Compile Data Set for Download or QSAR
Report error Found 216 Enz. Inhib. hit(s) with all data for entry = 12761
TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726177(US12247004, Compound ANASIA-041-1)
Affinity DataIC50: 17.7nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726265(US12247004, Compound ANASIA-103-1)
Affinity DataIC50: 19.5nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726297(US12247004, Compound ANASIA-124-1)
Affinity DataIC50: 21.3nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726132(US12247004, Compound ANASIA-011-1)
Affinity DataIC50: 26.2nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726113(US12247004, Compound ANASIA-002-1)
Affinity DataIC50: 27.5nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726261(US12247004, Compound ANASIA-100-1)
Affinity DataIC50: 27.8nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726251(US12247004, Compound ANASIA-095-1)
Affinity DataIC50: 29nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726126(US12247004, Compound ANASIA-008-1)
Affinity DataIC50: 30.6nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726260(US12247004, Compound ANASIA-100)
Affinity DataIC50: 32.8nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726230(US12247004, Compound ANASIA-081-1)
Affinity DataIC50: 33.9nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726292(US12247004, Compound ANASIA-121-1)
Affinity DataIC50: 41.7nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726206(US12247004, Compound ANASIA-062-1)
Affinity DataIC50: 47.5nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726247(US12247004, Compound ANASIA-092-1)
Affinity DataIC50: 48.4nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726140(US12247004, Compound ANASIA-015-1)
Affinity DataIC50: 56.5nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726116(US12247004, Compound ANASIA-003-1)
Affinity DataIC50: 61.5nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726281(US12247004, Compound ANASIA-114-1)
Affinity DataIC50: 61.8nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726123(US12247004, Compound ANASIA-007-1)
Affinity DataIC50: 63.3nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726183(US12247004, Compound ANASIA-044-1)
Affinity DataIC50: 71nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726317(US12247004, Compound ANASIA-136-1)
Affinity DataIC50: 71.8nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726131(US12247004, Compound ANASIA-011)
Affinity DataIC50: 71.9nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726257(US12247004, Compound ANASIA-099)
Affinity DataIC50: 72.2nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726240(US12247004, Compound ANASIA-088-1)
Affinity DataIC50: 75.3nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726188(US12247004, Compound ANASIA-047-1)
Affinity DataIC50: 76.4nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726138(US12247004, Compound ANASIA-014-1)
Affinity DataIC50: 81.1nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726135(US12247004, Compound ANASIA-012-1)
Affinity DataIC50: 87.4nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726118(US12247004, Compound ANASIA-004)
Affinity DataIC50: 91.6nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726115(US12247004, Compound ANASIA-003)
Affinity DataIC50: 92.9nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726312(US12247004, Compound ANASIA-133-1)
Affinity DataIC50: 97.3nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726219(US12247004, Compound ANASIA-074)
Affinity DataIC50: 99.2nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726288(US12247004, Compound ANASIA-119-1)
Affinity DataIC50: 99.7nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726271(US12247004, Compound ANASIA-107-1)
Affinity DataIC50: 106nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726112(US12247004, Compound ANASIA-002)
Affinity DataIC50: 110nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726181(US12247004, Compound ANASIA-043-1)
Affinity DataIC50: 112nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726258(US12247004, Compound ANASIA-099-1)
Affinity DataIC50: 124nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726273(US12247004, Compound ANASIA-108-1)
Affinity DataIC50: 127nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726154(US12247004, Compound ANASIA-024-1)
Affinity DataIC50: 141nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726213(US12247004, Compound ANASIA-068)
Affinity DataIC50: 141nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726215(US12247004, Compound ANASIA-070)
Affinity DataIC50: 143nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726125(US12247004, Compound ANASIA-008)
Affinity DataIC50: 144nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726145(US12247004, Compound ANASIA-017)
Affinity DataIC50: 145nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726255(US12247004, Compound ANASIA-098-1)
Affinity DataIC50: 148nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726129(US12247004, Compound ANASIA-009-2)
Affinity DataIC50: 149nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726121(US12247004, Compound ANASIA-005-2)
Affinity DataIC50: 151nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726134(US12247004, Compound ANASIA-012)
Affinity DataIC50: 155nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726233(US12247004, Compound ANASIA-083-1)
Affinity DataIC50: 157nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726294(US12247004, Compound ANASIA-122-1)
Affinity DataIC50: 167nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726216(US12247004, Compound ANASIA-071)
Affinity DataIC50: 173nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726304(US12247004, Compound ANASIA-127-2)
Affinity DataIC50: 192nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726242(US12247004, Compound ANASIA-089-1)
Affinity DataIC50: 195nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726244(US12247004, Compound ANASIA-090)
Affinity DataIC50: 199nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
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