,7-naphthyridine-6...)
Affinity DataIC50: 95.6nMAssay Description:VHL/elongin B/elongin C were constructed, expressed and purified, and VHL was labeled. PHD1, PHD2 and PHD3 were constructed, expressed and purified. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetEgl nine homolog 1(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674471(2-(2-phenoxy-5-hydroxy-8-chloro-1,7-naphthyridine-...)
Affinity DataIC50: 207nMAssay Description:VHL/elongin B/elongin C were constructed, expressed and purified, and VHL was labeled. PHD1, PHD2 and PHD3 were constructed, expressed and purified. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetProlyl hydroxylase EGLN2(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM50286245(CHEMBL4163070 | US11981669, Comparative Example 1)
Affinity DataIC50: 273nMAssay Description:VHL/elongin B/elongin C were constructed, expressed and purified, and VHL was labeled. PHD1, PHD2 and PHD3 were constructed, expressed and purified. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetProlyl hydroxylase EGLN2(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM292137(US10100051, Compound 6 | 2-(5-hydroxy-2-phenoxy-1,...)
Affinity DataIC50: 335nMAssay Description:VHL/elongin B/elongin C were constructed, expressed and purified, and VHL was labeled. PHD1, PHD2 and PHD3 were constructed, expressed and purified. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetEgl nine homolog 1(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674473(2-(2-phenoxy-5-hydroxy-8-bromo-1,7-naphthyridine-6...)
Affinity DataIC50: 353nMAssay Description:VHL/elongin B/elongin C were constructed, expressed and purified, and VHL was labeled. PHD1, PHD2 and PHD3 were constructed, expressed and purified. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetProlyl hydroxylase EGLN2(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM50605644(CHEMBL5209093 | US11981669, Comparative Example 3)
Affinity DataIC50: 452nMAssay Description:VHL/elongin B/elongin C were constructed, expressed and purified, and VHL was labeled. PHD1, PHD2 and PHD3 were constructed, expressed and purified. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetProlyl hydroxylase EGLN3(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM292137(US10100051, Compound 6 | 2-(5-hydroxy-2-phenoxy-1,...)
Affinity DataIC50: 492nMAssay Description:VHL/elongin B/elongin C were constructed, expressed and purified, and VHL was labeled. PHD1, PHD2 and PHD3 were constructed, expressed and purified. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetProlyl hydroxylase EGLN3(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM50605644(CHEMBL5209093 | US11981669, Comparative Example 3)
Affinity DataIC50: 544nMAssay Description:VHL/elongin B/elongin C were constructed, expressed and purified, and VHL was labeled. PHD1, PHD2 and PHD3 were constructed, expressed and purified. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetProlyl hydroxylase EGLN3(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM50286245(CHEMBL4163070 | US11981669, Comparative Example 1)
Affinity DataIC50: 561nMAssay Description:VHL/elongin B/elongin C were constructed, expressed and purified, and VHL was labeled. PHD1, PHD2 and PHD3 were constructed, expressed and purified. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetEgl nine homolog 1(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM50286245(CHEMBL4163070 | US11981669, Comparative Example 1)
Affinity DataIC50: 770nMAssay Description:VHL/elongin B/elongin C were constructed, expressed and purified, and VHL was labeled. PHD1, PHD2 and PHD3 were constructed, expressed and purified. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetEgl nine homolog 1(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM292137(US10100051, Compound 6 | 2-(5-hydroxy-2-phenoxy-1,...)
Affinity DataIC50: 807nMAssay Description:VHL/elongin B/elongin C were constructed, expressed and purified, and VHL was labeled. PHD1, PHD2 and PHD3 were constructed, expressed and purified. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetEgl nine homolog 1(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM50605644(CHEMBL5209093 | US11981669, Comparative Example 3)
Affinity DataIC50: 951nMAssay Description:VHL/elongin B/elongin C were constructed, expressed and purified, and VHL was labeled. PHD1, PHD2 and PHD3 were constructed, expressed and purified. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674478(2-(2-(3-chlorophenoxy)-5-hydroxy-8-bromo-1,7-napht...)
