Compile Data Set for Download or QSAR
Report error Found 317 Enz. Inhib. hit(s) with all data for entry = 11819
TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650658((2R,3S)-1-(benzylsulfonyl)-2-(4- (cyclopentylamino...)
Affinity DataIC50: 2.55E+3nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650660(2-(4-(cyclopentylamino)phenyl)-1-(2-fluoro-6-methy...)
Affinity DataIC50: 2.55E+3nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650664((2R,3S,4aR,7aR)-2-(4-(cyclopentylamino)phenyl)-1-(...)
Affinity DataIC50: 2.55E+3nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650665((2R,3S,4aR,7aR)-2-(4-(cyclopentylamino)phenyl)-1-(...)
Affinity DataIC50: 2.55E+3nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650666((2R,3S,4aR,7aR)-2-(4-(cyclopentylamino)phenyl)-N-(...)
Affinity DataIC50: 2.55E+3nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650670(cis-2-(4-(cyclopentylamino)phenyl)-1-(2-fluoro-6- ...)
Affinity DataIC50: 2.55E+3nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650677(cis-2-(4-(cyclopentylamino)phenyl)-1-(2-fluoro-6- ...)
Affinity DataIC50: 2.55E+3nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650680(cis-2-(4-(cyclopentylamino)phenyl)-1-(2-fluoro-6- ...)
Affinity DataIC50: 2.55E+3nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650681(cis-N-(benzo[d]oxazol-6-yl)-2-(4- (cyclopentylamin...)
Affinity DataIC50: 2.55E+3nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650685(cis-2-(4-(cyclopentylamino)phenyl)-N-(2,3- dihydro...)
Affinity DataIC50: 2.55E+3nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650693((2R,3S,4aR,7aR)-2-(4-(cyclopentylamino)phenyl)-1-(...)
Affinity DataIC50: 2.55E+3nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650695((2R,3S,4aR,7aR)-1-(2-fluoro-6-methylbenzoyl)-N-(1-...)
Affinity DataIC50: 2.55E+3nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650698((2R,3S,4aR,7aR)-N-(4-(dimethylamino)phenyl)-1-(2- ...)
Affinity DataIC50: 2.55E+3nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650700((2R,3S,4aR,7aR)-1-(2-fluoro-6-methylbenzoyl)-N-(1H...)
Affinity DataIC50: 2.55E+3nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650702((2R,3S,4aR,7aR)-1-(2-fluoro-6-methylbenzoyl)-N-(1-...)
Affinity DataIC50: 2.55E+3nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650713(cis-2-(4-(cyclopentylamino)phenyl)-N-(4-methyl-3- ...)
Affinity DataIC50: 2.55E+3nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650715(cis-2-(4-(cyclopentylamino)phenyl)-1-(2-fluoro-6- ...)
Affinity DataIC50: 2.55E+3nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650716((2R,3S,4aR,7aS)-2-(4-(cyclopentylamino)phenyl)-1-(...)
Affinity DataIC50: 2.55E+3nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650721((2R,3S,4aR,7aS)-2-(4-(cyclopentylamino)phenyl)-1-(...)
Affinity DataIC50: 2.55E+3nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650721((2R,3S,4aR,7aS)-2-(4-(cyclopentylamino)phenyl)-1-(...)
Affinity DataIC50: 2.55E+3nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650727((2R,3S,4aR,7aS)-2-(4-(cyclopentylamino)phenyl)-1-(...)
Affinity DataIC50: 2.55E+3nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650731(cis-2-(4-(cyclopentylamino)phenyl)-1-(2-fluoro-6- ...)
Affinity DataIC50: 2.55E+3nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650733(cis-1-(2-fluoro-6-methylbenzoyl)-N-(1-methyl-1H- i...)
Affinity DataIC50: 2.55E+3nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650741((2R,3S)-2-(4-(cyclopentylamino)phenyl)-N-(4-methyl...)
Affinity DataIC50: 2.55E+3nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650741((2R,3S)-2-(4-(cyclopentylamino)phenyl)-N-(4-methyl...)
Affinity DataIC50: 2.55E+3nMAssay Description:Migration assay was performed by using polycarbonate membrane with 3.0 m pore (Corning). U937/C5aR cells were collected and washed twice by PBS; cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650661((3S,4R)-4-(4-(cyclopentylamino)phenyl)-N-(4-methyl...)
Affinity DataIC50: 2.55E+3nMAssay Description:Migration assay was performed by using polycarbonate membrane with 3.0 m pore (Corning). U937/C5aR cells were collected and washed twice by PBS; cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650663((2R,3S,4aR,7aR)-2-(4-(cyclopentylamino)phenyl)-1-(...)
Affinity DataIC50: 2.55E+3nMAssay Description:Migration assay was performed by using polycarbonate membrane with 3.0 m pore (Corning). U937/C5aR cells were collected and washed twice by PBS; cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650715(cis-2-(4-(cyclopentylamino)phenyl)-1-(2-fluoro-6- ...)
Affinity DataIC50: 2.55E+3nMAssay Description:Migration assay was performed by using polycarbonate membrane with 3.0 m pore (Corning). U937/C5aR cells were collected and washed twice by PBS; cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650716((2R,3S,4aR,7aS)-2-(4-(cyclopentylamino)phenyl)-1-(...)
Affinity DataIC50: 2.55E+3nMAssay Description:Migration assay was performed by using polycarbonate membrane with 3.0 m pore (Corning). U937/C5aR cells were collected and washed twice by PBS; cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650664((2R,3S,4aR,7aR)-2-(4-(cyclopentylamino)phenyl)-1-(...)
