Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 11454
TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617447(US20230285377, Example 31)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617448(US20230285377, Example 32)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617412(US20230285377, Example 1)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617418(US20230285377, Example 6)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617455(US20230285377, Example 39)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617419(US20230285377, Example 7)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617413(US20230285377, Example 2)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617451(US20230285377, Example 35)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617452(US20230285377, Example 36)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617415(US20230285377, Example 4)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617416(US20230285377, Example 5)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617426(US20230285377, Example 14)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617428(US20230285377, Example 16)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617422(US20230285377, Example 10)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617423(US20230285377, Example 11)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617424(US20230285377, Example 12)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617460(US20230285377, Example 44)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617425(US20230285377, Example 13)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617461(US20230285377, Example 45)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617439(US20230285377, Example 25)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617431(US20230285377, Example 19)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617434(US20230285377, Example 21)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617444(US20230285377, Example 30)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617449(US20230285377, Example 33)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617441(US20230285377, Example 27)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617443(US20230285377, Example 29)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617454(US20230285377, Example 38)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617456(US20230285377, Example 40)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617457(US20230285377, Example 41)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617421(US20230285377, Example 9)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617450(US20230285377, Example 34)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617414(US20230285377, Example 3)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617453(US20230285377, Example 37)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617462(US20230285377, Example 46)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617427(US20230285377, Example 15)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617463(US20230285377, Example 47)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617429(US20230285377, Example 17)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617458(US20230285377, Example 42)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617459(US20230285377, Example 43)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617436(US20230285377, Example 23)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617437(US20230285377, Example 24)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617430(US20230285377, Example 18)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617432(US20230285377, Example 20)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617440(US20230285377, Example 26)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617442(US20230285377, Example 28)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617435(US20230285377, Example 22)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617420(US20230285377, Example 8)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent