Compile Data Set for Download or QSAR
Report error Found 170 Enz. Inhib. hit(s) with all data for entry = 13305
TargetNT-3 growth factor receptor(Human)
Tyk Medicines

US Patent
LigandPNGBDBM139540(US8889696, Staurosporine | US9051313, Staurosporin...)
Affinity DataIC50: 0.106nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Tyk Medicines

US Patent
LigandPNGBDBM139540(US8889696, Staurosporine | US9051313, Staurosporin...)
Affinity DataIC50: 0.246nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Tyk Medicines

US Patent
LigandPNGBDBM139540(US8889696, Staurosporine | US9051313, Staurosporin...)
Affinity DataIC50: 0.473nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS (G2032R)(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775584(US12435089, Example 55)
Affinity DataIC50: 0.5nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS (G2032R)(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775561(US12435089, Example 4)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775584(US12435089, Example 55)
Affinity DataIC50: 0.5nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetNT-3 growth factor receptor(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775583(US12435089, Example 52)
Affinity DataIC50: 0.5nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775584(US12435089, Example 55)
Affinity DataIC50: 0.5nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775561(US12435089, Example 4)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775586(US12435089, Example 57)
Affinity DataIC50: 0.5nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetNT-3 growth factor receptor(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775585(US12435089, Example 54)
Affinity DataIC50: 0.5nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775585(US12435089, Example 54)
Affinity DataIC50: 0.5nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775561(US12435089, Example 4)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetNT-3 growth factor receptor(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775584(US12435089, Example 55)
Affinity DataIC50: 0.5nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS (G2032R)(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775585(US12435089, Example 54)
Affinity DataIC50: 0.5nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetNT-3 growth factor receptor(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775582(US12435089, Example 51)
Affinity DataIC50: 0.5nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775582(US12435089, Example 51)
Affinity DataIC50: 0.5nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775582(US12435089, Example 51)
Affinity DataIC50: 0.5nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775572(US12435089, Example 28)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS (G2032R)(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775582(US12435089, Example 51)
Affinity DataIC50: 0.5nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775583(US12435089, Example 52)
Affinity DataIC50: 0.5nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775590(US12435089, Example 68)
Affinity DataIC50: 0.5nMAssay Description:Compounds were dissolved in DMSO to a stock concentration of 10 mM and tested in 10-dose IC50 mode, in triplicate, with a 3-fold serial dilution star...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS (G2032R)(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775562(US12435089, Example 5)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetNT-3 growth factor receptor(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775588(US12435089, Example 66)
Affinity DataIC50: 0.5nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Tyk Medicines

US Patent
LigandPNGBDBM50649925(CHEMBL5624610 | US12435089, Example 10)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775562(US12435089, Example 5)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Tyk Medicines

US Patent
LigandPNGBDBM50649925(CHEMBL5624610 | US12435089, Example 10)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775590(US12435089, Example 68)
Affinity DataIC50: 0.5nMAssay Description:Compounds were dissolved in DMSO to a stock concentration of 10 mM and tested in 10-dose IC50 mode, in triplicate, with a 3-fold serial dilution star...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS (G2032R)(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775590(US12435089, Example 68)
Affinity DataIC50: 0.5nMAssay Description:Compounds were dissolved in DMSO to a stock concentration of 10 mM and tested in 10-dose IC50 mode, in triplicate, with a 3-fold serial dilution star...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS (G2032R)(Human)
Tyk Medicines

US Patent
LigandPNGBDBM50649925(CHEMBL5624610 | US12435089, Example 10)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775587(US12435089, Example 65)
Affinity DataIC50: 0.5nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetNT-3 growth factor receptor(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775561(US12435089, Example 4)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetNT-3 growth factor receptor(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775586(US12435089, Example 57)
Affinity DataIC50: 0.5nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS (G2032R)(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775587(US12435089, Example 65)
Affinity DataIC50: 0.5nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS (G2032R)(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775586(US12435089, Example 57)
Affinity DataIC50: 0.5nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775561(US12435089, Example 4)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS (G2032R)(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775588(US12435089, Example 66)
Affinity DataIC50: 0.5nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775562(US12435089, Example 5)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775588(US12435089, Example 66)
Affinity DataIC50: 0.5nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetNT-3 growth factor receptor(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775587(US12435089, Example 65)
Affinity DataIC50: 0.5nMAssay Description:Compounds as a powder were dissolved in dimethyl sulfoxide to make a 10 mM stock. Compounds were tested in 10-dose IC50 triplicate mode with a 3-fold...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetNT-3 growth factor receptor(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775590(US12435089, Example 68)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775590(US12435089, Example 68)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS (G2032R)(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775591(US12435089, Example 69)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775591(US12435089, Example 69)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor [G595R](Human)
Tyk Medicines

US Patent
LigandPNGBDBM775590(US12435089, Example 68)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetNT-3 growth factor receptor(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775563(US12435089, Example 9)
Affinity DataIC50: 0.5nMAssay Description:Serial dilutions of the compound were prepared with 10% DMSO, and 5 μl of each dilution was added to a 50 μl reaction vessel to result in a...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetNT-3 growth factor receptor(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775562(US12435089, Example 5)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetNT-3 growth factor receptor(Human)
Tyk Medicines

US Patent
LigandPNGBDBM50649925(CHEMBL5624610 | US12435089, Example 10)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775563(US12435089, Example 9)
Affinity DataIC50: 0.5nMAssay Description:Serial dilutions of the compound were prepared with 10% DMSO, and 5 μl of each dilution was added to a 50 μl reaction vessel to result in a...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Tyk Medicines

US Patent
LigandPNGBDBM50649925(CHEMBL5624610 | US12435089, Example 10)
Affinity DataIC50: 0.5nMAssay Description:Serial dilutions of the compound were prepared with 10% DMSO, and 5 μl of each dilution was added to a 50 μl reaction vessel to result in a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

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