Affinity DataIC50: 3.79E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 2C19(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674474(2-(2-(2-chlorophenoxy)-5-hydroxy-8-chloro-1,7-naph...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 2C9(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674474(2-(2-(2-chlorophenoxy)-5-hydroxy-8-chloro-1,7-naph...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674474(2-(2-(2-chlorophenoxy)-5-hydroxy-8-chloro-1,7-naph...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674474(2-(2-(2-chlorophenoxy)-5-hydroxy-8-chloro-1,7-naph...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674473(2-(2-phenoxy-5-hydroxy-8-bromo-1,7-naphthyridine-6...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 2C19(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674473(2-(2-phenoxy-5-hydroxy-8-bromo-1,7-naphthyridine-6...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674474(2-(2-(2-chlorophenoxy)-5-hydroxy-8-chloro-1,7-naph...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674473(2-(2-phenoxy-5-hydroxy-8-bromo-1,7-naphthyridine-6...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674477(2-(2-(3-chlorophenoxy)-5-hydroxy-8-chloro-1,7-naph...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674475(2-(2-(2-chlorophenoxy)-5-hydroxy-8-bromo-1,7-napht...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 2C19(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674477(2-(2-(3-chlorophenoxy)-5-hydroxy-8-chloro-1,7-naph...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 2C9(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674477(2-(2-(3-chlorophenoxy)-5-hydroxy-8-chloro-1,7-naph...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 2C9(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674475(2-(2-(2-chlorophenoxy)-5-hydroxy-8-bromo-1,7-napht...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674475(2-(2-(2-chlorophenoxy)-5-hydroxy-8-bromo-1,7-napht...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674475(2-(2-(2-chlorophenoxy)-5-hydroxy-8-bromo-1,7-napht...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 2C19(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674475(2-(2-(2-chlorophenoxy)-5-hydroxy-8-bromo-1,7-napht...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674471(2-(2-phenoxy-5-hydroxy-8-chloro-1,7-naphthyridine-...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674471(2-(2-phenoxy-5-hydroxy-8-chloro-1,7-naphthyridine-...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 2C9(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674473(2-(2-phenoxy-5-hydroxy-8-bromo-1,7-naphthyridine-6...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674473(2-(2-phenoxy-5-hydroxy-8-bromo-1,7-naphthyridine-6...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674471(2-(2-phenoxy-5-hydroxy-8-chloro-1,7-naphthyridine-...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 2C19(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674471(2-(2-phenoxy-5-hydroxy-8-chloro-1,7-naphthyridine-...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 2C9(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674471(2-(2-phenoxy-5-hydroxy-8-chloro-1,7-naphthyridine-...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674480(2-(2-(4-chlorophenoxy)-5-hydroxy-8-bromo-1,7-napht...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674478(2-(2-(3-chlorophenoxy)-5-hydroxy-8-bromo-1,7-napht...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 2C19(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674478(2-(2-(3-chlorophenoxy)-5-hydroxy-8-bromo-1,7-napht...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674479(2-(2-(4-chlorophenoxy)-5-hydroxy-8-chloro-1,7-naph...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674478(2-(2-(3-chlorophenoxy)-5-hydroxy-8-bromo-1,7-napht...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674477(2-(2-(3-chlorophenoxy)-5-hydroxy-8-chloro-1,7-naph...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674477(2-(2-(3-chlorophenoxy)-5-hydroxy-8-chloro-1,7-naph...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 2C9(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674478(2-(2-(3-chlorophenoxy)-5-hydroxy-8-bromo-1,7-napht...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 2C9(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674480(2-(2-(4-chlorophenoxy)-5-hydroxy-8-bromo-1,7-napht...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674480(2-(2-(4-chlorophenoxy)-5-hydroxy-8-bromo-1,7-napht...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674480(2-(2-(4-chlorophenoxy)-5-hydroxy-8-bromo-1,7-napht...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

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