Compile Data Set for Download or QSAR
Report error Found 300 Enz. Inhib. hit(s) with all data for entry = 12650
TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717711(US12215173, Compound 13-22)
Affinity DataIC50: 0.0960nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
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TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717776(US12215173, Compound 127)
Affinity DataIC50: 0.100nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717719(US12215173, Compound 13-30)
Affinity DataIC50: 0.150nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717765(US12215173, Compound 71)
Affinity DataIC50: 0.160nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
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TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717764(US12215173, Compound 70)
Affinity DataIC50: 0.170nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetDelta-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM50370067(CHEMBL1237164 | US12215173, Compound Naltrindole)
Affinity DataIC50: 0.183nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2025
Entry Details
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PDB3D3D Structure (crystal)
TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717756(US12215173, Compound 35)
Affinity DataIC50: 0.190nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717750(US12215173, Compound 13-62)
Affinity DataIC50: 0.200nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717704(US12215173, Compound 13-14)
Affinity DataIC50: 0.210nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
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TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717730(US12215173, Compound 13-41)
Affinity DataIC50: 0.210nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
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TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717743(US12215173, Compound 13-54)
Affinity DataIC50: 0.210nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
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TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717728(US12215173, Compound 13-39)
Affinity DataIC50: 0.230nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717789(US12215173, Compound 184)
Affinity DataIC50: 0.25nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
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TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717717(US12215173, Compound 13-28)
Affinity DataIC50: 0.260nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717736(US12215173, Compound 13-47)
Affinity DataIC50: 0.270nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717740(US12215173, Compound 13-51)
Affinity DataIC50: 0.270nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717720(US12215173, Compound 13-31)
Affinity DataIC50: 0.280nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717718(US12215173, Compound 13-29)
Affinity DataIC50: 0.290nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717747(US12215173, Compound 13-58)
Affinity DataIC50: 0.290nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717727(US12215173, Compound 13-38)
Affinity DataIC50: 0.300nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717729(US12215173, Compound 13-40)
Affinity DataIC50: 0.300nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717724(US12215173, Compound 13-35)
Affinity DataIC50: 0.310nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717735(US12215173, Compound 13-46)
Affinity DataIC50: 0.310nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717709(US12215173, Compound 13-19)
Affinity DataIC50: 0.330nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717732(US12215173, Compound 13-43)
Affinity DataIC50: 0.330nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717758(US12215173, Compound 45)
Affinity DataIC50: 0.330nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717773(US12215173, Compound 118)
Affinity DataIC50: 0.330nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717744(US12215173, Compound 13-55)
Affinity DataIC50: 0.350nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717745(US12215173, Compound 13-56)
Affinity DataIC50: 0.350nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717737(US12215173, Compound 13-48)
Affinity DataIC50: 0.360nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717748(US12215173, Compound 13-59)
Affinity DataIC50: 0.360nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717775(US12215173, Compound 126)
Affinity DataIC50: 0.360nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717706(US12215173, Compound 13-16)
Affinity DataIC50: 0.370nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717739(US12215173, Compound 13-50)
Affinity DataIC50: 0.370nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717759(US12215173, Compound 50)
Affinity DataIC50: 0.390nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717788(US12215173, Compound 181)
Affinity DataIC50: 0.400nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717699(US12215173, Compound 13-9)
Affinity DataIC50: 0.410nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717705(US12215173, Compound 13-15)
Affinity DataIC50: 0.410nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717757(US12215173, Compound 40)
Affinity DataIC50: 0.410nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717749(US12215173, Compound 13-60)
Affinity DataIC50: 0.420nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetMu-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717689(US12215173, Compound DAMGO)
Affinity DataIC50: 0.426nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717734(US12215173, Compound 13-45)
Affinity DataIC50: 0.430nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717753(US12215173, Compound 13-65)
Affinity DataIC50: 0.450nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717760(US12215173, Compound 55)
Affinity DataIC50: 0.450nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717733(US12215173, Compound 13-44)
Affinity DataIC50: 0.460nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717738(US12215173, Compound 13-49)
Affinity DataIC50: 0.460nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717752(US12215173, Compound 13-64)
Affinity DataIC50: 0.470nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717731(US12215173, Compound 13-42)
Affinity DataIC50: 0.480nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717725(US12215173, Compound 13-36)
Affinity DataIC50: 0.490nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
Entry Details
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TargetKappa-type opioid receptor(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM717713(US12215173, Compound 13-24)
Affinity DataIC50: 0.520nMAssay Description:The assay buffers used for opioid receptor binding studies were 50 mM Tris HCl (pH 7.4) for KOR, 50 mM Tris HCl (pH 7.4) with 5 mM MgCl2 for MOR, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2025
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