Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 11609
TargetCytochrome P450 2C9(Human)
Simcere Pharmaceutical

US Patent
LigandPNGBDBM633147(US20230348459, Example 7)
Affinity DataIC50: 8.00E+3nMAssay Description:I. Test Materials and Instruments1. Human liver microsomes (Corning 452117)2. NADPH (Solarbio 705Y021)3. Positive substrates diclofenac (Sigma SLBV34...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetCytochrome P450 2C9(Human)
Simcere Pharmaceutical

US Patent
LigandPNGBDBM633146(US20230348459, Example 4 | Synthesis of (S)-N-(3,5...)
Affinity DataIC50: 2.00E+4nMAssay Description:I. Test Materials and Instruments1. Human liver microsomes (Corning 452117)2. NADPH (Solarbio 705Y021)3. Positive substrates diclofenac (Sigma SLBV34...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Simcere Pharmaceutical

US Patent
LigandPNGBDBM633147(US20230348459, Example 7)
Affinity DataIC50: 2.30E+4nMAssay Description:I. Test Materials and Instruments1. Human liver microsomes (Corning 452117)2. NADPH (Solarbio 705Y021)3. Positive substrates diclofenac (Sigma SLBV34...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Simcere Pharmaceutical

US Patent
LigandPNGBDBM633146(US20230348459, Example 4 | Synthesis of (S)-N-(3,5...)
Affinity DataIC50: 2.70E+4nMAssay Description:I. Test Materials and Instruments1. Human liver microsomes (Corning 452117)2. NADPH (Solarbio 705Y021)3. Positive substrates diclofenac (Sigma SLBV34...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent

TargetCytochrome P450 2C9(Human)
Simcere Pharmaceutical

US Patent
LigandPNGBDBM633145(US20230348459, Example 3)
Affinity DataIC50: 3.00E+4nMAssay Description:I. Test Materials and Instruments1. Human liver microsomes (Corning 452117)2. NADPH (Solarbio 705Y021)3. Positive substrates diclofenac (Sigma SLBV34...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Simcere Pharmaceutical

US Patent
LigandPNGBDBM633145(US20230348459, Example 3)
Affinity DataIC50: 3.00E+4nMAssay Description:I. Test Materials and Instruments1. Human liver microsomes (Corning 452117)2. NADPH (Solarbio 705Y021)3. Positive substrates diclofenac (Sigma SLBV34...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent