Compile Data Set for Download or QSAR
Report error Found 349 Enz. Inhib. hit(s) with all data for entry = 547
TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM264072(US20230270730, Compound A-1 | US20240327355, Compo...)
Affinity DataIC50: 1nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM350231(US20230270730, Compound A-13 | US11964950, Compoun...)
Affinity DataIC50: 1nMAssay Description:The test compound, CRAF (Thermo Fisher Scientific Inc.), MEK1 (Thermo Fisher Scientific Inc.) and ERK2 (Carna Biosciences, Inc.) were mixed in ATP-co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614276(US20230270730, Compound A-29 | US11964950, Compoun...)
Affinity DataIC50: 1nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614317(US20230270730, Compound D-1 | US11964950, Compound...)
Affinity DataIC50: 1nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614319(US20230270730, Compound D-3 | US11964950, Compound...)
Affinity DataIC50: 1nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614347(US20230270730, Compound E-13 | US11964950, Compoun...)
Affinity DataIC50: 1nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614412(US20230270730, Compound N-1 | US11964950, Compound...)
Affinity DataIC50: 1nMAssay Description:The test compound, CRAF (Thermo Fisher Scientific Inc.), MEK1 (Thermo Fisher Scientific Inc.) and ERK2 (Carna Biosciences, Inc.) were mixed in ATP-co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614413(US20230270730, Compound N-2 | US11964950, Compound...)
Affinity DataIC50: 1nMAssay Description:The test compound, CRAF (Thermo Fisher Scientific Inc.), MEK1 (Thermo Fisher Scientific Inc.) and ERK2 (Carna Biosciences, Inc.) were mixed in ATP-co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614413(US20230270730, Compound N-2 | US11964950, Compound...)
Affinity DataIC50: 1nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM319594(US20230270730, Compound A-4 | US11964950, Compound...)
Affinity DataIC50: 2nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM350232(US20230270730, Compound A-14 | US11964950, Compoun...)
Affinity DataIC50: 2nMAssay Description:The test compound, CRAF (Thermo Fisher Scientific Inc.), MEK1 (Thermo Fisher Scientific Inc.) and ERK2 (Carna Biosciences, Inc.) were mixed in ATP-co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614267(US20230270730, Compound A-20 | US11964950, Compoun...)
Affinity DataIC50: 2nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614269(US20230270730, Compound A-22)
Affinity DataIC50: 2nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614272(US20230270730, Compound A-25 | US11964950, Compoun...)
Affinity DataIC50: 2nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614280(US20230270730, Compound A-33 | US11964950, Compoun...)
Affinity DataIC50: 2nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614287(US20230270730, Compound A-40 | US11964950, Compoun...)
Affinity DataIC50: 2nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614292(US20230270730, Compound A-44 | US11964950, Compoun...)
Affinity DataIC50: 2nMAssay Description:The test compound, CRAF (Thermo Fisher Scientific Inc.), MEK1 (Thermo Fisher Scientific Inc.) and ERK2 (Carna Biosciences, Inc.) were mixed in ATP-co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614293(US20230270730, Compound A-45 | US11964950, Compoun...)
Affinity DataIC50: 2nMAssay Description:The test compound, CRAF (Thermo Fisher Scientific Inc.), MEK1 (Thermo Fisher Scientific Inc.) and ERK2 (Carna Biosciences, Inc.) were mixed in ATP-co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614296(US20230270730, Compound B-1 | US11964950, Compound...)
Affinity DataIC50: 2nMAssay Description:The test compound, CRAF (Thermo Fisher Scientific Inc.), MEK1 (Thermo Fisher Scientific Inc.) and ERK2 (Carna Biosciences, Inc.) were mixed in ATP-co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614303(US20230270730, Compound B-9 | US11964950, Compound...)
Affinity DataIC50: 2nMAssay Description:The test compound, CRAF (Thermo Fisher Scientific Inc.), MEK1 (Thermo Fisher Scientific Inc.) and ERK2 (Carna Biosciences, Inc.) were mixed in ATP-co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614312(US20230270730, Compound C-2 | US11964950, Compound...)
Affinity DataIC50: 2nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614342(US20230270730, Compound E-8 | US11964950, Compound...)
Affinity DataIC50: 2nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614373(US20230270730, Compound H-1 | US11964950, Compound...)
Affinity DataIC50: 2nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614374(US20230270730, Compound H-2 | US11964950, Compound...)
Affinity DataIC50: 2nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614375(US20230270730, Compound H-3)
Affinity DataIC50: 2nMAssay Description:The test compound, CRAF (Thermo Fisher Scientific Inc.), MEK1 (Thermo Fisher Scientific Inc.) and ERK2 (Carna Biosciences, Inc.) were mixed in ATP-co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614377(US20230270730, Compound H-5 | US11964950, Compound...)
Affinity DataIC50: 2nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614380(US20230270730, Compound I-3 | US11964950, Compound...)
Affinity DataIC50: 2nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614389(US20230270730, Compound J-8 | US11964950, Compound...)
Affinity DataIC50: 2nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614410(US20230270730, Compound L-1)
Affinity DataIC50: 2nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614412(US20230270730, Compound N-1 | US11964950, Compound...)
Affinity DataIC50: 2nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614415(US20230270730, Compound P-1 | US11964950, Compound...)
Affinity DataIC50: 2nMAssay Description:The test compound, CRAF (Thermo Fisher Scientific Inc.), MEK1 (Thermo Fisher Scientific Inc.) and ERK2 (Carna Biosciences, Inc.) were mixed in ATP-co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM312293(US20230270730, Compound A-2 | US11964950, Compound...)
Affinity DataIC50: 3nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM319604(US20230270730, Compound A-8 | US11964950, Compound...)
Affinity DataIC50: 3nMAssay Description:The test compound, CRAF (Thermo Fisher Scientific Inc.), MEK1 (Thermo Fisher Scientific Inc.) and ERK2 (Carna Biosciences, Inc.) were mixed in ATP-co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM350231(US20230270730, Compound A-13 | US11964950, Compoun...)
Affinity DataIC50: 3nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM350232(US20230270730, Compound A-14 | US11964950, Compoun...)
Affinity DataIC50: 3nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM360431(US20230270730, Compound A-16 | US11964950, Compoun...)
Affinity DataIC50: 3nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614266(US20230270730, Compound A-19 | US11964950, Compoun...)
Affinity DataIC50: 3nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614271(US20230270730, Compound A-24 | US11964950, Compoun...)
Affinity DataIC50: 3nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614281(US20230270730, Compound A-34 | US11964950, Compoun...)
Affinity DataIC50: 3nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614285(US20230270730, Compound A-38 | US11964950, Compoun...)
Affinity DataIC50: 3nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614297(US20230270730, Compound B-2 | US11964950, Compound...)
Affinity DataIC50: 3nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614305(US20230270730, Compound B-11 | US11964950, Compoun...)
Affinity DataIC50: 3nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614313(US20230270730, Compound C-3 | US11964950, Compound...)
Affinity DataIC50: 3nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614315(US20230270730, Compound C-5 | US11964950, Compound...)
Affinity DataIC50: 3nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614318(US20230270730, Compound D-2 | US11964950, Compound...)
Affinity DataIC50: 3nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614320(US20230270730, Compound D-4 | US11964950, Compound...)
Affinity DataIC50: 3nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614328(US20230270730, Compound D-11 | US11964950, Compoun...)
Affinity DataIC50: 3nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614365(US20230270730, Compound G-2 | US11964950, Compound...)
Affinity DataIC50: 3nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614378(US20230270730, Compound I-1 | US11964950, Compound...)
Affinity DataIC50: 3nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM614379(US20230270730, Compound I-2 | US11964950, Compound...)
Affinity DataIC50: 3nMAssay Description:The test compound, BRAF (Eurofins Genomics KK.) and MEK1 (Thermo Fisher Scientific Inc.) were mixed in ATP-containing buffer and reacted for 90 minut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
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