Affinity DataIC50: 2.55E+3nMAssay Description:Migration assay was performed by using polycarbonate membrane with 3.0 m pore (Corning). U937/C5aR cells were collected and washed twice by PBS; cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650680(cis-2-(4-(cyclopentylamino)phenyl)-1-(2-fluoro-6- ...)
Affinity DataIC50: 2.55E+3nMAssay Description:Migration assay was performed by using polycarbonate membrane with 3.0 m pore (Corning). U937/C5aR cells were collected and washed twice by PBS; cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650665((2R,3S,4aR,7aR)-2-(4-(cyclopentylamino)phenyl)-1-(...)
Affinity DataIC50: 2.55E+3nMAssay Description:Migration assay was performed by using polycarbonate membrane with 3.0 m pore (Corning). U937/C5aR cells were collected and washed twice by PBS; cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650694(cis-1-(2-fluoro-6-methylbenzoyl)-N-(4-methyl-3- (t...)
Affinity DataIC50: 2.55E+3nMAssay Description:Migration assay was performed by using polycarbonate membrane with 3.0 m pore (Corning). U937/C5aR cells were collected and washed twice by PBS; cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650721((2R,3S,4aR,7aS)-2-(4-(cyclopentylamino)phenyl)-1-(...)
Affinity DataIC50: 2.55E+3nMAssay Description:Migration assay was performed by using polycarbonate membrane with 3.0 m pore (Corning). U937/C5aR cells were collected and washed twice by PBS; cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650733(cis-1-(2-fluoro-6-methylbenzoyl)-N-(1-methyl-1H- i...)
Affinity DataIC50: 2.55E+3nMAssay Description:Migration assay was performed by using polycarbonate membrane with 3.0 m pore (Corning). U937/C5aR cells were collected and washed twice by PBS; cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650695((2R,3S,4aR,7aR)-1-(2-fluoro-6-methylbenzoyl)-N-(1-...)
Affinity DataIC50: 2.55E+3nMAssay Description:Migration assay was performed by using polycarbonate membrane with 3.0 m pore (Corning). U937/C5aR cells were collected and washed twice by PBS; cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650666((2R,3S,4aR,7aR)-2-(4-(cyclopentylamino)phenyl)-N-(...)
Affinity DataIC50: 2.55E+3nMAssay Description:Migration assay was performed by using polycarbonate membrane with 3.0 m pore (Corning). U937/C5aR cells were collected and washed twice by PBS; cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650702((2R,3S,4aR,7aR)-1-(2-fluoro-6-methylbenzoyl)-N-(1-...)
Affinity DataIC50: 2.55E+3nMAssay Description:Migration assay was performed by using polycarbonate membrane with 3.0 m pore (Corning). U937/C5aR cells were collected and washed twice by PBS; cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650754(cis-1-(2-fluoro-6-methylbenzoyl)-N-(1-methyl-1H- i...)
Affinity DataIC50: 2.55E+3nMAssay Description:Migration assay was performed by using polycarbonate membrane with 3.0 m pore (Corning). U937/C5aR cells were collected and washed twice by PBS; cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650738(((2R,3S)-3-(6-(tert-butyl)-1H-benzo[d]imidazol-2-y...)
Affinity DataIC50: 2.55E+3nMAssay Description:Migration assay was performed by using polycarbonate membrane with 3.0 m pore (Corning). U937/C5aR cells were collected and washed twice by PBS; cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650732(cis-2-(4-(cyclopentylamino)phenyl)-1-(2-fluoro-6-m...)
Affinity DataIC50: 2.55E+3nMAssay Description:U937/C5aR cells or HEK293/C5aR cells were washed by PBS and suspended in growth media at the density of 1 106 cells/ml. Seed 2 cell suspension to the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650663((2R,3S,4aR,7aR)-2-(4-(cyclopentylamino)phenyl)-1-(...)
Affinity DataIC50: 2.55E+3nMAssay Description:U937/C5aR cells or HEK293/C5aR cells were washed by PBS and suspended in growth media at the density of 1 106 cells/ml. Seed 2 cell suspension to the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650694(cis-1-(2-fluoro-6-methylbenzoyl)-N-(4-methyl-3- (t...)
Affinity DataIC50: 2.55E+3nMAssay Description:U937/C5aR cells or HEK293/C5aR cells were washed by PBS and suspended in growth media at the density of 1 106 cells/ml. Seed 2 cell suspension to the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650744((2R,3S)-2-(4-(cyclopentylamino)phenyl)-N-(4-methyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650745(cis-2-(4-(cyclopentyl(methyl)amino)phenyl)-1-(2-fl...)
Affinity DataIC50: 1.00E+4nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650746(tert-butyl 6-cis-2-(4-(cyclopentylamino)phenyl)-1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650748((2R,3S)-2-(4-(cyclopentylamino)phenyl)-N-(4-methyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Migration assay was performed by using polycarbonate membrane with 3.0 m pore (Corning). U937/C5aR cells were collected and washed twice by PBS; cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650749((2R,3S)-2-(4-(cyclopentyl(1,7-naphthyridin-8- yl)a...)
Affinity DataIC50: 1.00E+4nMAssay Description:Migration assay was performed by using polycarbonate membrane with 3.0 m pore (Corning). U937/C5aR cells were collected and washed twice by PBS; cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650751(cis-4-(4-(cyclopentylamino)phenyl)-N-(4-methyl-3- ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Migration assay was performed by using polycarbonate membrane with 3.0 m pore (Corning). U937/C5aR cells were collected and washed twice by PBS; cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650689(cis-2-(4-(cyclopentylamino)phenyl)-1-(2-fluoro-6- ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Migration assay was performed by using polycarbonate membrane with 3.0 m pore (Corning). U937/C5aR cells were collected and washed twice by PBS; cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

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